Skeletal effects of orthovoltage and megavoltage therapy following treatment of nephroblastoma

1982 ◽  
Vol 33 (6) ◽  
pp. 601-613 ◽  
Author(s):  
Robert Smith ◽  
John K. Davidson ◽  
Gerald E. Flatman
Keyword(s):  
Skeletal Effects ◽  
Megavoltage Therapy

Coronary Heart Disease-a Possible Risk in Megavoltage Therapy?

2009 ◽  
Vol 203 (1-6) ◽  
pp. 237-239 ◽  
Author(s):  
Sten Rasmussen ◽  
Martin Døssing ◽  
Sven Walbom-Jørgensen
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Megavoltage Therapy

scholarly journals Denosumab Discontinuation and the Rebound Phenomenon: A Narrative Review

2021 ◽  
Vol 10 (1) ◽  
pp. 152
Author(s):  
Athanasios D. Anastasilakis ◽  
Polyzois Makras ◽  
Maria P. Yavropoulou ◽  
Gaia Tabacco ◽  
Anda Mihaela Naciu ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Bone Resorption ◽  
Negative Effects ◽  
Mineral Density ◽  
Skeletal Effects ◽  
Rebound Phenomenon ◽  
Pre Treatment ◽  
Patients Experience ◽  
Multiple Vertebral Fractures ◽  
Optimal Regimen

Denosumab is a potent antiresorptive agent that substantially increases bone mineral density and reduces fracture rates at all skeletal sites for as long as it is administered. However, its favorable skeletal effects reverse quickly upon its discontinuation, because of a vast increase of osteoclast number and activity, which leads to a subsequent profound increase of bone turnover above pre-treatment values, a phenomenon commonly described as “rebound phenomenon”. More importantly, most patients experience rapid, profound bone loss due to this burst of bone resorption that may lead in a minority of these patients to occurrence of fractures, especially multiple vertebral fractures. Therefore, subsequent antiresorptive treatment is mandatory, although the optimal regimen is yet to be clarified. In the present review, we outline what is currently known regarding the negative effects of denosumab discontinuation on different aspects of bone status, the factors that may affect them, and strategies to prevent them.

scholarly journals Skeletal Effects of the Saturated 3-Thia Fatty Acid Tetradecylthioacetic Acid in Rats

PPAR Research ◽  
2011 ◽  
Vol 2011 ◽  
pp. 1-10 ◽  
Author(s):  
Astrid Kamilla Stunes ◽  
Irene Westbroek ◽  
Reidar Fossmark ◽  
Rolf Kristian Berge ◽  
Janne Elin Reseland ◽  
...  
Keyword(s):  
Whole Body ◽  
Sham Operation ◽  
Peroxisome Proliferator ◽  
Mineral Density ◽  
Femoral Bone Mineral Density ◽  
Peroxisome Proliferator Activated Receptor ◽  
Trabecular Thickness ◽  
Tetradecylthioacetic Acid ◽  
Femoral Metaphysis ◽  
Skeletal Effects

This study explores the skeletal effects of the peroxisome proliferator activated receptor (PPAR)pan agonist tetradecylthioacetic acid (TTA). Rats, without (Study I) and with ovariectomy (OVX) or sham operation (Study II), were given TTA or vehicle daily for 4 months. Bone markers in plasma, whole body and femoral bone mineral density and content (BMD and BMC), and body composition were examined. Histomorphometric and biomechanical analyses (Study I) and biomechanical and μCT analyses (Study II) of the femur were performed. Normal rats fed TTA had higher femoral BMD and increased total and cortical area in femur compared to controls. The ovariectomized groups had decreased BMD and impaired microarchitecture parameters compared to SHAM. However, the TTA OVX group maintained femoral BMC, trabecular thickness in the femoral head, and cortical volume in the femoral metaphysis as SHAM. TTA might increase BMD and exert a light preventive effect on estrogen-related bone loss in rats.

Skeletal effects of early treatment of Class III malocclusion with maxillary expansion and face-mask therapy

1998 ◽  
Vol 113 (3) ◽  
pp. 333-343 ◽  
Author(s):  
Tiziano Baccetti ◽  
Jean S. McGill ◽  
Lorenzo Franchi ◽  
James A. McNamara ◽  
Isabella Tollaro
Keyword(s):  
Early Treatment ◽  
Face Mask ◽  
Class Iii ◽  
Class Iii Malocclusion ◽  
Maxillary Expansion ◽  
Skeletal Effects

scholarly journals Skeletal alterations associated with the use of bonded rapid maxillary expansion appliance

2011 ◽  
Vol 22 (4) ◽  
pp. 334-339 ◽  
Author(s):  
Moara de Rossi ◽  
Andiara de Rossi ◽  
Jorge Abrão
Keyword(s):  
Rapid Maxillary Expansion ◽  
Growth Patterns ◽  
Facial Growth ◽  
Maxillary Expansion ◽  
Skeletal Changes ◽  
End Of Treatment ◽  
The Face ◽  
Vertical Changes ◽  
Skeletal Effects ◽  
Cephalometric Study

Bonded maxillary expansion appliances have been suggested to control increases in the vertical dimension of the face after rapid maxillary expansion (RME). However, there is still no consensus in the literature about its real skeletal effects. The purpose of this prospective study was to evaluate, longitudinally, the vertical and sagittal cephalometric alterations after RME performed with bonded maxillary expansion appliance. The sample consisted of 26 children, with a mean age of 8.7 years (range: 6.9-10.9 years), with posterior skeletal crossbite and indication for RME. After maxillary expansion, the bonded appliance was used as a fixed retention for 3.4 months, being replaced by a removable retention subsequently. The cephalometric study was performed onto lateral radiographs, taken before treatment was started, and again 6.3 months after removing the bonded appliance. Intra-group comparison was made using paired t test. The results showed that there were no significant sagittal skeletal changes at the end of treatment. There was a small vertical skeletal increase in five of the eleven evaluated cephalometric measures. The maxilla displaced downward, but it did not modify the facial growth patterns or the direction of the mandible growth. Under the specific conditions of this research, it may be concluded that RME with acrylic bonded maxillary expansion appliance did promote signifciant vertical or sagittal cephalometric alterations. The vertical changes found with the use of the bonded appliance were small and probably transitory, similar to those occurred with the use of banded expansion appliances.

Megavoltage Therapy in Patients with Aneurysmal Bone Cysts

Radiology ◽  
1976 ◽  
Vol 118 (2) ◽  
pp. 421-424 ◽  
Author(s):  
Richard D. Marks ◽  
Hugh J. Scruggs ◽  
Keene M. Wallace ◽  
Jimmy O. Fenn
Keyword(s):  
Bone Cysts ◽  
Aneurysmal Bone Cysts ◽  
Megavoltage Therapy
Sign in / Sign up

Export Citation Format

Share Document