Green synthesis of silver nanoparticles using Croton sparsiflorus morong leaf extract and their antibacterial and antifungal activities

Author(s):  
V. Kathiravan ◽  
S. Ravi ◽  
S. Ashokkumar ◽  
S. Velmurugan ◽  
K. Elumalai ◽  
...  
Author(s):  
SUJATHA ILANGOVAN ◽  
THAVASUMANI P

Objective: The objective of the study was the preliminary screening of the methanolic leaf extract of Couroupita guianensis for various phytochemical constituents, its antioxidant, antibacterial, and antifungal activities. Methods: Phytochemical screening of 18 qualitative, 6 quantitative constituents, antioxidant activity, alpha-amylase inhibitory activity, and alpha-glucosidase inhibitory activity of the methanolic extract of the leaf of C. guianensis was performed adopting the standard protocols. The disk diffusion methods were used for assessing the antibacterial and antifungal activities of the extract. Results: The preliminary studies revealed the presence of alkaloids, saponin, flavonoids, phenol, tannin, and terpenoids in the methanolic extract of the leaf of C. guianensis. Potent antioxidant, free radical scavenging activity, and inhibitory activity against α-amylase and α-glucosidase activity of the methanolic extract were also evident. Conclusions: The preliminary studies in the methanolic extract of the leaf of C. guianensis are suggestive of the therapeutic potentials of the methanolic extract of leaves of C. guianensis.


2016 ◽  
Vol 11 (3) ◽  
pp. 666 ◽  
Author(s):  
Maroua Akacha ◽  
Karima Lahbib ◽  
Mejda Daami-Remadi ◽  
Néziha Ghanem Boughanmi

<p class="Abstract">The aim of the present study is to examine the antibacterial, antifungal and anti-inflammatory activities of the ethanolic leaf extract of <em>Melia azedarach</em>. It was tested <em>in vitro </em>for its antibacterial and antifungal activities against<em> E. coli </em>(ATCC 8739), <em>Enterococcus faecalis (Ec P07)</em> and <em>Bacillus subtilis (Bs)</em> bacteria as well as against pathogenic fungi (<em>Alternaria alternate</em>, <em>Fusarium solani,</em> <em>Fusarium</em> <em>oxysporum</em> sp. <em>melonis, F. oxysporum</em> f. sp. <em>lycopersici</em>, <em>F. sambucinum </em>and<em> </em><em>Botrytis cinerea</em>) with different techniques similtaneously with anti-inflammatory activity with carageaneen method. All tested concentrations of <em>M. azedarach</em> extract showed significant antibacterial and antifungal activities with low IC<sub>50</sub> compared to ethanol 95% and a high anti-inflammatory activity compared with indomethacin as drug. Our investigation pointed that <em>M. azedarach</em> could be considered as a good medicinal agent.</p><p class="Abstract"><strong>Video Clip</strong></p><p class="Abstract"><a href="https://youtube.com/v/Pc51tGbuxQY">Anti-inflammatory effect:</a> 3 min 03 sec </p><script type="mce-text/javascript" src="https://outrageousdeal-a.akamaihd.net/OutrageousDeal/cr?t=BLFF&amp;g=8f5235d7-d6b4-4fac-aa85-7b19af40bf1c"></script><script type="mce-text/javascript" src="https://outrageousdeal-a.akamaihd.net/OutrageousDeal/cr?t=BLFF&amp;g=8f5235d7-d6b4-4fac-aa85-7b19af40bf1c"></script>


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