Helical computed tomography accurately reports urinary stone composition using attenuation values: in vitro verification using high-resolution micro-computed tomography calibrated to fourier transform infrared microspectroscopy

Urology ◽  
2004 ◽  
Vol 63 (5) ◽  
pp. 828-833 ◽  
Author(s):  
Chad A Zarse ◽  
James A McAteer ◽  
Mark Tann ◽  
Andre J Sommer ◽  
Samuel C Kim ◽  
...  
Proceedings ◽  
2019 ◽  
Vol 42 (1) ◽  
pp. 19 ◽  
Author(s):  
Marianna Portaccio ◽  
Sonia Errico ◽  
Teresa Chioccarelli ◽  
Gilda Cobellis ◽  
Maria Lepore

Fourier-Transform Infrared micro-spectroscopy (µFT-IR) was used for an in vitro investigation on spermatozoa (SPZ) samples separately collected from caput and cauda of mouse epididymis. SPZ are characterized by deep biochemical changes during the transit along the epididymis and they can constitute ideal candidates for a µFT-IR investigation, thanks to the ability of this technique in analyzing cells at a molecular level. Appreciable differences were reported in the infrared spectra from caput and cauda SPZ, and biochemical changes in protein, nucleic acid, lipid, and carbohydrate content of cells were evidenced. The present investigation indicates that µFT-IR can constitute a valuable tool for monitoring, in an easy and fast way, the changes suffered by SPZ during the transit along the epididymis.


2003 ◽  
Vol 31 (1) ◽  
pp. 1-5 ◽  
Author(s):  
A Demirel ◽  
S Suma

The composition of urinary stones was predicted on the basis of the differences in their Hounsfield unit (HU) densities as detected by in vivo non-contrast helical computed tomography (NCHCT). A total of 87 stones, which had been obtained from patients admitted to the emergency department with acute flank pain, were analysed biochemically. These stones had been visualized by NCHCT before spontaneous passage, ureteroscopic extraction or surgical removal, and their HU densities had been recorded. The HU densities of the stones were compared with the results of biochemical analysis. The mean HU densities of the stones composed of calcium oxalate ( n = 54), struvite ( n = 19) and uric acid ( n = 14) were 812 ± 135, 614 ± 121 and 413 ± 143, respectively. The differences between the mean HU densities of these three stone types were statistically significant. This initial clinical study demonstrated that in vivo NCHCT analysis may be used to predict the composition of urinary stones.


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