Adverse effects of Plant Food Supplements and botanical preparation: Data collected during the EU project PlantLIBRA

2016 ◽  
Vol 258 ◽  
pp. S23-S24 ◽  
Author(s):  
Patrizia Restani ◽  
Alessandro Ceschi ◽  
Gianfranco Frigerio ◽  
Francesca Colombo ◽  
Saskia Lüde ◽  
...  
Keyword(s):  
Adverse Effects ◽  
Food Supplements ◽  
Plant Food ◽  
Eu Project ◽  
The Eu

scholarly journals Adverse Effects of Plant Food Supplements Self-Reported by Consumers in the PlantLIBRA Survey Involving Six European Countries

PLoS ONE ◽  
2016 ◽  
Vol 11 (2) ◽  
pp. e0150089 ◽  
Author(s):  
Patrizia Restani ◽  
Chiara Di Lorenzo ◽  
Alicia Garcia-Alvarez ◽  
Mihaela Badea ◽  
Alessandro Ceschi ◽  
...  
Keyword(s):  
Adverse Effects ◽  
Food Supplements ◽  
European Countries ◽  
Plant Food

scholarly journals Adverse effects of plant food supplements and botanical preparations: a systematic review with critical evaluation of causality

2015 ◽  
Vol 79 (4) ◽  
pp. 578-592 ◽  
Author(s):  
Chiara Di Lorenzo ◽  
Alessandro Ceschi ◽  
Hugo Kupferschmidt ◽  
Saskia Lüde ◽  
Elizabeth De Souza Nascimento ◽  
...  
Keyword(s):  
Systematic Review ◽  
Adverse Effects ◽  
Critical Evaluation ◽  
Food Supplements ◽  
Plant Food

scholarly journals Adverse Effects of Plant Food Supplements and Plants Consumed as Food: Results from the Poisons Centres-Based PlantLIBRA Study

2016 ◽  
Vol 30 (6) ◽  
pp. 988-996 ◽  
Author(s):  
Saskia Lüde ◽  
Sarah Vecchio ◽  
Sandra Sinno-Tellier ◽  
Aymeric Dopter ◽  
Harriet Mustonen ◽  
...  
Keyword(s):  
Adverse Effects ◽  
Food Supplements ◽  
Plant Food ◽  
Poisons Centres

Naldemedine: Peripherally Acting Opioid Receptor Antagonist for Treating Opioid-induced Adverse Effects

2020 ◽  
Vol 20 (31) ◽  
pp. 2830-2842
Author(s):  
Masanao Inagaki ◽  
Toshiyuki Kanemasa ◽  
Takaaki Yokota
Keyword(s):  
Adverse Effects ◽  
Adverse Events ◽  
Severe Pain ◽  
Lead Compound ◽  
Inhibitory Effects ◽  
Pharmacokinetic Profiles ◽  
Structure Activity ◽  
The Usa ◽  
Relationship Study ◽  
The Eu

Opioids are widely used for pain management in moderate-to-severe pain. However, opioids are associated with adverse events, such as constipation and emesis/vomiting. To reduce these undesired effects, a structure–activity relationship study of morphinan derivatives was conducted, and a promising lead compound with inhibitory effects on opioid receptors was obtained. Further improvement in the potency and pharmacokinetic profiles of the lead compound led to the discovery of naldemedine, which showed anti-constipation and anti-emetic effects against these adverse events that were induced by morphine without influencing morphine’s analgesic effect. Naldemedine was launched in Japan and the USA in 2017 and in the EU in 2019, for treating opioid-induced constipation.

A Review of Recent Patents (2016-2019) on Plant Food Supplements with Potential Application in the Treatment of Neurodegenerative and Metabolic Disorders

2020 ◽  
Vol 11 (2) ◽  
pp. 145-153 ◽  
Author(s):  
Rosalba Leuci ◽  
Leonardo Brunetti ◽  
Antonio Laghezza ◽  
Paolo Tortorella ◽  
Fulvio Loiodice ◽  
...  
Keyword(s):  
Metabolic Disorders ◽  
Food Supplements ◽  
Plant Food ◽  
Fortified Foods ◽  
Patent Review ◽  
Novel Strategy ◽  
Lifestyle Related Diseases ◽  
Near Future ◽  
Prevention And Therapy

In the near future, it is expected that the prevalence of illnesses related to the increasing life expectancies and quality of life, such as neurodegenerative diseases and cardiovascular diseases related to metabolic disorders, will soar to unprecedented levels, leading to high socioeconomic costs. To address this rising threat, natural products are emerging as a novel strategy for the prevention and therapy of these ages- and lifestyle-related diseases, thanks to their high marketability and few side effects. In this patent review, we summarize selected patents for food supplements, functional and fortified foods, filed from 2016 to 2019, categorizing them based on the biological activity of their components.

scholarly journals Efficient and Consumer-Centered Item Detection and Classification with a Multicamera Network at High Ranges

Sensors ◽  
2021 ◽  
Vol 21 (14) ◽  
pp. 4818
Author(s):  
Nils Mandischer ◽  
Tobias Huhn ◽  
Mathias Hüsing ◽  
Burkhard Corves
Keyword(s):  
Machine Learning ◽  
Shop Floor ◽  
Unsupervised Segmentation ◽  
User Friendliness ◽  
Industrial Environment ◽  
Machine Learning Methods ◽  
Eu Project ◽  
Detection And Localization ◽  
Industrial Context ◽  
The Eu

In the EU project SHAREWORK, methods are developed that allow humans and robots to collaborate in an industrial environment. One of the major contributions is a framework for task planning coupled with automated item detection and localization. In this work, we present the methods used for detecting and classifying items on the shop floor. Important in the context of SHAREWORK is the user-friendliness of the methodology. Thus, we renounce heavy-learning-based methods in favor of unsupervised segmentation coupled with lenient machine learning methods for classification. Our algorithm is a combination of established methods adjusted for fast and reliable item detection at high ranges of up to eight meters. In this work, we present the full pipeline from calibration, over segmentation to item classification in the industrial context. The pipeline is validated on a shop floor of 40 sqm and with up to nine different items and assemblies, reaching a mean accuracy of 84% at 0.85 Hz.

Deep renovation up to zero energy through Add-ons: the ABRACADABRA Project

2019 ◽  
Author(s):  
Annarita Ferrante ◽  
Fabrizio Ungaro ◽  
Giovanni Semprini ◽  
Lorna Dragonetti ◽  
Elettra Agliardi ◽  
...  
Keyword(s):  
Cost Effective ◽  
Urban Environments ◽  
Zero Energy ◽  
Urban Context ◽  
Building Stock ◽  
Existing Building ◽  
The Real Estate ◽  
International Projects ◽  
Eu Project ◽  
The Eu

<p>and international projects</p><p>various EU H2020 projects</p><p>Though housing is one of the most energy consumer sectors, it is currently extremely underestimated, because of a clear investment gap due to economic, social and legislative barriers. The EU project ABRACADABRA (Assistant Building to Retrofit, Adopt, Cure And Develop the Actual Buildings up to zeRo energy, Activating a market for deep renovation) is based on the idea that the real estate value increase given by the appropriate densification strategy in urban environments could be an opportunity to activate a market for deep energy renovation. To prove the effectiveness of the strategy more than 70 case studies throughout the EU cities have been assessed by means of a cost-effective analysis. Basing on the parametric variation of the different values involved (cost of construction, energy, etc.) the benefit of this strategy has been proved in the majority of the different building types and contexts.</p><p>More interestingly, the ABRA strategy has been simulated and tested outside Europe in order to verify its scalability and the possibility of considering other non-energy related benefits in the renovation of the existing building stock. A specific study on the NYC urban context has been conducted to effectively adapt the strategy and combine the global drivers of energy consumption reduction and CO<span>2</span> emission reduction with the local need of combating flood emergency and related flood-proofing measures.</p><p>The results reached by this work demonstrate how the energy retrofit trough add-ons reduces significantly the payback times of the investments, preserve soil consumption, while providing a extraordinary opportunity to enhance urban resiliency by challenging the local emergencies.</p>

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