The NF-KB mediated expression of inos in intestinal epithelial cells is dependent on the cellular redox status

2000 ◽  
Vol 118 (4) ◽  
pp. A592
Author(s):  
Gerard Dijkstra ◽  
Manon Homan ◽  
Harry van Goor ◽  
Mariska Geuken ◽  
Alie D. Jager ◽  
...  
2019 ◽  
Vol 2019 ◽  
pp. 1-6 ◽  
Author(s):  
Xiangbing Mao ◽  
Qing Yang ◽  
Daiwen Chen ◽  
Bing Yu ◽  
Jun He

As a kind of antibacterial and antifungal preservative, benzoic acid is widely used in foods and feeds. Recently, many studies showed that it could improve the growth and health, which should, at least partially, be derived from the promotion of gut functions, including digestion, absorption, and barrier. Based on the similarity of gut physiology between human and pigs, many relative studies in which piglets and porcine intestinal epithelial cells were used as the models have been done. And the results showed that using appropriate benzoic acid levels might improve gut functions via regulating enzyme activity, redox status, immunity, and microbiota, but excess administration would lead to the damage of gut health through redox status. However, the further mechanisms that some intestinal physiological functions might be regulated are not well understood. The present review will, in detail, summarize the effect of benzoic acid on gut functions.


Author(s):  
Julian P. Heath ◽  
Buford L. Nichols ◽  
László G. Kömüves

The newborn pig intestine is adapted for the rapid and efficient absorption of nutrients from colostrum. In enterocytes, colostral proteins are taken up into an apical endocytotic complex of channels that transports them to target organelles or to the basal surface for release into the circulation. The apical endocytotic complex of tubules and vesicles clearly is a major intersection in the routes taken by vesicles trafficking to and from the Golgi, lysosomes, and the apical and basolateral cell surfaces.Jejunal tissues were taken from piglets suckled for up to 6 hours and prepared for electron microscopy and immunocytochemistry as previously described.


2001 ◽  
Vol 120 (5) ◽  
pp. A504-A504
Author(s):  
A NEUMANN ◽  
M DEPKAPRONDZINSKI ◽  
C WILHELM ◽  
K FELGENHAUER ◽  
T CASPRITZ ◽  
...  

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