L-type amino acid transporter 1 (LAT1): A new therapeutic target for canine mammary gland tumour

2013 ◽  
Vol 198 (1) ◽  
pp. 164-169 ◽  
Author(s):  
Shinya Fukumoto ◽  
Kiwamu Hanazono ◽  
Takahiro Komatsu ◽  
Hiroshi Ueno ◽  
Tsuyoshi Kadosawa ◽  
...  
Keyword(s):  
Mammary Gland ◽  
Amino Acid ◽  
Therapeutic Target ◽  
Amino Acid Transporter ◽  
Acid Transporter ◽  
Canine Mammary Gland ◽  
Gland Tumour

scholarly journals L-Type Amino Acid Transporter 1 (LAT1) Expression in Canine Mammary Gland Tumors

2013 ◽  
Vol 75 (4) ◽  
pp. 431-437 ◽  
Author(s):  
Shinya FUKUMOTO ◽  
Kiwamu HANAZONO ◽  
Takahiro KOMATSU ◽  
Hidetomo IWANO ◽  
Tsuyoshi KADOSAWA ◽  
...  
Keyword(s):  
Mammary Gland ◽  
Amino Acid ◽  
Amino Acid Transporter ◽  
Mammary Gland Tumors ◽  
Acid Transporter ◽  
Canine Mammary Gland

Deletion of the amino acid transporter Slc6a14 suppresses tumour growth in spontaneous mouse models of breast cancer

2015 ◽  
Vol 469 (1) ◽  
pp. 17-23 ◽  
Author(s):  
Ellappan Babu ◽  
Yangzom D. Bhutia ◽  
Sabarish Ramachandran ◽  
Jaya P. Gnanaprakasam ◽  
Puttur D. Prasad ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Amino Acid ◽  
Mouse Models ◽  
Therapeutic Target ◽  
Tumour Growth ◽  
Mammalian Target Of Rapamycin ◽  
Amino Acid Transporter ◽  
Mtor Pathway ◽  
Target Of Rapamycin ◽  
Acid Transporter

Deletion of the amino acid transporter Slc6a14 in mice suppresses tumour growth in spontaneous models of breast cancer via interference with mammalian target of rapamycin (mTOR) pathway; this indicates an obligatory role for SLC6A14 in breast cancer, highlighting its potential as a therapeutic target.

scholarly journals Prolactin and the dietary protein/carbohydrate ratio regulate the expression of SNAT2 amino acid transporter in the mammary gland during lactation

2015 ◽  
Vol 1848 (5) ◽  
pp. 1157-1164 ◽  
Author(s):  
Laura A. Velázquez-Villegas ◽  
Adriana M. López-Barradas ◽  
Nimbe Torres ◽  
Rogelio Hernández-Pando ◽  
Juan Carlos León-Contreras ◽  
...  
Keyword(s):  
Mammary Gland ◽  
Amino Acid ◽  
Dietary Protein ◽  
Amino Acid Transporter ◽  
Acid Transporter

scholarly journals Efficacy of system l amino acid transporter 1 inhibition as a therapeutic target in esophageal squamous cell carcinoma

2016 ◽  
Vol 107 (10) ◽  
pp. 1499-1505 ◽  
Author(s):  
Yasuhiro Ohshima ◽  
Kyoichi Kaira ◽  
Aiko Yamaguchi ◽  
Noboru Oriuchi ◽  
Hideyuki Tominaga ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Amino Acid ◽  
Esophageal Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Therapeutic Target ◽  
Amino Acid Transporter ◽  
System L ◽  
Acid Transporter

scholarly journals Cationic amino acid transporter PQLC 2 is a potential therapeutic target in gastric cancer

2019 ◽  
Vol 110 (4) ◽  
pp. 1453-1463 ◽  
Author(s):  
Yun‐Ji Jeung ◽  
Kyeong Lee ◽  
Hyo Jin Lee ◽  
Eunah Kim ◽  
Myung Jin Son ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Amino Acid ◽  
Therapeutic Target ◽  
Amino Acid Transporter ◽  
Cationic Amino Acid Transporter ◽  
Potential Therapeutic Target ◽  
Cationic Amino Acid ◽  
Acid Transporter

Increased expression of an amino acid transporter LAT1 in healing of acetic acid-induced chronic gastric ulcer in rats

2001 ◽  
Vol 120 (5) ◽  
pp. A153-A153
Author(s):  
S MIYAMOTO ◽  
K KATO ◽  
Y ISHII ◽  
S ASAI ◽  
T NAGAISHI ◽  
...  
Keyword(s):  
Acetic Acid ◽  
Gastric Ulcer ◽  
Amino Acid ◽  
Amino Acid Transporter ◽  
Chronic Gastric Ulcer ◽  
Acid Transporter
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