scholarly journals Riboflavin and rat hepatic cell structure and function. Mitochondrial oxidative metabolism in deficiency states.

1979 ◽  
Vol 254 (10) ◽  
pp. 4164-4170 ◽  
Author(s):  
C Hoppel ◽  
J P DiMarco ◽  
B Tandler
1969 ◽  
Vol 41 (2) ◽  
pp. 477-493 ◽  
Author(s):  
Bernard Tandler ◽  
Robert A. Erlandson ◽  
Archie L. Smith ◽  
Ernest L. Wynder

Mice which had been on a riboflavin-free diet for 6–8 wk were given daily intraperitoneal injections of riboflavin. The hepatic mitochondria, which in the deficient animals were greatly enlarged, were restored to normal dimensions within 3 days. Normalization of the mitochondrial population was brought about by division of the giant organelles. Dividing mitochondria were characterized by a membranous partition separating the inner compartment into two distinct chambers. Such organelles showed varying degrees of pinching at the level of the partition. The most common site of partition formation was at the base of a small mitochondrial bud. During the 1st day of recovery, dividing mitochondria were so common that they could be easily found in mitochondrial pellets. Injection of riboflavin into normally nourished mice also produced an apparent increase in the frequency of dividing mitochondria in the liver cells.


Author(s):  
Nugroho Budhiwaluyo ◽  
Rayandra Asyhar ◽  
Bambang Hariyadi

  This research aims to produce a final product in the form of a performance-assessment instrument on Cell Structure and Function experiment. The development model is ADDIE. Based on expert's judgment, the instrument was valid and can be tested in the field. Field-test results shown that the product performs high validity and reliability value on measuring student performance on Cell Structure and Function experiment. Therefore, it is concluded that this performance-assessment instrument theoretically and practically has a good quality for measuring student performance in both process and product performance on Cell Structure and Function experiment. Keywords: Development, Performance-Assessment Instrument, Cell Structure and Function Experiment 


Gene Therapy ◽  
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Adam N. Baker ◽  
Pamela S. Lagali ◽  
Stuart G. Coupland ◽  
Garfield Miller ◽  
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Author(s):  
Supriya Mahajan ◽  
Alexander Jacob ◽  
Anju Kelkar ◽  
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