HIPEC in ovarian cancer: The first case control study in Mexican patients with 10-year follow-up

2020 ◽  
Vol 159 ◽  
pp. 152
Author(s):  
J.M. Medina ◽  
A.B. Gonzalez-Valdes ◽  
F. Morales-Vasquez ◽  
F. Rivera-Buendia ◽  
H.N. López-Basave ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Case Control Study ◽  
Case Control ◽  
First Case ◽  
Control Study ◽  
Mexican Patients

scholarly journals 425 Hipec in ovarian cancer: the first case-control study in mexican patients

2020 ◽  
Author(s):  
Juan Manuel Medina-Castro ◽  
Arely Gonzlez ◽  
Flavia Morales ◽  
Maria Antonia Morales
Keyword(s):  
Ovarian Cancer ◽  
Case Control Study ◽  
Case Control ◽  
First Case ◽  
Control Study ◽  
Mexican Patients

Laparoscopy compared with laparotomy for comprehensive surgical staging of early ovarian cancer: Results of a retrospective multicenter case-control study.

2020 ◽  
Vol 38 (15_suppl) ◽  
pp. 6067-6067
Author(s):  
Julia Caroline Radosa ◽  
Marc P Radosa ◽  
Pauline Mertke ◽  
Marie-Luise Hugo ◽  
Christoph Georg Radosa ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Case Control Study ◽  
Case Control ◽  
Surgical Staging ◽  
Control Group ◽  
Increased Risk ◽  
Duration Of Surgery ◽  
Early Ovarian Cancer ◽  
Control Study

6067 Background: The objective of this study was to compare laparoscopy and laparotomy for comprehensive surgical staging of early ovarian cancer in terms of efficacy and oncologic safety. Methods: Patients who had laparoscopic staging for early stage (I/II) ovarian cancer between 01/2000 and 10/2018 at the participating sites (Gynecologic comprehensive cancer centers with respective expertise in minimal invasive surgery) were included in this retrospective case-control study. The control group consisted of all patients treated via laparotomy during the study period. Clinical data were abstracted from medical record and recent follow up information were obtained. Comparisons were made between patients regarding surgical parameters and oncologic outcome and multivariate models were used to identify factors independently associated with disease recurrence. Results: Among 313 patients, staging was performed via laparoscopy in 208 (66 %) patients and via laparotomy in 105 (34 %) patients. Patients staged laparoscopically were younger (median 52 (15-86) vs. 59 (17-92) vears, p≤0.01) and had a lower BMI (24.4 (16.5-46.8) vs. 26 (15.5-53.8), p≤0.01). Regarding surgical parameters, duration of surgery was longer (291 (159-778) vs. 277 (159-690) minutes, p≤0.01), postoperative hospitalization was shorter (7 (0-27) vs. 9 (0-92) days, p≤0.01) and postoperative complications were lower in the laparoscopy group. On univariate analysis there were no differences in rates of tumor stage according to FIGO, intraoperative rupture of ovarian cysts (14 % vs. 13 %, p=0.87), number of lymph nodes removed (24 (0-89) vs. 22 (0-96), p=0.81) or any recurrence of disease (14 % vs. 16 %, p=0.52). At a median follow-up of 46 months (0-227), there were no differences in DFS and OS by surgical technique (5yr DFS 82 % (SE 0.04) vs. 83 % (SE 0.05), p=0.43; OS 91 % (SE 0.03) vs. 87 % (SE 0.04), p=0.87). On multivariate analysis route of surgery was not associated with an increased risk of recurrence. Conclusions: According to this preliminary analysis, laparoscopic surgical staging in patients with early ovarian cancer seems to be adequate and safe, but a longer follow-up and prospective data are needed to enhance evidence on oncologic outcomes.

scholarly journals The pandemic of Salmonella Enteritidis phage type 4 reaches Utah: a complex investigation confirms the need for continuing rigorous control measures

2000 ◽  
Vol 125 (1) ◽  
pp. 1-8 ◽  
Author(s):  
J. SOBEL ◽  
A. B. HIRSHFELD ◽  
K. McTIGUE ◽  
C. L. BURNETT ◽  
S. ALTEKRUSE ◽  
...  
Keyword(s):  
Risk Factors ◽  
Salmonella Enteritidis ◽  
Case Control Study ◽  
Phage Type ◽  
Case Control ◽  
Control Measures ◽  
Complex Investigation ◽  
First Case ◽  
Control Study

In 1995, Salmonella Enteritidis (SE) cases in the state of Utah increased fivefold. Isolates were identified as phage type 4 (PT4). Risk factors and sources of infection were investigated in two case-control studies, a traceback of implicated foods, and environmental testing. Forty-three patients with sporadic infections and 86 controls were included in a case-control study of risk factors for infection. A follow-up case-control study of 25 case and 19 control restaurants patronized by case and control patients examined risks associated with restaurant practices. In the first case-control study, restaurant dining was associated with illness (P = 0·002). In the follow-up case-control study, case restaurants were likelier to use > 2000 eggs per week (P < 0·02), to pool eggs (P < 0·05), and to use eggs from cooperative ‘A’ (P < 0·009). Eggs implicated in separately investigated SE PT4 outbreaks were traced to cooperative ‘A’, and SE PT4 was cultured from one of the cooperative's five local farms. We conclude that SE PT4 transmitted by infected eggs from a single farm caused a fivefold increase in human infections in Utah.

scholarly journals First Case-Control Study of Intestinal Parasites in Follow-up Schizophrenia Patients: Are We Overlooking the Role of These Agents?

2021 ◽  
Vol 22 (3) ◽  
pp. 213-217
Author(s):  
Zeynep Yalnız ◽  
Ersel Bulu ◽  
Yasin Kavla ◽  
Burcu Sapmaz ◽  
Reyhan Çalışkan ◽  
...  
Keyword(s):  
Case Control Study ◽  
Intestinal Parasites ◽  
Case Control ◽  
First Case ◽  
Control Study

scholarly journals Determinants of short birth interval among women in South Gondar, Ethiopia: community-based unmatched case-control study

2021 ◽  
Vol 79 (1) ◽  
Author(s):  
Gedefaye Nibret Mihretie ◽  
Fentahun Yenealem Beyene ◽  
Bekalu Getnet Kassa ◽  
Alemu Degu Ayele ◽  
Tewachew Muche Liyeh ◽  
...  
Keyword(s):  
Antenatal Care ◽  
Birth Interval ◽  
Case Control Study ◽  
Birth Spacing ◽  
Case Control ◽  
Community Based ◽  
Short Birth Interval ◽  
South Gondar ◽  
Control Study

Abstract Background The effect of short birth interval on socio-economic, negative maternal and child health outcomes remains common in developing countries. This study aimed to assess determinants of short birth interval among reproductive age women, who gave birth in health institution for last six-month in South Gondar, Ethiopia 2019. Methods Community-based unmatched case control study design was conducted from February 1 to March 30, 2019. Sample size of 150 was included by simple random sampling technique. The data was collected by semi-structured and pre-tested face to face interviewer-administered questionnaire from selected respondent. The collected data was entered with Epi-Data version 3.1 and analyzed by using SPSS version 23 software. Bivariate and multivariable analyses were used to examine the association. Odds ratio, 95% CI and P-value < 0.05 were used to determine the statistical association. Result The mean age of the respondents was 32.42 (SD ± 5.14) and 35.12 (SD ± 5.86) for cases and controls, respectively. Mothers not used contraceptives (AOR = 6.29, 95% CI (1.95, 20.24)), participants who had ≤2 alive children (AOR = 5.57, 95% CI (1.47, 21.13)), mothers who breast fed less than 24 months (AOR = 3.42, 95% CI (1.38, 8.46)), husband decision on contraceptives utilization (AOR = 2.69,95% CI (1.05,6.88)) and mothers who did not have history of antenatal care follow up (AOR = 3.52, 95% CI (1.27, 9.75)) were associated with short birth interval. Conclusion The optimum birth spacing plays a vital role in decreasing fertility and the morbidity and mortality of mothers and children. Thus, providing health information on the benefit of breast feeding, follow-up of antenatal care during pregnancy, use of contraceptives after delivery and encouraging mothers to make decisions about their own health and use of contraceptives to optimize birth spacing for rural communities.

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