scholarly journals Effects of flunixin meglumine, recombinant bovine somatotropin and/or human chorionic gonadotropin on pregnancy rates in Nelore cows

2011 ◽  
Vol 76 (4) ◽  
pp. 751-758 ◽  
Author(s):  
R.C. Rossetti ◽  
A. Perdigão ◽  
F.S. Mesquita ◽  
M. Sá Filho ◽  
G.P. Nogueira ◽  
...  
Keyword(s):  
Chorionic Gonadotropin ◽  
Human Chorionic Gonadotropin ◽  
Pregnancy Rates ◽  
Bovine Somatotropin ◽  
Recombinant Bovine Somatotropin ◽  
Flunixin Meglumine

scholarly journals Effect of progesterone, human chorionic gonadotropin and progesterone + human chorionic gonadotropin treatment on conception rates in repeat breeder cows

2020 ◽  
Vol 89 (4) ◽  
pp. 307-315
Author(s):  
Hasan Alkan ◽  
Huseyin Erdem
Keyword(s):  
Pregnancy Rate ◽  
Chorionic Gonadotropin ◽  
Human Chorionic Gonadotropin ◽  
Artificial Insemination ◽  
Fixed Time ◽  
Pregnancy Rates ◽  
Group 4 ◽  
Prostaglandin F ◽  
Repeat Breeder ◽  
Group 1

The aim of this study was to investigate the effects of hormonal support on the pregnancy rate in repeat breeder cows. Prostaglandin F2α + Ovsynch oestrus synchronization protocol was applied to the cows. Following the fixed time insemination (day 0), the cows were divided into 4 groups. In Group 1 (n = 42), progesterone releasing intravaginal device (PRID) was placed vaginally at 84 h and removed on the 9th day after the artificial insemination. In Group 2 (n = 40), the cows were administered human chorionic gonadotropin (hCG) on the 7th day. Group 3 (n = 45) was applied a combination of progesterone and hCG. Group 4 (n = 42) was not given any treatment. Blood samples were collected from all cows 4 times on days 3.5, 7, 12, and 18 to evaluate progesterone concentrations. The pregnancy rates were 40.47%, 37.50%, 44.44%, and 30.95% in Group 1, 2, 3, and 4, respectively (P > 0.05). In addition, in cows with progesterone concentrations <2 ng/ml on day 3.5, the pregnancy rates were found to be lower than in the cows with progesterone concentrations >2 ng/ml in Group 4 (P < 0.05). Progesterone supplementation in cows with progesterone concentrations < 2 ng/ml appeared to increase pregnancy rates (P < 0.05) in Groups 1 and 3. As a result, post-insemination hormonal applications in the repeat breeder cows did not increase the pregnancy rate. However, it was concluded that determination of progesterone concentrations on day 3.5 following artificial insemination and then hormonal support in the cows with low concentrations would increased the pregnancy rate.

scholarly journals Effects of human chorionic gonadotropin intrauterine injection on oocyte retrieval day on assisted reproductive techniques outcomes: An RCT

2021 ◽  
pp. 773-780
Author(s):  
Robabe Hosseinisadat ◽  
Lida Saeed ◽  
Sareh Ashourzadeh ◽  
Sedigheh Safar Heidari ◽  
Victoria Habibzadeh
Keyword(s):  
Chorionic Gonadotropin ◽  
Human Chorionic Gonadotropin ◽  
Oocyte Retrieval ◽  
Pregnancy Rates ◽  
Clinical Pregnancy ◽  
Assisted Reproductive Techniques ◽  
Control Group ◽  
Case Group ◽  
Reproductive Techniques ◽  
Clinical Pregnancy Rates

Background: Several mediators play an important role in implantation. One of these mediators is human chorionic gonadotropin (HCG). Objective: To evaluate the effects of HCG intrauterine injection on the day of oocyte retrieval on the result of assisted reproductive techniques (ART). Materials and Methods: In this randomized clinical trial study, 126 women who were referred to Afzalipour Infertility Center between December 2018 to December 2019 undergoing in vitro fertilization/intracytoplasmic sperm injection cycles were enrolled and assigned to two groups of: a case (n = 62) and a control group (n = 64). The protocols for both groups were the same; except that the case group was injected with the protocols for both groups were the same, except that the case group was injected with 1000 IU of HCG into uterine cavity following the oocyte puncture, while no medication was administered to the control group. The implantation rate, chemical pregnancy, clinical pregnancy, and abortion rates were compared between the two groups. Results: Positive chemical pregnancy was seen in 15 (27.3%) cases of the case group and 14 (25.5%) of the control group. No significant difference was seen in the chemical and clinical pregnancy rates between the groups. The abortion rate was higher in the control group but that was not significant. Conclusion: A 1000 IU of HCG intrauterine injection after oocyte retrieval does not improve implantation, chemical or clinical pregnancy rates in ART cycles. Further studies are needed to clearly understand the role of HCG intrauterine injection in the day of oocyte retrieval in ART outcomes. Key words: Oocyte retrieval, Chorionic gonadotropin, Pregnancy, Assisted reproductive techniques.

173 A COMBINED RECOMBINANT BOVINE SOMATOTROPIN/EQUINE CHORIONIC GONADOTROPIN PROTOCOL IN THE ZEBU BREED TABAPUA AND HOLSTEIN HEIFERS SUBMITTED TO OVUM PICKUP

2011 ◽  
Vol 23 (1) ◽  
pp. 188
Author(s):  
J. C. de Souza ◽  
H. de Morais ◽  
R. Spuri ◽  
R. C. Andrade ◽  
T. L. C. Pinto
Keyword(s):  
Chorionic Gonadotropin ◽  
Transvaginal Ultrasound ◽  
Ovarian Follicle ◽  
Interactive Effect ◽  
Bovine Somatotropin ◽  
Recombinant Bovine Somatotropin ◽  
Oocyte Yield ◽  
Equine Chorionic Gonadotropin ◽  
And Control ◽  
Zebu Breed

The aim of this study was to enhance ovarian follicular development and subsequent oocyte retrieval by the use of a combined equine chorionic gonadotropin (eCG) and recombinant bovine somatotropin (rbST) protocol, as well as to compare its efficiency between the Brazilian zebu breed Tabapua (TAB) and Holstein (HOL) nulliparous heifers. In a changeover design, TAB (n = 16) and HOL (n = 12) were allocated to 1 of 2 protocols in 2 distinct periods. Two days before initiation of the protocols (D2), dominant follicles were ablated by transvaginal ultrasound-guided aspiration: Group 1: on day 0 (D0) a subcutaneous injection of 500 mg of rbST (Boostin®, Intervet, SP) and on D2 an intramuscular injection of 500 IU of eCG (Novormon®, Schering-Plough-Intervet, SP); and control: vehicle only. Two days later (D4), ovum pickup (OPU) was performed and the ovarian follicle population was evaluated by ultrasound. Twenty days after the first OPU session, heifers were switched over across treatments and were aspirated a second time, so that a total of 28 sessions were performed for each treatment. Main effects of period, breed, and protocol and their interactions on follicle numbers and oocyte yield were analysed through the GENMOD procedure of SAS (SAS®, Cary, NC, USA) using the Poisson distribution option. Means were compared by orthogonal contrasts, and the probability value set at 0.05 for significance unless otherwise specified. There was an interaction effect between hormonal stimulation and breed (P < 0.05) on the number of aspirated follicles (2 to 10 mm in diameter) such that they were higher in TAB treated (41.4 ± 2.6) compared with control (29.9 ± 2.6) heifers and did not differ between the HOL heifers (15.5 ± 2.6 v. 14.4 ± 2.6 in treated and control heifers, respectively). Overall, follicle numbers were higher (P < 0.0001) in TAB (35.6 ± 1.84) than in HOL (15.0 ± 2.1) heifers and in treated (28.4 ± 2.0) v. control (22.1 ± 2.0) heifers (P < 0.001). There was no effect (P = 0.77) of treatment on total viable oocytes (grades 1 to 3) between treated (3.5 ± 1.2) and control (3.9 ± 1.1) heifers. Tabapuã heifers had more (P < 0.05) viable oocytes than HOL (5.9 ± 0.9 v. 1.6 ± 1.4). In conclusion, the proposed protocol may improve OPU results but viable oocyte yield was not associated to the higher number of follicles available for aspiration. It may be necessary to modify this protocol to improve results perhaps by increasing the time window between rbST and eCG injections as well as by increasing the rbST dosage for heifers. The present protocol may be cost saving, compared with follicle stimulating hormone, for initial OPU sessions in the case of Tabapuã heifers because it is expected that responses decrease after a sequence of eCG injections. It is also interesting to notice that it is possible that HOL heifers already have higher endogenous growth hormone concentrations, which could help to explain the interactive effect observed in the ovarian response. Further studies are necessary to improve this protocol especially in HOL heifers. CNPQ, CAPES, Schering-Plough-Intervet.

Human chorionic gonadotropin affects original (ovulatory) and induced (accessory) corpora lutea, progesterone concentrations, and pregnancy rates in anestrous dairy goats

2022 ◽  
Vol 22 (1) ◽  
pp. 100591
Author(s):  
Juliana Nascimento Duarte Rodrigues ◽  
José Domingos Guimarães ◽  
Maria Emilia Franco Oliveira ◽  
Jenniffer Hauschildt Dias ◽  
Aline Matos Arrais ◽  
...  
Keyword(s):  
Chorionic Gonadotropin ◽  
Human Chorionic Gonadotropin ◽  
Pregnancy Rates ◽  
Corpora Lutea ◽  
Dairy Goats

scholarly journals Effectiveness of Letrozole and Human Chorionic Gonadotropin Injection in Ovulation Induction: A Cohort Study

2021 ◽  
Author(s):  
Peter Chukwudi Udealor ◽  
Eric Ezenwa Asimadu ◽  
Emeka Iloghalu
Keyword(s):  
Cohort Study ◽  
Chorionic Gonadotropin ◽  
Human Chorionic Gonadotropin ◽  
Ovulation Induction ◽  
Intrauterine Insemination ◽  
Statistical Significance ◽  
Pregnancy Rates ◽  
Significant Difference ◽  
Ovulation Stimulation ◽  
Group A

Introduction: Ovulation stimulation followed by timed intercourse or Intrauterine Insemination (IUI) is widely used for treatment of anovulatory infertility. Aim: To compare the effectiveness of Letrozole (LE) alone versus LE and human chorionic gonadotropin injection in ovulation induction and pregnancy rates in women undergoing ovulation induction/follicular tracking in Enugu, Nigeria. Materials and Methods: The longitudinal cohort study was carried out in University of Nigeria Teaching Hospital and Livingston Specialist Gynaecological Hospital in Enugu, Nigeria. Study population were women coming for ovulation stimulation/follicular tracking. Ovulation was confirmed by ultrasound evidence of ovulation with a progesterone level of greater or equal to 25 nmol/L on day 21, positive pregnancy test/ultrasound detection of a gestational sac. Patients were consecutively assigned to group A or B. Group A received LE only for the induction while group B received 10000 IU of human chorionic gonadotropin injection in addition to LE. A total of 5 mg of LE was given daily from day 3 to day 7. The primary outcome measured was the number of ruptured/crenated follicles on either arm while the secondary outcomes were the number of Luteinised Unruptured Follicles (LUF) and pregnancy rates. The Statistical analysis was performed using the Statistical Package for the Social Sciences version 21.0 software (SPSS Inc., Chicago, IL, United States). Results: A total of 50 women were in each arm of the study. There was no significant difference in age and parity between the two arms. There was no significance difference between the period of infertility and the number of the previous cycles of ovulation stimulation. (p=0.444 and 0.526, respectively). Ovulation was significantly associated with HCG injection (p=0.001). However, there was no statistical significance between both arms regarding the number of LUF (p=0.216). HCG injection was significantly associated with pregnancy. Subjects who took HCG injection were over two times more likely to become pregnant than those without HCG injection (OR=2.488, 95% CI for OR=1.057-5.857, p=0.037). Conclusion: This study showed that both the ovulation rate and pregnancy rate are significantly improved when human chorionic gonadotrophin injection is given after ovarian stimulation.

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