100 Longitudinal follow-up of endothelial function in pregnant women with chronic hypertension and normal blood pressure

2016 ◽  
Vol 6 (3) ◽  
pp. 227
Author(s):  
Mário Dias Corrêa ◽  
Augusto Fulgêncio Brandão ◽  
Guilherme Castro Rezende ◽  
Alim Alves Demian ◽  
Henrique Vitor Leite ◽  
...  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Eun Sun Yu ◽  
Kwan Hong ◽  
Byung Chul Chun

Abstract Background The study aimed to estimate the incidence of and period of progression to stage 2 hypertension from normal blood pressure. Methods We selected a total of 21,172 normotensive individuals between 2003 and 2004 from the National Health Insurance Service-Health Screening and followed them up until 2015. The criteria for blood pressure were based on the American College of Cardiology/American Heart Association 2017 guideline (normal BP: SBP < 120 and DBP < 80 mmHg, elevated BP: SBP 120–129 and DBP < 80 mmHg, stage 1 hypertension: SBP 130–139 or DBP 80–89 mmHg, stage 2 hypertension: SBP ≥140 or DBP ≥ 90 mmHg). We classified the participants into four courses (Course A: normal BP → elevated BP → stage 1 hypertension→ stage 2 hypertension, Course B: normal BP → elevated BP → stage 2 hypertension, Course C: normal BP → stage 1 hypertension → stage 2 hypertension, Course D: normal BP → stage 2 hypertension) according to their progression from normal blood pressure to stage 2 hypertension. Results During the median 12.23 years of follow-up period, 52.8% (n= 11,168) and 23.6% (n=5004) of the participants had stage 1 and stage 2 hypertension, respectively. In particular, over 60 years old had a 2.8-fold higher incidence of stage 2 hypertension than 40–49 years old. After the follow-up period, 77.5% (n=3879) of participants with stage 2 hypertension were found to be course C (n= 2378) and D (n=1501). After the follow-up period, 77.5% (n=3879) of participants with stage 2 hypertension were found to be course C (n= 2378) and D (n=1501). The mean years of progression from normal blood pressure to stage 2 hypertension were 8.7±2.6 years (course A), 6.1±2.9 years (course B), 7.5±2.8 years (course C) and 3.2±2.0 years, respectively. Conclusions This study found that the incidence of hypertension is associated with the progression at each stage. We suggest that the strategies necessary to prevent progression to stage 2 hypertension need to be set differently for each target course.


1986 ◽  
Vol 70 (2) ◽  
pp. 155-157 ◽  
Author(s):  
Karen Stainer ◽  
Rachel Morrison ◽  
C. Pickles ◽  
A. J. Cowley

1. Forearm venous tone was measured in two groups of pregnant women: one group with pregnancy-induced hypertension and the other group with normal blood pressure. 2. The women with pregnancy-induced hypertension were venoconstricted in the forearm (P < 0.01) compared with the pregnant women with normal blood pressure. However, there was no difference in venous tone between the women with pregnancy-induced hypertension and nonpregnant women. 3. There was an inverse correlation between mean arterial blood pressure and forearm venous tone (r = −0.581, P < 0.001) for all the pregnant women studied. Further evaluation of peripheral venous tone may provide valuable information about the pathophysiology and treatment of women with pregnancy-induced hypertension.


2017 ◽  
Vol 8 (3) ◽  
pp. 328-332
Author(s):  
Safura Hatamipour Dehno ◽  
Simin Taghavi ◽  
Nayyereh Ayati

Objectives: Hypertension, as a common problem during pregnancy, is a major cause of maternal and fetal morbidity and mortality. Anti-hypertensive drugs are used to prolong the pregnancy or modify perinatal outcomes in pregnant women with hypertensive disorders. Severe monitoring of blood pressure is subsequently essential in these mothers. The aim of this study was to evaluate the correlation between divided doses of chronic hypertensive drugs and the end of pregnancy in mothers with gestational hypertension. Materials and Methods: In this prospective research, 99 pregnant women with chronic hypertension, who were treated with antihypertensive medicines, were studied during pregnancy. During routine follow-up of these mothers, the number of the drug and the divided doses were recorded. The incidence of maternal and fetal outcomes were evaluated according to the number of less or more than 5 divided doses. Results: Maternal and fetal-baby complications were observed in 5.50 and 5.53% cases, respectively. The incidence of maternal and fetal complications were significantly enhanced by increasing the number of up-taken anti-hypertensive drugs. The maternal and fetal-baby complications were higher in mothers who received more than five divided doses compared to those who received less than five doses. Conclusion: Based on our results, chronic hypertension was associated with maternal and fetal-baby complications in half of the cases. It is clarified that precise blood pressure monitoring and regularly taking of anti-hypertensive medicine may decrease the hypertension side effects. The awareness about this field in the pre-pregnancy consulting is considered as the patients’ rights and should be respected.


2021 ◽  
Vol 39 (Supplement 1) ◽  
pp. e210
Author(s):  
Naomi Miyamatsu ◽  
Shin Murata ◽  
Tomoko Okamoto ◽  
Mizuki Ichikawa ◽  
Saori Azuma ◽  
...  

2021 ◽  
Vol 7 (1) ◽  
pp. 46-50
Author(s):  
Rizka Nur Fadilah ◽  
Dessy Hermawan ◽  
Yulistiana Evayanti ◽  
Devi Kurniasari

ABSTRACT RELATIONSHIP PATTERN BEYOND ITS ACTIVITY ROOM WITH A BLOOD PRESSURE IN PREGNANT WOMEN  Background        :Indonesia is a tropical area with sun exposure occurs throughout the year, but the Indonesian population is still at risk for vitamin D.This happens because one of them is female using a closed clothes are still many activities carried out in an enclosed space that does not get direct sunlight exposure , Another thing that affects vitamin D deficiency that women who use clothes covered and rarely exposed to sunlight, as well as women who always use sunscreen also contribute to prevent the entry of ultraviolet rays from the sun to the skin, so that reduced synthesis of vitamin D in the skin as well as a lack of vitamin D . as a result, the risk of degenerative diseases such as hypertension.Purpose from research to determine the relationship between outdoor activity patterns and blood pressure in pregnant women at PMB Fitri Hayati, SST Bandar Lampung in 2019.Method :The study design using analytic correlation using primary data. Conducted from June to August with the sample in the study were as many as 30 respondents. Research by the sampling technique is random sampling. Collecting data using questionnaires and statistical data analysis using chi square test.result     : From the results of research conducted by the authors that note of 6 respondents were active in the building as much as 4 respondents (66.7%) blood pressure is not normal and 2 respondents (33.3%) normal blood pressure. While 24 respondents were active outside the building as much as 3 respondents (12.5%) abnormal blood pressure and 21 respondents (87.5%) normal blood pressure. The results of chi-square statistic test obtained with p-value = 0.005<α (0.05). With the obtained value is a systolic blood pressure of 100-130 and diastolic 70-80 mmHg.Conclusion   : There is a pattern of activity outdoors relationship with blood pressure in pregnant women in PMB FitriHayati, SST Bandar Lampung 2019.Suggestion It is hoped that this research can be applied by the respondents to be one of the solutions in order to stabilize blood pressure or prevent hypertension or anemia. This can be done at least every 3 times a week from 07.00 - 09.00 for a minimum time between 15-30 minutes. This can be done for those who are wearing hijab, if they leave the house wearing long clothes, it is recommended that when inside the house they are wearing short clothes, exposure to the sun can be from the window glass or behind the house that is beaged but there can still be light entering the house and avoid wearing sunblock in the morning. can block the content on exposure to direct sunlight.  Keywords     : The pattern of activity outdoors, Blood Pressure, Vitamin D   ABSTRAK Latar Belakang  :Indonesia merupakan daerah tropis dengan paparan sinar matahari terjadi sepanjang tahun, tetapi penduduk Indonesia masih berisiko mengalami kekurangan vitamin D. Hal ini terjadi karena salah satunya yaitu perempuan menggunakan pakaian tertutup yang masih banyak kegiatan yang dilakukan di dalam ruang tertutup yang tidak mendapatkan paparan sinar matahari langsung. Hal lain yang mempengaruhi kekurangan vitamin D yaitu perempuan yang menggunakan pakaian tertutup dan jarang terpapar sinar matahari, serta perempuan yang selalu menggunakan tabir surya juga berperan menghambat masuknya sinar ultraviolet dari sinar matahari ke kulit, sehingga berkurang sintesa vitamin D di kulit serta kurangnya konsumsi vitamin D. Akibatnya berisiko terjadinya penyakit degeneratif seperti hipertensi.Tujuan dari penelitian Untuk mengetahui hubungan pola aktifitas diluar ruangan dengan Tekanan Darah pada ibu hamil di PMB Fitri Hayati, SST Bandar Lampung Tahun 2019.Metode :Desain penelitian menggunakan analitik dengan pendekatan korelasi menggunakan data primer. Dilakukan dari bulan Juni sampai dengan Agustus dengan sampel dalam penelitian adalah sebanyak 30 orang responden. Penelitian dengan teknik sampling yaitu random sampling. Pengumpulan data menggunakan kuisioner dan analisa data menggunakan uji statistic chi square.Hasil      :Dari hasil penelitian yang dilakukan oleh penulis bahwa diketahuidari 6 responden yang aktifdidalamgedungsebanyak 4 responden (66,7%) Tekanandarahtidak normal dan 2 responden (33,3%) Tekanandarah normal.Sedangkandari 24 responden yang aktifdiluargedungsebanyak 3 responden (12,5%) tekanandarahtidak normal dan 21 responden (87,5%) Tekanandarah normal.Hasiluji statistic chi-squarediperolehdengannilaip-value = 0,005<α (0,05). Dengandidapatnilaitekanandarahyaitusistolik 100 – 130 dan diastolic 70 – 80 mmHg.Kesimpulan  : Ada hubunganpolaaktifitasdiluarruangandengantekanandarahpadaibuhamil di PMB FitriHayati, SST Bandar Lampung Tahun 2019.Saran Diharapkan dengan adanya penelitian ini dapat diaplikasikan oleh para responden untuk dijadikan salah satu solusi agar dapat menstabilkan tekanan darah ataupun mencegah terjadinya hipertensi maupun anemia. Ini bisa dilakukan minimal setiap seminggu 3 kali dari pukul 07.00 – 09.00 dalam waktu minimal antara 15 – 30 menit. Ini bisa dilakukan bagi yang berhijab jika keluar rumah memakai pakaian panjang disarankan ketika didalam rumah sedang memakai pakaian pendek melakukan paparan sinar matahari bisa dari kaca jendela ataupun belakang rumah yang dipager namun masih bisa ada cahaya yang masuk kedalam rumah dan hindari memakai sunblock pada pagi hari yang dapat menghalangi kandungan pada paparan sinar matahari langsung. Kata Kunci    :PolaAktifitasdiluarruangan, TekananDarah, Vitamin D  


2020 ◽  
Vol 48 (8) ◽  
pp. 030006052094787
Author(s):  
Xueling Wu ◽  
Gang Yang ◽  
Shiyu Chen ◽  
Min Tang ◽  
Shan Jian ◽  
...  

Bartter syndrome is a rare inherited disease caused by CLCNKB mutation, which results in inactivation of the chloride channel Kb protein. Bartter syndrome is characterized by extreme hypokalemia, hypochloremia, metabolic alkalosis, hyperrenin-induced angiotensinemia, hyperaldosteronemia, and normal blood pressure. We herein report a case of Bartter syndrome that manifested as vomiting, hypokalemia, metabolic alkalosis, normal blood pressure, and significant hyperrenin-induced angiotensinemia. The patient, a 5-month-old girl, carried two known heterozygous pathogenic mutations: c.88C > T (p.Arg30*), which she had inherited from her father, and c.1313G > A (p.Arg438His), which she had inherited from her mother. Treatment with indomethacin, a nonsteroidal anti-inflammatory drug, led to rapid improvement of the hypokalemia, and treatment was continued for 14 years. The indomethacin also induced a sustainable reduction in the hypokalemia and metabolic alkalosis.


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