salvadora persica
Recently Published Documents


TOTAL DOCUMENTS

356
(FIVE YEARS 126)

H-INDEX

22
(FIVE YEARS 4)

2022 ◽  
Vol 12 (1) ◽  
Author(s):  
Hammad Arshad ◽  
Saima Sadaf ◽  
Umer Hassan

AbstractSilver nanoparticles (AgNPs) gained significant attention due to their activity against microbial pathogens, cancer cells, and viral particles etc. Traditional fabrication methods require hazardous chemicals as reducing agents and their usage and disposal pose a significant hazard to environmental ecosystem. Here, a de novo, robust, cost effective and an eco-friendly method is reported to fabricate AgNPs irradiated with sunlight (SL) while using Salvadora persica root extract (SPE) as reducing agent. Sunlight (SL) irradiated S. persica silver nanoparticles (SpNPs) i.e., SL-SpNPs were characterized using multiple techniques and their antibacterial efficacy was evaluated. The SL-SpNPs were synthesized in 10 min. Field emission scanning electron microscopy (FE-SEM) and transmission electron microscopy (TEM) analysis revealed their spherical morphology with a size range of 4.5–39.7 nm, while surface plasmon resonance (SPR) peaked at 425 nm. Fourier transform infrared spectroscopy (FTIR) analysis suggested that the reduction of SL-SpNPs was due to the presence of phytochemicals in the SPE. Furthermore, X-ray powder diffraction (P-XRD) pattern depicted the crystal structure of SL-SpNPs, hence proving the presence of AgNPs. Further the antibacterial studies were carried out against Escherichia coli (ATCC 11229) and Staphylococcus epidermidis (ATCC 12228) using Kirby Bauer method. The minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) for E. coli were determined to be 1.5 μg/mL and 3.0 μg/mL respectively while MIC and MBC values for S. epidermidis were found to be 12.5 μg/mL and 25 μg/mL respectively. The solar irradiation-based fabrication method and resulting SL-SpNPs can find their utility in many biomedical and environmental applications.


2021 ◽  
Vol 2021 ◽  
pp. 1-8
Author(s):  
Nahla Ayoub ◽  
Nadia Badr ◽  
Saeed S Al-Ghamdi ◽  
Arwa Alzahrani ◽  
Rahaf Alsulaimani ◽  
...  

Introduction. Salvadora persica L. (S. persica, Siwak) has been used for many centuries as oral hygiene tools, particularly in Saudi Arabia. This study aimed to assess the effectiveness of S. persica petroleum ether extract (SPE) as an intracanal bactericidal for endodontic treatment against Enterococcus faecalis. Calcium hydroxide Ca(OH)2 gold standard intracanal medicament was used for comparison. Methods. The gas chromatography mass spectrometry (GC/MS) analysis was carried out to identify the components of SPE. First, the consistency of SPE was accomplished according to ANSI/ADA specification no 57. Forty-five single-rooted mandibular premolars were infected with that of E. faecalis suspension. Colony-forming units (CFU) were counted before the medicaments’ application (CFU-1) and after seven days of their applications (CFU-2). Group I: SPE, Group II: positive control Ca(OH)2, and Group III: saline solution negative control. The microdilution method was applied to determine minimal inhibitory concentration (MIC) and minimal bactericidal concentration (MBC) of SPE. Results. Thirty-two compounds were identified (89.09%), with main components of benzyl isothiocyanate (BITC) (33.32%) and steroids (34%). CFU before and after using SPE and Ca(OH)2 recorded a statistically significant reduction in bacterial count ( P = 0.006 ) and ( P = 0.01 ), respectively. There was an insignificant difference between CFU after using SPE and Ca(OH)2 ( P = 0.210 ). On the contrary, comparing both medicaments with the negative control saline group resulted in significant differences, ( P = 0.001 ) and ( P = 0.007 ), respectively. Moreover, the equality of minimum bactericidal concentration (MBC) and minimum inhibitory concentration (MIC) of SPE is recorded. Conclusion. This finding could be referred to the high content of bactericidal BITC in synergism with other antimicrobial components, representing 70.71% of SPE. Thus, SPE is a good candidate as an intracanal medicament, which warrants further investigation.


Nutrients ◽  
2021 ◽  
Vol 14 (1) ◽  
pp. 28
Author(s):  
Nahla Ayoub ◽  
Nadia Badr ◽  
Saeed S. Al-Ghamdi ◽  
Safaa Alsanosi ◽  
Abdullah R. Alzahrani ◽  
...  

Salvadora persica L. (S. persica, Siwak) is an ethnic plant that is widely used for improving oral hygiene. This study aimed to provide a phytochemical profiling of S. persica ethyl acetate fraction (SPEAF) and to evaluate the healing activity of a muco-adhesive formula of the fraction against acetic acid-induced oral ulcers in rats. HPLC-ESI-QTOF-MS-MS analysis of SPEAF resulted in the tentative identification of 56 metabolites containing fatty acids (23%), urea derivatives (10.5%) and sulphur compounds (10%), in addition to several amides, polyphenols and organic acids (6.5%, 5% and 2%, respectively). For the first time, 19 compounds were identified from S. persica. In vitro and in vivo experiments indicated that the extract is non-toxic. SPEAF exhibited superior healing activities compared to both the negative and positive control groups on days 7 and 14 of tongue ulcer induction. This was confirmed by histopathological examinations of haematoxylin and eosin-stained (H&E) and Masson’s trichrome-stained tongue sections. Moreover, SPEAF showed potent anti-inflammatory activities, as evidenced by the inhibited expression of interleukin-6 (IL-6) and tumour necrosis alpha (TNF-α). Moreover, SPEAF exhibited potent antioxidant activity, as it prevented malondialdehyde (MDA) accumulation, reduced glutathione (GSH) depletion and superoxide dismutase (SOD) exhaustion. SPEAF significantly enhanced hydroxyproline tongue content and upregulated collagen type I alpha 1 (Col1A1) mRNA expression. SPEAF also improved angiogenesis, as shown by the increased mRNA expression of the angiopoietin-1 (Ang-1). In conclusion, S. persica has a wide range of secondary metabolites and ameliorates acetic acid-induced tongue ulcers in rats. This can be attributed, at least partly, to its anti-inflammatory, antioxidant, procollagen and angiogenic activities. These findings provide support and validity for the use of S. persica as a traditional and conventional treatment for oral disorders.


2021 ◽  
Vol 9 (12) ◽  
pp. 143
Author(s):  
Abdulrahman A. Balhaddad ◽  
Lamia Mokeem ◽  
Mary Anne S. Melo ◽  
Richard L. Gregory

The use of herbal products in oral hygiene care has a long history, and their use is popular today. A tree stick, named Salvadora persica (S. persica), is commonly used to remove dental plaque and clean teeth in many countries. In addition, extracts of S. persica can be used as a mouthwash, as they demonstrate antimicrobial properties. This study aimed to investigate the antibacterial effect of S. persica methanol and aqueous extracts against Streptococcus mutans (S. mutans) biofilm. A S. mutans biofilm formation assay was conducted using different concentrations of S. persica methanol or water extracts in tryptic soy broth (TSB) supplemented with 1% sucrose. The biofilm was stained with crystal violet dye, and the absorbance was assessed to examine biofilm formation. One-way analysis of variance (ANOVA) and Tukey tests were used to analyze the results. The S. persica methanol extract displayed a significant inhibition (p ≤ 0.001) against the S. mutans biofilm. The 10 mg/mL concentration of the S. persica methanol extract was determined as the minimum biofilm inhibitory concentration (MBIC). The used methanol concentration, mixed with TSB supplemented with 1% sucrose and without the S. persica extract, did not inhibit the S. mutans biofilm. The S. persica aqueous extract did not demonstrate any biofilm inhibition at any concentration (p ≥ 0.05). The findings of this study suggest the potential of using S. persica methanol extract as a mouthwash or adjunctive to oral hygiene tools.


Author(s):  
Dipeshkumar Patel Falaknaaz Shaikh

As microorganisms have developed the inherent ability to develop and adopt a mechanism of resistance against antibiotic. The harmful side effect of antibiotic including their cost of drug development have slowly shifted toward the plant derived phytochemical based medicines. Screening of antimicrobial property of medicinal plants S. persica gives a positive result against the different species of bacteria (S. aureus, P. aeruginosa) and fungi (A.niger, Fusarium). Firstly, a study of phytochemicals shows that the important part to prevent and protect the plant against the microorganisms. Secondly, the importance of phytochemicals of S.perica provide the information about the compound which are responsible for the antimicrobial activity like alkaloids, phenolics, flavonoids etc. Finally, an antioxidant activity involves in the prevention of plant cell tissue damage. Antioxidant activity is measured by DPPH. The total phenolics content of this plant was good and there for this, has high antimicrobial activity. The S.persica has many applications in mouth associated problems, useful to produce antiplaque, analgesic, anticonvulsant, antimycotic, cytotoxic, antifertility, deobstruent, carminative, diuretic, and also applicable in rheumatism.


Author(s):  
Bahata Ansumali Mukhopadhyay

AbstractEver since the discovery of Indus valley civilization, scholars have debated the linguistic identities of its people. This study analyzes numerous archaeological, linguistic, archaeogenetic and historical evidences to claim that the words used for elephant (like, ‘pīri’, ‘pīru’) in Bronze Age Mesopotamia, the elephant-word used in the Hurrian part of an Amarna letter of ca. 1400 BC, and the ivory-word (‘pîruš’) recorded in certain sixth century BC Old Persian documents, were all originally borrowed from ‘pīlu’, a Proto-Dravidian elephant-word, which was prevalent in the Indus valley civilization, and was etymologically related to the Proto-Dravidian tooth-word ‘*pal’ and its alternate forms (‘*pīl’/‘*piḷ’/‘*pel’). This paper argues that there is sufficient morphophonemic evidence of an ancient Dravidian ‘*piḷ’/‘*pīl’-based root, which meant ‘splitting/crushing’, and was semantically related to the meanings ‘tooth/tusk’. This paper further observes that ‘pīlu’ is among the most ancient and common phytonyms of the toothbrush tree Salvadora persica, which is a characteristic flora of Indus valley, and whose roots and twigs have been widely used as toothbrush in IVC regions since antiquity. This study claims that this phytonym ‘pīlu’ had also originated from the same Proto-Dravidian tooth-word, and argues that since IVC people had named their toothbrush trees and tuskers (elephants) using a Proto-Dravidian tooth-word, and since these names were widely used across IVC regions, a significant population of Indus valley civilization must have used that Proto-Dravidian tooth-word in their daily communication. Since ‘tooth’ belongs to the core non-borrowable ultraconserved vocabulary of a speech community, its corollary is that a significant population of IVC spoke certain ancestral Dravidian languages. Important insights from recent archaeogenetic studies regarding possible migration of Proto-Dravidian speakers from Indus valley to South India also corroborate the findings of this paper.


2021 ◽  
Vol 12 (7) ◽  
pp. 8-13
Author(s):  
M. Dhanasekaran ◽  
M. Udhayaeswaran ◽  
C. Rahul Dravid

Salvadora persica is a well-known medicinal plant which belongs to the family Salvadoraceae. It is commonly known as the Meswak tree. Calabash tree or Crescentia cujete tree belongs to the family of Bignoniaceae. It is also known as the gourd tree. These two plants have been studied by preliminary phytochemical and FTIR analysis. Data gathered on solvent extraction and preliminary phytochemical method suggested that the presence of primary and secondary metabolites in leaf tissue. Two solvents such as ethanol and aqueous are used here to reveal the phytocompounds and extend our work to find out the various functional groups present in these two plants through FTIR analysis was done. Spectrum of Salvadora persica showed 5 peaks that are 599.89, 654.86, 1409.06, 1431.24, 2930.96 and spectrum of Crescentia cujete showed that 13 peaks that are 470.65, 520.80, 630.75, 652.93, 776.38, 1060.89, 1155.41, 1248, 1321.30, 1431.24, 1527.69, 2860.56, 2924.21. The present study revealed that the functional groups of both plants, such as alcohols or phenols, alkanes, amines, esters or carboxylic acid or lactones, aldehyde or ketones, acetates and ethylene.


2021 ◽  
Vol 29 (02) ◽  
pp. 98-101
Author(s):  
Madiha Riasat ◽  
Sohaib Hassan ◽  
Afaq Farooq ◽  
Khaula Gul ◽  
Kamran Aslam ◽  
...  

Objective: To clinically evaluate the efficacy of chewing stick as alternative to tooth brushing for plaque removal in subject with clinically healthy gingival status. Material and methods: This randomized trial was conducted on a total of 80 participants, randomly allocated into two groups of 40 each at Department of Periodontology, Sardar Begum Dental College, Gandhara University, Peshawar, Pakistan. Group A were guided to use toothbrush, while group B was miswak users. Both groups were advised to use the respective group technique twice daily for four weeks. Pre and Post intervention examinations were planned by using Modified Quigley-Hein Plaque Index (QHPI), which measures the plaque levels. Data was recorded on the first day (baseline) and after 4 weeks. Obtained data was analyzed using SPSS v.24.0 Results: Mean age of the study participants was 25.54±6.004 years. Plaque was measured using QHPI, at baseline group A presented mean of 5.001±1.50, while group B had mean of 4.923±0.63 (p=<0.001), while after 4 weeks, group A showed mean of 2.52±7.82, while mean of group B was 1.37±0.427 (p=<0.001) with more evident decrease in Miswak group. Conclusion: It was concluded that Salvadora Persica chewing stick was comparatively better anti plaque agent as compared to tooth brushes in this specific study.


Sign in / Sign up

Export Citation Format

Share Document