Increase in reported adverse events following seasonal influenza vaccination among the French armed forces, 2008–2009: Possible role of stimulated reporting and background cases of influenza-like infection

Public Health ◽  
2012 ◽  
Vol 126 (1) ◽  
pp. 70-76 ◽  
Author(s):  
A. Mayet ◽  
P. Nivoix ◽  
R. Haus-Cheymol ◽  
F. De Laval ◽  
C. Verret ◽  
...  
BMJ Open ◽  
2020 ◽  
Vol 10 (2) ◽  
pp. e031851 ◽  
Author(s):  
Peter Jacoby ◽  
Catherine Glover ◽  
Chloe Damon ◽  
Parveen Fathima ◽  
Alexis Pillsbury ◽  
...  

ObjectivesTo determine how soon after commencement of the seasonal influenza vaccination programme, the AusVaxSafety active vaccine safety surveillance system, currently in use across Australia, would have detected a safety signal had it been operating in 2010 when there was an unprecedented number of febrile seizures in young children associated with one specific influenza vaccine brand, Fluvax (CSL Biotherapies).DesignSimulation study.SettingWestern Australian vaccine influenza coverage and adverse event surveillance data.Outcome measuresSimulated solicited responses from caregivers who would have received an SMS survey about adverse events experienced following seasonal influenza vaccination of their children aged 6 months to <5 years.ParticipantsNone.ResultsWe estimated a >90% probability of a safety signal being detected by AusVaxSafety based on solicited reports for either fever or medical attendance at or before the week ending 28 March 2010, 3 weeks after the start of vaccine distribution. Suspension of the national paediatric influenza vaccination programme as a result of the passive adverse events surveillance operating at the time did not occur until 23 April 2010.ConclusionsActive vaccine safety surveillance leading to rapid detection of a safety signal would likely have resulted in earlier suspension of Fluvax from the vaccination programme, prevention of many febrile convulsions and maintenance of public confidence in influenza vaccination for young children.


PLoS ONE ◽  
2018 ◽  
Vol 13 (8) ◽  
pp. e0200934 ◽  
Author(s):  
Clara Mazagatos ◽  
Concepción Delgado-Sanz ◽  
Jesús Oliva ◽  
Alin Gherasim ◽  
Amparo Larrauri ◽  
...  

2010 ◽  
Vol 49 (3) ◽  
pp. 225-226
Author(s):  
Li-Juan Liu ◽  
Xiao-Ai Zhang ◽  
Mao-Ti Wei ◽  
Cui He ◽  
Lei Zhang ◽  
...  

Vaccine ◽  
2016 ◽  
Vol 34 (34) ◽  
pp. 3961-3966 ◽  
Author(s):  
Jeanet Kemmeren ◽  
Maaike Honsbeek ◽  
Frederika Dijkstra ◽  
Marit de Lange ◽  
Nicoline van der Maas ◽  
...  

Author(s):  
Amal M. Alshahrani ◽  
Hamzh Esam Mellebary ◽  
Yara Rashed A. Albayyahi ◽  
Ali Ibrahim Ali Alsakiti ◽  
Abdullaziz A. Alshahrani ◽  
...  

Background: Considering the important role of health workers in increasing seasonal influenza vaccination coverage and the similarity of seasonal influenza to COVID -19, it is important to increase vaccination rates to reduce the risk of both diseases. Objective: In this study, we aim to investigate how health workers perceive the importance of influenza vaccination, especially in the era of COVID -19. Results: The study involved 316 health workers from Abha in 2021, most of them were physicians, male and young. Participants agreed that influenza can be a serious illness and that the vaccine is very safe. Most HCWs would have preferred to inform their patients about the vaccine. This result changes if the patient disagrees with the COVID -19 vaccine. Conclusion: Despite the low rate of seasonal influenza vaccination, there is a need to recruit health workers to increase this rate, especially in the Covid 19 era.


2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Ausenda Machado ◽  
Irina Kislaya ◽  
Amparo Larrauri ◽  
Carlos Matias Dias ◽  
Baltazar Nunes

Abstract Background All aged individuals with a chronic condition and those with 65 and more years are at increased risk of severe influenza post-infection complications. There is limited research on cases averted by the yearly vaccination programs in high-risk individuals. The objective was to estimate the impact of trivalent seasonal influenza vaccination on averted hospitalizations and death among the high-risk population in Portugal. Methods The impact of trivalent seasonal influenza vaccination was estimated using vaccine coverage, vaccine effectiveness and the number of influenza-related hospitalizations and deaths. The number of averted events (NAE), prevented fraction (PF) and number needed to vaccinate (NVN) were estimated for seasons 2014/15 to 2016/17. Results The vaccination strategy averted on average approximately 1833 hospitalizations and 383 deaths per season. Highest NAE was observed in the ≥65 years population (85% of hospitalizations and 95% deaths) and in the 2016/17 season (1957 hospitalizations and 439 deaths). On average, seasonal vaccination prevented 21% of hospitalizations in the population aged 65 and more, and 18.5% in the population with chronic conditions. The vaccination also prevented 29% and 19.5% of deaths in each group of the high-risk population. It would be needed to vaccinate 3360 high-risk individuals, to prevent one hospitalization and 60,471 high-risk individuals to prevent one death. Conclusion The yearly influenza vaccination campaigns had a sustained positive benefit for the high-risk population, reducing hospitalizations and deaths. These results can support public health plans toward increased vaccine coverage in high-risk groups.


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