Does Transurethral Resection of Prostate (TURP) Affect Outcome in Patients Who Subsequently Develop Prostate Cancer?

Urology ◽  
2008 ◽  
Vol 71 (5) ◽  
pp. 938-941 ◽  
Author(s):  
David J. D'Ambrosio ◽  
Karen Ruth ◽  
Eric M. Horwitz ◽  
David Y.T. Chen ◽  
Alan Pollack ◽  
...  
2020 ◽  
pp. 79-80
Author(s):  
Alfy Ann George ◽  
Anitha Das P.H ◽  
I. Praseeda ◽  
Baby Mathew

Aim: To identify the rate of incidental prostate cancer in patients undergone Transurethral resection of prostate(TURP) over a period of 5 years in our center. Methods: A Retrospective review was conducted using Histopathological department database on all TURP specimens over a period of 5 years from January 2015 to December 2019. Results: Out of 570 cases of TURP during our study period, 1.9% had incidental prostate cancer. Most of these positive cases had a Gleasons score of 10, which represent poorly differentiated Adenocarcinoma. Conclusion: The value of pathologic review of TURP specimens is limited but a detailed review helps to reduce under detection of prostate cancer.


2019 ◽  
Vol 13 (6) ◽  
pp. 451-453
Author(s):  
Alain Mwamba Mukendi ◽  
Sean Doherty ◽  
Lungile Ngobese

In bilharzia-endemic areas, schistosomiasis is a common infection. Prostate cancer is also a common urological condition affecting people in both bilharzia and non-bilharzia-endemic areas. The association of these familiar conditions is infrequent and the relationship between these entities still controversial. We are adding to the literature a rare case of prostatic bilharzia on needle biopsy, and the subsequent finding of prostatic adenocarcinoma on transurethral resection of prostate specimens. Level of evidence: 4


2015 ◽  
Vol 26 (2) ◽  
pp. S58
Author(s):  
Chih-Te Lin ◽  
Chen-Pang Hou ◽  
Yu-Hsiang Lin ◽  
Ke-Hung Tsui ◽  
Phei-Lang Chang ◽  
...  

1970 ◽  
Vol 1 (2) ◽  
Author(s):  
Chenglin Huang

Objective: To investigate the feasibility of transurethral resection of prostate and the treatment of advanced prostate cancer and bladder outlet infarction, and to analyze the therapeutic effect. Methods: 34 patients with advanced prostate cancer admitted in our hospital from April 2014 to April 2014 were divided into control group (17 cases) with routine endocrine therapy. The study group (17 cases) underwent urethral resection surgery Combined with endocrine therapy, through the relevant indicators of prostate treatment were observed to explore the two groups of patients with therapeutic effect. Results: According to the related indexes of prostate treatment, the treatment effect of the study group was significantly better than that of the control group, and the data of the two groups were statistically significant (P<0.05). Conclusion: The treatment of advanced prostate cancer patients with endocrine combined with transurethral resection of the prostate can effectively treat the symptoms of bladder outlet infarction and improve the quality of life of patients. It has certain value in clinical treatment.


Author(s):  
Anuja Sharma ◽  
Mahima Sharma ◽  
Shivani Gandhi ◽  
Arvind Khajuria ◽  
K. C. Goswami

Background: Prostatic diseases like inflammation, benign prostatic hyperplasia and tumors are important causes of mortality and morbidity in males. The incidence of these lesions increases with advancing age. The second most common cancer among males is prostate cancer, next to lung cancer worldwide. Transurethral resection of prostate (TURP) is most frequently preformed surgical procedure in the clinical practice. The purpose of the study is to evaluate histomorphological spectrum of prostate lesions in TURP specimen with focus on premalignant lesions and incidental carcinomas.Methods: The present study includes 245 cases of TURP specimen from January 2015 to December 2016 received in the post graduate department of pathology, ASCOMS and Hospital. H and E stained sections were examined. The relevant clinical details pertaining to age, clinical complaints and microscopic details were analysed and compared with other similar studies.Results: Of the total 245 TURP specimen, 223 (91.02%) were of nodular hyperplasia, 14 (5.71%) were of prostatic intraepithelial neoplasia and 8 (3.26%) cases were malignant. Benign hyperplasia of prostate (BHP) alone accounted for 91.02% of TURP specimen. Less frequent findings were granulomatous prostatitis in 3.70% and atypical adenomatous hyperplasia (1.22%). All the 8 cases of prostate cancer were incidental carcinoma, 5 of which were poorly differentiated and 3 were moderately differentiated adenocarcinoma.Conclusions: The present study showed that non-neoplastic lesions of prostate are more common than neoplastic ones. The most frequently encountered prostatic lesion was BHP, commonly seen in the age group of 61-70 years. The malignant lesions were common among the males of more than 60 years. TURP can be helpful in early identification of premalignant lesions and incidental prostate cancer which can improve the treatment outcome of patients.


2020 ◽  
Vol 3 (2) ◽  
pp. e22-e30
Author(s):  
Masaru Morita ◽  
Akira Morita ◽  
Takeshi Matsuura

Background and ObjectivesMinimally invasive methods are expected to avoid the risk of overtreatment and overtreatment of radical therapy to manage the increased number of patients with low-volume, low-grade localized prostate cancer. Based on our experience of radical transurethral resection of prostate cancer (TURPCa) as a radical treatment, we studied the efficacy and safety of focal TURPCa as a focal therapy for patients with localized prostate cancer. Materials and MethodsWe performed focal TURPCa in 49 patients during the period from July 2007 to August 2016 and followed them with prostate-specific antigen (PSA) testing for the mean period of 68.0 months. We selected the patient as a candidate for the study if the biopsy revealed that cancer foci were limited in one lobe, or the foci were several or less even found in both lobes. Standard TURP was followed by further resection and fulguration of the peripheral zone where cancer was considered to exist. We selected one of our three methods of focal TURPCa as follows: one lobe radical TURPCa, radical resection of the affected lobe with unaffected lobe being resected less vigorously; nerve-sparing radical TURPCa, radical resection of both lobes except for the posterolateral part of the prostate; target radical TURPCa, radical resection of the cancer focus and the surrounding prostate when the target is suggested single. ResultsTwelve patients were in the low-risk group (D’Amico), 29 in the intermediate-risk group, and 8 in the high-risk group. Pathological stages were as follows: pT0, three cases; pT2a-b, 17 cases; pT2c, 29 cases. The preoperative PSA of 6.15±2.73 ng/mL (mean±SD) dropped to 0.172±0.283 ng/mL postoperatively. PSA failure occurred in only two patients (4.1%). Incontinence did not develop and erectile function was preserved in eight (44.4%) of the 18 potent patients. The most frequent complication was bladder neck contracture (20.4%). Other complications included acute epididymitis (8.1%), bladder tamponade (2.0%). No patients died of prostate cancer. ConclusionsThough the final assessment of efficacy will require long-term follow-up results with more cases, we may think focal TURPCa can be another treatment option as a focal therapy for localized prostate cancer.


2014 ◽  
Vol 95 (2) ◽  
pp. 216-219
Author(s):  
M B Pryanichnikova ◽  
R S Nizamova ◽  
E S Gubanov ◽  
A A Zimichev ◽  
E A Boryaev

Aim. To assess the rate and reasons for urological complications of subtotal transurethral resection of prostate performed prior to high-intensity focused ultrasound. Methods. The study included 101 patients with localized prostate cancer treated by high-intensity focused ultrasound. Two groups of patients were allocated. Patients, who did not undergo transurethral resection of prostate prior to high-intensity focused ultrasound, were included in group 1 (21 patients). Second group included patients in whom subtotal transurethral resection of prostate was performed prior to high-intensity focused ultrasound to decrease anteroposterior diameter of the prostate and urethral canal compression. The impact of treatment tactics on complications rate was defined by factor analysis. Results. Early post-surgical complications were rare, complications mostly occurred at late period. The most frequent, severe and poorly controlled complications included urinary incontinence [58 (57.8%) patients] and urethral stricture [30 (29.7%) patients]. Most of complications were registered in second group of patients compared to the first: first group - in 10 (12.5%) of cases, second group - in 77 (95.0%) of cases. Urinary incontinence was observed in 7 (33.3%) patients and urethral stricture - in 4 (19%) of patients in the first group; in 51 (63.7%) and 26 (32.5%) patients in the second group respectively; the difference was statistically significant. Conclusion. Comparative analysis of different approaches to treatment of localized prostate cancer using high-intensity focused ultrasound revealed that subtotal transurethral resection of prostate performed prior to high-intensity focused ultrasound significantly increases the risk for developing urinary incontinence and urethral strictures.


2018 ◽  
Author(s):  
Dan B Ellis ◽  
Anton Wintner

Today, urologists care for patients who have benign diseases of the ureter, bladder, and urethra such as kidney or bladder stones as well as patients with malignancies such as bladder tumors or prostate cancer. Furthermore, as technology improves, larger, more invasive operations are being replaced by minimally invasive procedures. Patient comorbidities and need for anticoagulant medications have increased in quantity and scope. Therefore, anesthetic techniques, which have historically relied heavily on neuraxial anesthesia, have been forced to evolve to safely care for these progressively ill patients. Thus, a number of historical approaches to urologic procedures are no longer applicable. Therefore, an understanding of the type and scope of the operation being performed as well as an understanding of the patient’s own comorbidities is key to safely caring for the modern urologic patient. This review contains 5 figures, 5 tables, and 30 references. Key Words: bladder, cystectomy, hyponatremia, irrigating fluids, lithotripsy, prostate, transurethral resection of prostate, ureter, urethra


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