I. Weight loss, nutrient intake, and subjective evaluation: Balanced low-calorie vs. high-protein-low-carbohydrate reducing diets 1

1974 ◽  
Vol 64 (1) ◽  
pp. 47-51 ◽  
Author(s):  
BONNIE S. WORTHINGTON ◽  
LYNDA E. TAYLOR
Biomedicines ◽  
2021 ◽  
Vol 10 (1) ◽  
pp. 16
Author(s):  
Rohia Alili ◽  
Eugeni Belda ◽  
Odile Fabre ◽  
Véronique Pelloux ◽  
Nils Giordano ◽  
...  

Background: Dietary intervention is a cornerstone of weight loss therapies. In obesity, a dysbiotic gut microbiota (GM) is characterized by high levels of Bacteroides lineages and low diversity. We examined the GM composition changes, including the Bacteroides 2 enterotype (Bact2), in a real-world weight loss study in subjects following a high-protein hypocaloric diet with or without a live microorganisms (LMP) supplement. Method: 263 volunteers were part of this real-world weight loss program. The first phase was a high-protein low-carbohydrate calorie restriction diet with or without LMP supplements. Fecal samples were obtained at baseline and after 10% weight loss for 163 subjects. Metagenomic profiling was obtained by shotgun sequencing. Results: At baseline, the Bact2 enterotype was more prevalent in subjects with aggravated obesity and metabolic alterations. After weight loss, diversity increased and Bact2 prevalence decreased in subjects with lower GM diversity at baseline, notably in LMP consumers. Significant increases in Akkermansia muciniphila and Parabacteroides distasonis and significant decreases of Eubacterium rectale, Streptococcus thermophilus and Bifidobacterial lineages were observed after weight loss. Conclusion: Baseline microbiome composition is associated with differential changes in GM diversity and Bact2 enterotype prevalence after weight loss. Examining these signatures could drive future personalized nutrition efforts towards more favorable microbiome compositions.


2007 ◽  
Vol 55 (1) ◽  
pp. S95
Author(s):  
M. Allian-Sauer ◽  
W. H. Capell ◽  
J. P. Sutherland ◽  
P. Wolfe ◽  
N. D. Talley ◽  
...  

2006 ◽  
Vol 20 (4) ◽  
Author(s):  
Julia MW Wong ◽  
Amin Esfahani ◽  
Cyril WC Kendall ◽  
David JA Jenkins

2012 ◽  
Vol 71 (2) ◽  
pp. 339-349 ◽  
Author(s):  
Alexandra M. Johnstone

Dietary strategies that can help reduce hunger and promote fullness are beneficial for weight control, since these are major limiting factors for success. High-protein (HP) diets, specifically those that maintain the absolute number of grams ingested, while reducing energy, are a popular strategy for weight loss (WL) due to the effects of protein-induced satiety to control hunger. Nonetheless, both the safety and efficacy of HP WL diets have been questioned, particularly in combination with low-carbohydrate advice. Nonetheless, for short-to-medium-term intervention studies (over several months), increasing the energetic contribution of protein does appear effective. The effects of HP diets on appetite, bone health, renal function, blood pressure, cardiovascular bio-markers, antioxidant status, gut health and psychological function are discussed. Further research is warranted to validate the physiological effects of HP diets over longer periods of time, including studies that modify the quality of macronutrients (i.e. the type of carbohydrate, fat and protein) and the interaction with other interventions (e.g. exercise and dietary supplements).


2015 ◽  
Vol 62 (2) ◽  
pp. 162-174
Author(s):  
Razvan Vasilescu ◽  

It is well known the role of diet in the management of overweight and obese type 2 diabetic patients. Even a modest weight loss (5% to 10% of total body weight) is associated with improvements of cardiovascular risk factors. The traditional recommendations regarding the intake of macronutrients are: carbohydrate intake 45% to 65% of total energy, a total fat intake ≤ 35% of total energy (with reduction of saturated and trans fat intake and increase monounsaturated fatty acids intake) and protein intake 15% to 20% of total energy. The recent guidelines recommend increased flexibility in macronutrient composition. In this article I present different dietary patterns (such as low carbohydrate diets, high protein diets, low calorie diets, very low calorie diets and Mediterranean diet) used in the management of type 2 diabetic patients, their effects on short-term outcomes as well as on long-term outcomes. Energy restriction is required for weight loss. In short-term trials high-protein, low-carbohydrate diets are more favorable for weight loss than traditional high-carbohydrate, low-fat diets. Very important in weight loss and metabolic control are the adherence to a diet and pharmacotherapy. Recently probiotic and prebiotic have been proposed as a new treatment strategy.


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