scholarly journals Efficient replication and strong induction of innate immune responses by H9N2 avian influenza virus in human dendritic cells

Virology ◽  
2014 ◽  
Vol 471-473 ◽  
pp. 38-48 ◽  
Author(s):  
Veera Westenius ◽  
Sanna M. Mäkelä ◽  
Thedi Ziegler ◽  
Ilkka Julkunen ◽  
Pamela Österlund
2000 ◽  
Vol 11 (16) ◽  
pp. 2207-2218 ◽  
Author(s):  
Isolde Strobel ◽  
Markus Krumbholz ◽  
Annette Menke ◽  
Erich Hoffmann ◽  
P. Rod Dunbar ◽  
...  

Diabetes ◽  
2010 ◽  
Vol 59 (5) ◽  
pp. 1182-1191 ◽  
Author(s):  
B. M. Schulte ◽  
M. Kramer ◽  
M. Ansems ◽  
K. H. W. Lanke ◽  
N. van Doremalen ◽  
...  

2020 ◽  
Vol 51 (1) ◽  
Author(s):  
Jing Yang ◽  
Xinmei Huang ◽  
Yuzhuo Liu ◽  
Dongmin Zhao ◽  
Kaikai Han ◽  
...  

Abstract MicroRNA (miRNA) plays a key role in virus-host interactions. Here, we employed deep sequencing technology to determine cellular miRNA expression profiles in chicken dendritic cells infected with H9N2 avian influenza virus (AIV). A total of 66 known and 36 novel miRNAs were differently expressed upon H9N2 infection, including 72 up-regulated and 30 down-regulated miRNAs. Functional analysis showed that the predicted targets of these miRNAs were significantly enriched in several pathways including endocytosis, notch, lysosome, p53, RIG-I-like and NOD-like receptor signaling pathways. These data provide valuable information for further investigating the roles of miRNA in AIV pathogenesis and host defense response.


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