Cerebral effects of three resuscitation protocols in uncontrolled haemorrhagic shock: A randomised controlled experimental study

Resuscitation ◽  
2009 ◽  
Vol 80 (5) ◽  
pp. 567-572 ◽  
Author(s):  
Erol Cavus ◽  
Patrick Meybohm ◽  
Volker Doerges ◽  
Hans-Hermann Hugo ◽  
Markus Steinfath ◽  
...  
2019 ◽  
Vol 393 (1) ◽  
pp. 89-97
Author(s):  
Zoi Aidoni ◽  
Chryssa Pourzitaki ◽  
Eleni Stamoula ◽  
Katerina Kotzampassi ◽  
Georgia Tsaousi ◽  
...  

2021 ◽  
pp. bmjqs-2020-012740
Author(s):  
Eric Dryver ◽  
Jakob Lundager Forberg ◽  
Caroline Hård af Segerstad ◽  
William D Dupont ◽  
Anders Bergenfelz ◽  
...  

BackgroundStudies carried out in simulated environments suggest that checklists improve the management of surgical and intensive care crises. Whether checklists improve the management of medical crises simulated in actual emergency departments (EDs) is unknown.MethodsEight crises (anaphylactic shock, life-threatening asthma exacerbation, haemorrhagic shock from upper gastrointestinal bleeding, septic shock, calcium channel blocker poisoning, tricyclic antidepressant poisoning, status epilepticus, increased intracranial pressure) were simulated twice (once with and once without checklist access) in each of four EDs—of which two belong to an academic centre—and managed by resuscitation teams during their clinical shifts. A checklist for each crisis listing emergency interventions was derived from current authoritative sources. Checklists were displayed on a screen visible to all team members. Crisis and checklist access were allocated according to permuted block randomisation. No team member managed the same crisis more than once. The primary outcome measure was the percentage of indicated emergency interventions performed.ResultsA total of 138 participants composing 41 resuscitation teams performed 76 simulations (38 with and 38 without checklist access) including 631 interventions. Median percentage of interventions performed was 38.8% (95% CI 35% to 46%) without checklist access and 85.7% (95% CI 80% to 88%) with checklist access (p=7.5×10−8). The benefit of checklist access was similar in the four EDs and independent of senior physician and senior nurse experience, type of crisis and use of usual cognitive aids. On a Likert scale of 1–6, most participants agreed (gave a score of 5 or 6) with the statement ‘I would use the checklist if I got a similar case in reality’.ConclusionIn this multi-institution study, checklists markedly improved local resuscitation teams’ management of medical crises simulated in situ, and most personnel reported that they would use the checklists if they had a similar case in reality.


2016 ◽  
Vol 209 (1) ◽  
pp. 62-67 ◽  
Author(s):  
Daniel Freeman ◽  
Jonathan Bradley ◽  
Angus Antley ◽  
Emilie Bourke ◽  
Natalie DeWeever ◽  
...  

BackgroundPersecutory delusions may be unfounded threat beliefs maintained by safety-seeking behaviours that prevent disconfirmatory evidence being successfully processed. Use of virtual reality could facilitate new learning.AimsTo test the hypothesis that enabling patients to test the threat predictions of persecutory delusions in virtual reality social environments with the dropping of safety-seeking behaviours (virtual reality cognitive therapy) would lead to greater delusion reduction than exposure alone (virtual reality exposure).MethodConviction in delusions and distress in a real-world situation were assessed in 30 patients with persecutory delusions. Patients were then randomised to virtual reality cognitive therapy or virtual reality exposure, both with 30 min in graded virtual reality social environments. Delusion conviction and real-world distress were then reassessed.ResultsIn comparison with exposure, virtual reality cognitive therapy led to large reductions in delusional conviction (reduction 22.0%, P = 0.024, Cohen's d = 1.3) and real-world distress (reduction 19.6%, P = 0.020, Cohen's d = 0.8).ConclusionCognitive therapy using virtual reality could prove highly effective in treating delusions.


2002 ◽  
Vol 3 (1) ◽  
Author(s):  
Karen Grimmer ◽  
Brenton Dansie ◽  
Steve Milanese ◽  
Ubon Pirunsan ◽  
Patricia Trott

PLoS ONE ◽  
2011 ◽  
Vol 6 (10) ◽  
pp. e25929 ◽  
Author(s):  
Alison K. Gosby ◽  
Arthur D. Conigrave ◽  
Namson S. Lau ◽  
Miguel A. Iglesias ◽  
Rosemary M. Hall ◽  
...  

2018 ◽  
Vol 8 (1) ◽  
Author(s):  
Nicolas Libert ◽  
Guillaume Chenegros ◽  
Anatole Harrois ◽  
Nathalie Baudry ◽  
Gilles Cordurie ◽  
...  

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