Oral long acting antipsychotic penfluridol as a harm reduction treatment in a patient suffering from untreated schizophrenia and multiple drug dependence: a case report.

2021 ◽  
pp. 114147
Author(s):  
Charles Dauré ◽  
Maeva Fortias ◽  
Romain Icick ◽  
Clément Delage ◽  
Vanessa Bloch ◽  
...  
MISSION ◽  
2020 ◽  
pp. 17-19
Author(s):  
Marianna Boso ◽  
Irene Famularo ◽  
Guido Nosari ◽  
Alessandro Castellana ◽  
Elena Costantino ◽  
...  
Keyword(s):  

Il moltiplicarsi dell'offerta di opportunità di gioco d'azzardo anche in luoghi a bassa soglia di accesso e non dedicati in maniera esclusiva (bar, centri commerciali, tabaccherie), ha rinnovato l'interesse degli esperti riguardo ai costi sociali, economici e psicologici associati a tale pratica.Il comportamento del gioco d'azzardo può condurre ad una dipendenza, riconosciuta e classificata dal DSM5 e può comportare la compromissione del paziente dal punto di vista psichico, familiare e sociale. Questa patologia colpisce una percentuale variabile dall'1% al 3% della popolazione generale. Pertanto, in Lombardia, il numero di persone affette da questo problema potrebbe variare fra 100.000 e 300.000.Nel presente case report viene discusso il caso di un giovane con scompenso psicotico di tipo schizoaffettivo e GAP, che si rivolge al SerD.


2009 ◽  
Vol 34 (4) ◽  
pp. 485-487 ◽  
Author(s):  
E. Montané ◽  
A. Barriocanal ◽  
I. Isern ◽  
T. Parajon ◽  
J. Costa

2014 ◽  
Vol Ano 4 ◽  
pp. 32-34
Author(s):  
VICTOR SICILIANO SOARES ◽  
CLAUDIANE SALLES DALTIO ◽  
CECÍLIA ATTUX

Este artigo relata o caso de um paciente jovem em primeiro episódio psicótico e com dificuldade de adesão ao tratamento, no qual foi utilizado um antipsicótico de segunda geração de ação prolongada. Os antipsicóticos de longa ação devem ser considerados mais amplamente no tratamento da esquizofrenia pela facilidade do manejo e segurança na tomada da medicação, pois melhoram a adesão e, consequentemente, o prognóstico dos pacientes.


2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Noa Krawczyk ◽  
Adetayo Fawole ◽  
Jenny Yang ◽  
Babak Tofighi

Abstract Background The COVID-19 pandemic has exerted a significant toll on the lives of people who use opioids (PWUOs). At the same time, more flexible regulations around provision of opioid use disorder (OUD) services have led to new opportunities for facilitating access to services for PWUOs. In the current scoping review, we describe new services and service modifications implemented by treatment and harm reduction programs serving PWUO, and discuss implications for policy and practice. Methods Literature searches were conducted within PubMed, LitCovid, Embase, and PsycInfo for English-language studies published in 2020 that describe a particular program, service, or intervention aimed at facilitating access to OUD treatment and/or harm reduction services during the COVID-19 pandemic. Abstracts were independently screened by two reviewers. Relevant studies were reviewed in full and those that met inclusion criteria underwent final data extraction and synthesis (n = 25). We used a narrative synthesis approach to identify major themes around key service modifications and innovations implemented across programs serving PWUO. Results Reviewed OUD treatment and harm reduction services spanned five continents and a range of settings from substance use treatment to street outreach programs. Innovative service modifications to adapt to COVID-19 circumstances primarily involved expanded use of telehealth services (e.g., telemedicine visits for buprenorphine, virtual individual or group therapy sessions, provision of donated or publicly available phones), increased take-home medication allowances for methadone and buprenorphine, expanded uptake of long-acting opioid medications (e.g. extended-release buprenorphine and naltrexone), home delivery of services (e.g. MOUD, naloxone and urine drug screening), outreach and makeshift services for delivering MOUD and naloxone, and provision of a safe supply of opioids. Conclusions The COVID-19 pandemic has posed multiple challenges for PWUOs, while simultaneously accelerating innovations in policies, care models, and technologies to lower thresholds for life-saving treatment and harm reduction services. Such innovations highlight novel patient-centered and feasible approaches to mitigating OUD related harms. Further studies are needed to assess the long-term impact of these approaches and inform policies that improve access to care for PWUOs.


2003 ◽  
Vol 15 (1) ◽  
pp. 85-88 ◽  
Author(s):  
R. Sari ◽  
H. Altunbas ◽  
M. Ozdogan ◽  
E.I. Gurer ◽  
U. Karayalcin

2020 ◽  
Vol 17 (1) ◽  
Author(s):  
M. Maticic ◽  
Z. Pirnat ◽  
A. Leicht ◽  
R. Zimmermann ◽  
T. Windelinck ◽  
...  

Abstract Background People who inject drugs (PWID) account for the majority of new cases of hepatitis C virus (HCV) infection in Europe; however, HCV testing, and treatment for PWID remain suboptimal. With the advent of direct acting antivirals (DAAs) the World Health Organization (WHO) adopted a strategy to eliminate HCV as public health threat by 2030. To achieve this, key policies for PWID must be implemented and HCV continuum of care needs to be monitored. This study presents results of the first monitoring led by civil society that provide harm reduction services for PWID. Methods In 2019, harm reduction civil society organizations representing focal points of Correlation-European Harm Reduction Network in 36 European countries were invited to complete a 27-item online survey on four strategic fields: use/impact of guidelines on HCV testing and treatment for PWID, availability/functioning of continuum of care, changes compared to the previous year and, the role of harm reduction services and non-governmental organizations (NGOs) of PWID. A descriptive analysis of the responses was undertaken. Results The response rate was 97.2%. Six countries reported having no guidelines on HCV treatment (17.1%). Twenty-three (65.7%) reported having treatment guidelines with specific measures for PWID; guidelines that impact on accessibility to HCV testing/treatment and improve access to harm reduction services in 95.6% and 86.3% of them, respectively. DAAs were available in 97.1% of countries; in 26.4% of them they were contraindicated for active drug users. HCV screening/confirmatory tests performed at harm reduction services/community centers, prisons and drug dependence clinics were reported from 80.0%/25.7%, 60.0%/48.6%, and 62.9%/34.3% of countries, respectively. Provision of DAAs at drug dependence clinics and prisons was reported from 34.3 to 42.9% of countries, respectively. Compared to the previous year, HCV awareness campaigns, testing and treatment on service providers’ own locations were reported to increase in 42.9%, 51.4% and 42.9% of countries, respectively. NGOs of PWID conducted awareness campaigns on HCV interventions in 68.9% of countries, and 25.7% of countries had no such support. Conclusion Further improvements in continuum-of-care interventions for PWID are needed, which could be achieved by including harm reduction and PWID organizations in strategic planning of testing and treatment and in efforts to monitor progress toward WHO 2030 elimination goal.


2020 ◽  
Vol 46 (Supplement_1) ◽  
pp. S117-S117
Author(s):  
Eva Sole ◽  
Juan Ignacio Duran ◽  
Sara Lera ◽  
Anna Torres ◽  
Susana Andres ◽  
...  

Abstract Background Long-acting injectable (LAI) antipsychotics provide some advantages in treatment compliance of psychotic disorders. However, information about their effects during pregnancy is still very limited. We expose a clinical case of aripiprazole LAI use in a pregnant woman diagnosed of schizophrenia. Methods A non-systematic review using Pubmed was conducted using the following terms: schizophrenia, pregnancy, aripiprazole and aripiprazole LAI. A clinical record review was performed for the clinical case report. Results We report the case of a 30-year-old woman diagnosed of schizophrenia. She required several hospital admissions in the past because of the mental disorder and the lack of treatment adherence, what was the consequence of having no insight of illness and her pregnancy desires. She was initially treated with risperidone, suffering from some adverse effects like prolactine elevation and amenorrhea. In the last hospital admission, she started treatment with aripiprazol 20mg, having a good tolerability and being finally changed into aripiprazole LAI 400mg/28days. No incidences were reported and stability was achieved. After five months, she became pregnant and started being followed up in the Perinatal Mental Health Unit that belongs to the same hospital. The severity of the mental disorder and her stability at that moment made psychiatrists; obstetricians and patient decide to keep the antipsychotic treatment with subsequent appointments. The goal was to supervise psychopathology and blood tests during pregnancy. Prolactine was in physiologic levels and there were no obstetric complications. She finally delivered at 41 gestational weeks to a 3465g baby girl (Apgar 1’: 9 Apgar 5’: 10). No neonatal complications were reported. The Stafford interview was also administered in order to explore her social, obstetric and psychological background as well as possible psychiatric complications due to pregnancy and puerperium. No psychiatric complications were reported. Postpartum Bounding Questionnaire was also administered. No bounding disorder was detected. Discussion Pregnancy and postpartum are periods that carry a high risk of illness onset or recurrence in women with severe mental disorders, such as schizophrenia. Having a good control of the symptoms may prevent from risks to both patient and child, due to the important influence that exists on the development of the baby and the mother-infant relationship.


2003 ◽  
Vol 50 (5) ◽  
pp. 507-513 ◽  
Author(s):  
Vedia TONYUKUK ◽  
Rifat EMRAL ◽  
Sule TEMIZKAN ◽  
Ayse SERTÇELIK ◽  
Ilhan ERDEN ◽  
...  

2020 ◽  
Vol 13 (10) ◽  
pp. e237238
Author(s):  
Bhavika Kakadia ◽  
Giselle Alexandra Suero-Abreu ◽  
Rrita Daci ◽  
Ryna Karina Then

Antiphospholipid syndrome (APLS) is an autoimmune condition that predisposes to venous and arterial thrombosis. Warfarin is the agent of choice for anticoagulation. However, a need for routine international normalised ratio (INR) checks and multiple drug interactions are some of the difficulties with warfarin. Currently, there is mixed evidence for and against the use of novel oral anticoagulants (NOACs) for thromboprophylaxis. We present a case report of a patient with APLS on a NOAC for secondary thromboprophylaxis who developed a stroke and discuss current evidence regarding the use of NOACs in patients with APLS. The patient was switched to warfarin for secondary thromboprophylaxis with an INR goal of 2–3. Literature review revealed mixed case reports for and against NOACs for secondary prevention of thrombotic events in patients with APLS. There needs to be further randomised controlled trials to evaluate the efficacy of NOACs for thromboprophylaxis in patients with APLS.


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