scholarly journals Regulated expression of the platelet-derived growth factor A chain gene in microvascular endothelial cells.

1987 ◽  
Vol 262 (30) ◽  
pp. 14381-14384 ◽  
Author(s):  
N F Starksen ◽  
G R Harsh ◽  
V C Gibbs ◽  
L T Williams
Keyword(s):  
Endothelial Cells ◽  
Growth Factor ◽  
Platelet Derived Growth Factor ◽  
Microvascular Endothelial Cells ◽  
Chain Gene ◽  
Regulated Expression ◽  
Microvascular Endothelial ◽  
A Chain

Isolation and sequencing of a cDNA clone homologous to the v-sis oncogene from human endothelial cells

1986 ◽  
Vol 6 (8) ◽  
pp. 3018-3022
Author(s):  
B D Tong ◽  
S E Levine ◽  
M Jaye ◽  
G Ricca ◽  
W Drohan ◽  
...  
Keyword(s):  
Endothelial Cells ◽  
Growth Factor ◽  
Cdna Library ◽  
Cdna Clone ◽  
Umbilical Vein ◽  
Platelet Derived Growth Factor ◽  
Human Endothelial Cells ◽  
A Chain ◽  
Umbilical Vein Endothelial Cells ◽  
Reading Frames

A clone containing the 3' end of the mRNA for the human c-sis gene (homologous to the B chain of platelet-derived growth factor) was isolated from a cDNA library derived from human umbilical vein endothelial cells and then sequenced. The analysis of possible translation products in all three reading frames indicated that the A chain of platelet-derived growth factor was not coded for within the 3' end of the c-sis mRNA. The 3' end of the mRNA for c-sis is contained in or adjacent to exon 6.

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