scholarly journals Testing Protein Leverage in Lean Humans: A Randomised Controlled Experimental Study

PLoS ONE ◽  
2011 ◽  
Vol 6 (10) ◽  
pp. e25929 ◽  
Author(s):  
Alison K. Gosby ◽  
Arthur D. Conigrave ◽  
Namson S. Lau ◽  
Miguel A. Iglesias ◽  
Rosemary M. Hall ◽  
...  
Keyword(s):  
Experimental Study ◽  
Randomised Controlled

Circulatory effects of dexmedetomidine in early sepsis: a randomised controlled experimental study

2019 ◽  
Vol 393 (1) ◽  
pp. 89-97
Author(s):  
Zoi Aidoni ◽  
Chryssa Pourzitaki ◽  
Eleni Stamoula ◽  
Katerina Kotzampassi ◽  
Georgia Tsaousi ◽  
...  
Keyword(s):  
Experimental Study ◽  
Circulatory Effects ◽  
Early Sepsis ◽  
Randomised Controlled

scholarly journals Virtual reality in the treatment of persecutory delusions: Randomised controlled experimental study testing how to reduce delusional conviction

2016 ◽  
Vol 209 (1) ◽  
pp. 62-67 ◽  
Author(s):  
Daniel Freeman ◽  
Jonathan Bradley ◽  
Angus Antley ◽  
Emilie Bourke ◽  
Natalie DeWeever ◽  
...  
Keyword(s):  
Experimental Study ◽  
Virtual Reality ◽  
Cognitive Therapy ◽  
Real World ◽  
Social Environments ◽  
Persecutory Delusions ◽  
New Learning ◽  
Randomised Controlled ◽  
Virtual Reality Exposure ◽  
Real World Situation

BackgroundPersecutory delusions may be unfounded threat beliefs maintained by safety-seeking behaviours that prevent disconfirmatory evidence being successfully processed. Use of virtual reality could facilitate new learning.AimsTo test the hypothesis that enabling patients to test the threat predictions of persecutory delusions in virtual reality social environments with the dropping of safety-seeking behaviours (virtual reality cognitive therapy) would lead to greater delusion reduction than exposure alone (virtual reality exposure).MethodConviction in delusions and distress in a real-world situation were assessed in 30 patients with persecutory delusions. Patients were then randomised to virtual reality cognitive therapy or virtual reality exposure, both with 30 min in graded virtual reality social environments. Delusion conviction and real-world distress were then reassessed.ResultsIn comparison with exposure, virtual reality cognitive therapy led to large reductions in delusional conviction (reduction 22.0%, P = 0.024, Cohen's d = 1.3) and real-world distress (reduction 19.6%, P = 0.020, Cohen's d = 0.8).ConclusionCognitive therapy using virtual reality could prove highly effective in treating delusions.

Cerebral effects of three resuscitation protocols in uncontrolled haemorrhagic shock: A randomised controlled experimental study

Resuscitation ◽  
2009 ◽  
Vol 80 (5) ◽  
pp. 567-572 ◽  
Author(s):  
Erol Cavus ◽  
Patrick Meybohm ◽  
Volker Doerges ◽  
Hans-Hermann Hugo ◽  
Markus Steinfath ◽  
...  
Keyword(s):  
Experimental Study ◽  
Haemorrhagic Shock ◽  
Randomised Controlled

scholarly journals Adolescent standing postural response to backpack loads: a randomised controlled experimental study

2002 ◽  
Vol 3 (1) ◽  
Author(s):  
Karen Grimmer ◽  
Brenton Dansie ◽  
Steve Milanese ◽  
Ubon Pirunsan ◽  
Patricia Trott
Keyword(s):  
Experimental Study ◽  
Postural Response ◽  
Randomised Controlled

scholarly journals A Randomised Controlled Experimental Study on the Influence of Patient Age on Medical Decisions in Respect to the Diagnosis and Treatment of Depression in the Elderly

2009 ◽  
Vol 2009 ◽  
pp. 1-4 ◽  
Author(s):  
Michael Linden ◽  
Guido Kurtz
Keyword(s):  
Experimental Study ◽  
The Elderly ◽  
Diagnosis And Treatment ◽  
Medical Decision ◽  
Medical Illness ◽  
Patient Age ◽  
Patient Âgé ◽  
Therapeutic Decisions ◽  
Randomised Controlled ◽  
Illness Concepts

Background. Elderly patients are often treated differently than younger patients, even when suffering from the same disorder.Objective. The study examines the influence of “patient age” on the perception of symptoms and conclusions of physicians in respect to diagnosis and treatment.Methods. In a randomised controlled experimental study on medical decision-making, 121 general practitioners were given two case vignettes which contained all the criteria for major depression according to ICD-10, but differed in respect to the age of the patient (39 or 81). Reaction time, diagnostic conclusions and therapeutic recommendations were assessed by computer.Results. Depression and anxiety were significantly seen as more probable in the young cases and dementia and physical illness in the old. In young age, psychotherapy, pharmacotherapy and referral to a specialist or inpatient treatment were significantly more recommended than in old age, for whom supportive counselling was significantly more recommended. The time needed for a decision was significantly longer in the older patients.Conclusion. Ageing stereotypes can also form medical illness concepts and have a significant influence on diagnostic and therapeutic decisions.

scholarly journals COMPARISON OF PROKINETIC ACTIVITY OF RANITIDINE AND NEOSTIGMINE ALONE AND IN COMBINATION- AN IN VITRO STUDY

2021 ◽  
Vol 71 (Suppl-1) ◽  
pp. S66-70
Author(s):  
Aroosa Ishtiaq Butt ◽  
Asma Khan ◽  
Wardha Mazhar ◽  
Qamar uz Zaman Khan ◽  
Imrana Maqsood
Keyword(s):  
Experimental Study ◽  
Response Curve ◽  
Controlled Trial ◽  
In Vitro Study ◽  
Fixed Dose ◽  
Medical College ◽  
The Third ◽  
Percent Response ◽  
Randomised Controlled

Objective: To explore the prokinetic effect of Ranitidine, to compare it with the prokinetic effect of Neostigmineand to observe the potentiating prokinetic effect of Ranitidine and Neostigmine in combination. Study Design: Randomised controlled trial (experimental study). Place and Duration of Study: Multi disciplinary centre, Army Medical College, Rawalpindi, from Jan to Dec 2015. Methodology: Experiments were performed on three groups of rabbits (n=6) and Cumulative dose responsecurves were plotted using isolated duodenal tissue on power lab (USA). In the first two groups of experiments,cumulative concentrations of Neostigmine and Ranitidine were studied separately with neostigmine acting as acontrol and in the third group the potentiating effect of a fixed dose of ranitidine on neostigmine was evaluated. Results: Neostigmine’s response was taken as 100 percent and Ranitidine’s response when compared to it came out to be 197 percent. The dose response curve of Neostigmine was shifted to the left and upwards in the presence of Ranitidine. The percent response with Neostigmine alone was taken as 100 percent and increased to 212 percent when the tissue was pre-treated with Ranitidine. Conclusion: Our study has indicated that Ranitidine has marked prokinetic effect which is found to be greaterthan Neostigmine. It is also inferred that Ranitidine can potentiate the prokinetic effect of Neostigmine.

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