P11. The role of the LRP5 gene in vertebral body strength

2005 ◽  
Vol 5 (4) ◽  
pp. S114-S115
Author(s):  
Kimihiko Sawakami ◽  
Alexander G. Robling ◽  
Minrong Ai ◽  
Matthew L. Warman ◽  
Charles H. Turner
Keyword(s):  
Vertebral Body ◽  
Body Strength

The Role of Vertebral Body Tethering in Treating Skeletally Immature Scoliosis

2021 ◽  
pp. 155633162110088
Author(s):  
Blake C. Meza ◽  
Andre M. Samuel ◽  
Todd J. Albert
Keyword(s):  
Vertebral Body ◽  
Revision Surgery ◽  
Critical Analysis ◽  
Posterior Spinal Fusion ◽  
Future Research ◽  
Skeletally Immature ◽  
Postoperative Results ◽  
Radiographic Outcomes ◽  
Novel Technology

This is a critical analysis of a study by Hoernschemeyer et al, “Anterior Vertebral Body Tethering for Adolescent Scoliosis with Growth Remaining: A Retrospective Review of 2 to 5-Year Postoperative Results” ( J Bone Joint Surg Am, 2020;102[13]:1169–1176), that assessed the clinical and radiographic outcomes of vertebral body tethering (VBT) in the treatment of adolescent scoliosis. The authors demonstrated successful treatment in 74% of patients, based on radiographic outcomes and avoidance of subsequent posterior spinal fusion. Nearly a quarter of patients required revision surgery. Almost half suffered a broken tether, although the effects of such complications are not fully understood. The study provided valuable information for determining which patients are reasonable candidates for VBT and emphasizes several questions surrounding this novel technology that remain unanswered. This analysis discusses the study’s strengths and weaknesses, suggests potential directions of future research, and examines the potential indications for VBT.

scholarly journals Improvements in Vertebral Body Strength Under Teriparatide Treatment Assessed In Vivo by Finite Element Analysis: Results From the EUROFORS Study

2009 ◽  
Vol 24 (10) ◽  
pp. 1672-1680 ◽  
Author(s):  
Christian Graeff ◽  
Yan Chevalier ◽  
Mathieu Charlebois ◽  
Peter Varga ◽  
Dieter Pahr ◽  
...  
Keyword(s):  
Finite Element Analysis ◽  
Finite Element ◽  
Vertebral Body ◽  
Element Analysis ◽  
Teriparatide Treatment ◽  
Body Strength

Effect of the Pedicle and Posterior Arch on Vertebral Body Strength Predictions in Finite Element Modeling

Spine ◽  
1998 ◽  
Vol 23 (8) ◽  
pp. 899-907 ◽  
Author(s):  
Cari M. Whyne ◽  
Serena S. Hu ◽  
Stephen Klisch ◽  
Jeffrey C. Lotz
Keyword(s):  
Finite Element ◽  
Finite Element Modeling ◽  
Vertebral Body ◽  
Posterior Arch ◽  
Element Modeling ◽  
Body Strength

Effect of loading rate on endplate and vertebral body strength in human lumbar vertebrae

2003 ◽  
Vol 36 (12) ◽  
pp. 1875-1881 ◽  
Author(s):  
Ruth S Ochia ◽  
Allan F Tencer ◽  
Randal P Ching
Keyword(s):  
Vertebral Body ◽  
Loading Rate ◽  
Lumbar Vertebrae ◽  
Body Strength

Surgical Decompression of Anterior and Posterior Malignant Epidural Tumors Compressing the Spinal Cord: A Prospective Study

Neurosurgery ◽  
1985 ◽  
Vol 17 (3) ◽  
pp. 424-432 ◽  
Author(s):  
Tzony Siegal ◽  
Tali Siegal
Keyword(s):  
Vertebral Body ◽  
Bladder Dysfunction ◽  
Primary Treatment ◽  
Surgical Decompression ◽  
Vertebral Body Replacement ◽  
Surgical Morbidity ◽  
Postoperative Death ◽  
Bowel And Bladder Dysfunction ◽  
Indications For Operation

Abstract Of 167 episodes of spinal epidural neoplastic compression, 86 were treated by operation. The surgical approach was prospectively selected according to the location of the tumor in the spinal canal. Decompression was achieved by 61 vertebral body resections (VBRs) and by 25 laminectomies. The indications for operation were: (a) neurological relapse after previous radiotherapy, (b) the need to make a tissue diagnosis, (c) a radioresistant tumor, and (d) neurological deterioration during radiotherapy. Before VBR, 28% (17 of 61) were still able to walk, 51% (31 of 61) were pareparetic, and 21% (13 of 61) were paraplegic. Bowel and bladder dysfunction was present in 49% (30 of 61). After VBR, the outcome of only 57 procedures was available for evaluation because of the postoperative death of 4 patients. Eighty per cent (46 of 57) were able to walk, 18% (10 of 57) were paraparetic, and 2% (1 of 57) were paraplegic. Ninety-three per cent had normal sphincter control. Before laminectomy, 8% (2 of 25) were ambulatory, 84% (21 of 25) were paraparetic, and 8% (2 of 25) were paraplegic. Bowel and bladder dysfunction was present in 76% (19 of 25). After laminectomy, only 23 procedures were evaluated because of the postoperative death of 2 patients. Thirty-nine per cent (9 of 23) were ambulatory, 35% (8 of 23) were paraparetic, and 26% (6 of 23) were paraplegic. Fifty-seven per cent regained normal sphincter control. The operative mortality was 7% (4 of 61) in VBR and 8% (2 of 25) in laminectomy. The surgical morbidity was 11% (7 of 61) in VBR and 28% (7 of 25) in laminectomy, mainly delayed wound healing. Neurological worsening as a result of laminectomy occurred in 20% (5 of 25) and was transient after 1 VBR (2%). Dislodgement of the vertebral body replacement construct occurred in 3 patients, but has not occurred since the introduction of an improved instrumentation technique. In view of the encouraging results with anterior decompression of the spine, the role of surgical decompression as the primary treatment for ventrally located tumors should be reconsidered. The role of laminectomy in posterior compartment tumors deserves further study.

scholarly journals ROLE OF HEMANT RITU (EARLY WINTER) FOR MAINTEINANCE AND ENHANCEMENT OF BALA (STRENGTH)

2021 ◽  
Vol 9 (4) ◽  
pp. 829-832
Author(s):  
Shilpa Kachhawaha ◽  
Rajesh Kumar Sharma ◽  
Dinesh Chandra Sharma
Keyword(s):  
The Body ◽  
The Sun ◽  
Heating Effect ◽  
Human Beings ◽  
The Moon ◽  
Review Of Literature ◽  
The Earth ◽  
Body Strength ◽  
The World

Seasons (Ritus) are the inherent global earth clock and the rhythm of the world. As per Ayurveda year is divided into six seasons, in which three season Shishira, Vasanta and Greeshma are known as Aadanakala . Other three seasons Varsha, Sharad and Hemanta are said to be Visargakala. In Visarga kala, as the Sun is located in southwards position, its heat reduces or slows down due to the effect of time and its position with respect to the Earth, wind, cloud and rain. The power of the Moon is predominant. Rainwater decreases the heating effect of nature. All of these lead to the predominance of non- dryunctuous, amla (sour), lavana (salty), and madhura (sweet) rasa respectively and step by step rise of body strength in human beings during these three seasons. Out of all the Ritus, Hemanta Ritu is a unique Ritu in terms of having uttam bala. Falling in Dakshinayana, moon is very powerful than sun, Madhur rasa is predominant in this Ritu, so the strength (Bala) of person enhances during this period. This article focuses to disclose thorough review of literature of Hemant ritucharya and its implication towards maintenance and enhancement of Uttam Bala. In Ayurveda oja, veerya, prana, kapha etc terms are considered as synonyms of Bala. Besides prakruti(genetic), sara(physiological) and aahar(diet), kala (season) is one of the prime factors to govern the Bala of the person. Bala stands for the strength of the body in terms of physical, mental, immunological and resistance to the body, the word Bala is being used in different contexts to denote various aspects accordingly. Keywords: Visarga kala, Hemant ritu, Bala

Role of Vertebral Shell and Endplate Modulus on Whole Vertebral Body Stiffness

1999 ◽  
Author(s):  
Michael A. K. Liebschner ◽  
David L. Kopperdahl ◽  
Tony M. Keaveny
Keyword(s):  
Computed Tomography ◽  
Cortical Bone ◽  
Vertebral Body ◽  
Fracture Strength ◽  
Shell Thickness ◽  
Bone Geometry ◽  
Image Resolution ◽  
Cortical Shell ◽  
Cortical Bone Geometry

Abstract The contribution of the cortical shell and endplate to the stiffness and strength of the vertebral body is not well understood. However, several studies have suggested that the cortical shell plays an important role in the fracture strength of the whole vertebral body as bone is progressively lost from the centrum due to aging and osteoporosis (Eastell 1991, Faulkner 1991, Kurowski 1986. Silva 1997). Silva et al. (1994) concluded that prediction of cortical bone geometry using computed tomography (CT) based measurements is subject to considerable uncertainly caused by image distortion and the low ratio of image resolution of 0.25 mm/pixel to cortical shell thickness (0.09–0.86 mm). Thus, in development of CT-based models of the vertebral body, particular attention should be paid to the details of shell modeling.

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