Association of Type 1 Blood Group Antigens with Urinary Tract Infections in Children with Genitourinary Structural Abnormalities

1990 ◽  
Vol 144 (2 Part 2) ◽  
pp. 469-473 ◽  
Author(s):  
Joel Sheinfeld ◽  
Carlos Cordon-Cardo ◽  
William R. Fair ◽  
David D. Wartinger ◽  
Ronald Rabinowitz
Keyword(s):  
Urinary Tract ◽  
Blood Group ◽  
Urinary Tract Infections ◽  
Blood Group Antigens ◽  
Structural Abnormalities ◽  
Tract Infections

Urinary tract infections and P blood group antigens

Urology ◽  
1984 ◽  
Vol 24 (3) ◽  
pp. 232-235 ◽  
Author(s):  
S. Grant Mulholland ◽  
Michael Mooreville ◽  
C. Lowell Parsons
Keyword(s):  
Urinary Tract ◽  
Blood Group ◽  
Urinary Tract Infections ◽  
Blood Group Antigens ◽  
Tract Infections ◽  
P Blood Group

scholarly journals Sexual Dysfunction in Young Women with Type 1 Diabetes

2020 ◽  
Vol 17 (12) ◽  
pp. 4468
Author(s):  
Edyta Cichocka ◽  
Michał Jagusiewicz ◽  
Janusz Gumprecht
Keyword(s):  
Type 1 Diabetes ◽  
Urinary Tract ◽  
Sexual Function ◽  
Urinary Tract Infections ◽  
Vascular Complications ◽  
Chronic Complications ◽  
Patients With Diabetes ◽  
The Mean ◽  
Tract Infections

Introduction: Sexual dysfunctions (SD) are chronic complications that can develop due to vascular complications or autonomic neuropathy. Additionally, such complications can be of hormonal, infectious or psychogenic etiology. Objectives: The aim of study was to assess the sexual function and acceptance of the chronic disease in young sexually active women with type 1 diabetes (T1DM). Materials and methods: A total of 169 female patients with T1DM completed two standardized questionnaires, the Female Sexual Function Index (FSFI) and the Acceptance of Illness Scale (AIS). Other medical data were collected from medical history. Results: The mean FSFI score was 27.96 ± 5.00, and the mean AIS score was 29.67 ± 8.28. The score < 26 points in FSFI was obtained by 28.7% of patients. Analysis of correlation between the FSFI and the AIS showed that the higher the score on the FSFI, the higher the score on the AIS. Patients who underwent regular physical activity (55%) had a significantly higher acceptance of the disease (p = 0.0026) and reported painful intercourse significantly less frequently (p = 0.01). The value of HbA1c in the study group was 7.31 ± 1.25%. Patients with poorer glycemic control (HbA1c > 8%) obtained significantly lower scores on the FSFI (p = 0.03), whereas no differences were found on the AIS. Diabetes-related complications were observed in 25.5% of patients. The presence of chronic complications did not affect the results of the FSFI or the AIS. Patients with diabetes and hypertension had poorer functioning in the sexual sphere and had significantly lower scores on the FSFI. Past or present history of depression was reported by 36% of patients and also negatively affected acceptance of diabetes (p = 0.0015). Patients who reported recurrent urinary tract infections (17%) achieved significantly lower scores on the FSFI (p = 0.03) and showed that sex-related pain was significantly more prevalent (p = 0.02). In the case of the statement related to the embarrassment of people around the patient due to diabetes, patients with lower scores complained of SD significantly more often (p = 0.0033). Past deliveries, the type of labor, the use of contraceptives or the number of sexual partners had no influence on the overall assessment in both scales. However, in terms of desire, women who had delivered obtained higher scores (p = 0.0021). Conclusion: SD in women with T1DM may result from diabetes-related complications, hormonal disorders or recurrent genital or urinary tract infections. However, they usually have a psychological basis due to the lack of acceptance of the problems related to the treatment of diabetes.

scholarly journals Glycemic Control and Urinary Tract Infections in Women with Type 1 Diabetes: Results from the DCCT/EDIC

2016 ◽  
Vol 196 (4) ◽  
pp. 1129-1135 ◽  
Author(s):  
Sara M. Lenherr ◽  
J. Quentin Clemens ◽  
Barbara H. Braffett ◽  
Patricia A. Cleary ◽  
Rodney L. Dunn ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Urinary Tract ◽  
Glycemic Control ◽  
Urinary Tract Infections ◽  
Tract Infections

scholarly journals Type 1 Fimbriae Contribute to Catheter-Associated Urinary Tract Infections Caused by Escherichia coli

2013 ◽  
Vol 196 (5) ◽  
pp. 931-939 ◽  
Author(s):  
A. Reisner ◽  
M. Maierl ◽  
M. Jorger ◽  
R. Krause ◽  
D. Berger ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Urinary Tract ◽  
Urinary Tract Infections ◽  
Type 1 Fimbriae ◽  
Tract Infections

scholarly journals Urinary Tract Infections of Escherichia coli Strains of Chaperone-Usher System

2011 ◽  
Vol 60 (4) ◽  
pp. 279-285 ◽  
Author(s):  
BEATA M. ZALEWSKA-PIĄTEK
Keyword(s):  
Urinary Tract ◽  
Pregnant Women ◽  
Virulence Factors ◽  
Urinary Tract Infections ◽  
Bacterial Infections ◽  
Economic Problem ◽  
Etiologic Agent ◽  
E Coli ◽  
Tract Infections

Urinary tract infections are a very serious health and economic problem affecting millions of people each year worldwide. The most common etiologic agent of this type of bacterial infections, involving the upper and lower urinary tract, are E. coli strains representing approximately 80% of cases. Uropathogenic E. coli strains produce several urovirulence factors which can be divided into two main types, surface virulence factors and exported virulence factors. Surface-exposed structures include mainly extracellular adhesive organelles such as fimbriae/pili necessary in adhesion, invasion, biofilm formation and cytokine induction. Among the surface-exposed polymeric adhesive structures there are three most invasive groups, type 1 pili, type P pili and Dr family of adhesins which are bioassembled via the conserved, among Gram-negative bacteria, chaperone-usher secretion system. Type 1 and P-piliated E. coli cause cystitis and pyelonephritis. The Dr family of adhesins recognizing DAF receptor is responsible for cystitis, pyelonephritis (especially in pregnant women) and diarrhoea (in infants). In addition, Dr-positive E. coli strains carry the risk of recurrent urinary tract infections. Pyelonephritis in pregnant women leads to a series of complications such as bacteremia, urosepsis, acute respiratory distress syndrome and even death. In the era of increasing drug resistance of bacteria, the development of vaccines, drugs termed pilicides and inhibitors of adhesion may be a promising tool in the fight against urogenital infections.

scholarly journals Establishment of a Persistent Escherichia coli Reservoir during the Acute Phase of a Bladder Infection

2001 ◽  
Vol 69 (7) ◽  
pp. 4572-4579 ◽  
Author(s):  
Matthew A. Mulvey ◽  
Joel D. Schilling ◽  
Scott J. Hultgren
Keyword(s):  
Escherichia Coli ◽  
Urinary Tract ◽  
Epithelial Cells ◽  
Urinary Tract Infections ◽  
Bacterial Attachment ◽  
Bacterial Invasion ◽  
E Coli ◽  
Bladder Cells ◽  
Tract Infections

ABSTRACT The vast majority of urinary tract infections are caused by strains of uropathogenic Escherichia coli that encode filamentous adhesive organelles called type 1 pili. These structures mediate both bacterial attachment to and invasion of bladder epithelial cells. However, the mechanism by which type 1 pilus-mediated bacterial invasion contributes to the pathogenesis of a urinary tract infection is unknown. Here we show that type 1-piliated uropathogens can invade the superficial epithelial cells that line the lumenal surface of the bladder and subsequently replicate, forming massive foci of intracellular E. coli termed bacterial factories. In response to infection, superficial bladder cells exfoliate and are removed with the flow of urine. To avoid clearance by exfoliation, intracellular uropathogens can reemerge and eventually establish a persistent, quiescent bacterial reservoir within the bladder mucosa that may serve as a source for recurrent acute infections. These observations suggest that urinary tract infections are more chronic and invasive than generally assumed.

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