749: IN-1130, A Novel Transforming Growth Factor-S Type I Receptor Kinase (ALK5) Inhibitor, Regresses Fibrotic Plaque and Corrects Penile Curvature in a Rat Model of Peyronie's Disease

Peyronie’S Disease ◽

Penile Curvature ◽

Type I ◽

Receptor Kinase ◽

Peyronie's Disease ◽

Alk5 Inhibitor

EFFECT OF TRANSFORMING GROWTH FACTOR-β TYPE I RECEPTOR INHIBITOR ON THE REGRESSION OF FIBROTIC PLAQUE AND CORRECTION OF PENILE CURVATURE IN A RAT MODEL OF PEYRONIE'S DISEASE

European Urology Supplements ◽

10.1016/s1569-9056(08)60575-8 ◽

2008 ◽

Vol 7 (3) ◽

pp. 215

Author(s):

J.K. Ryu ◽

S. Piao ◽

H.Y. Shin ◽

M.J. Choi ◽

L.W. Zhang ◽

...

Keyword(s):

Growth Factor ◽

Rat Model ◽

Peyronie’S Disease ◽

Penile Curvature ◽

Type I ◽

Peyronie's Disease ◽

Receptor Inhibitor

IN-1130, a Novel Transforming Growth Factor-β Type I Receptor Kinase (Activin Receptor-like Kinase 5) Inhibitor, Promotes Regression of Fibrotic Plaque and Corrects Penile Curvature in a Rat Model of Peyronie's Disease

Journal of Sexual Medicine ◽

10.1111/j.1743-6109.2009.01216.x ◽

2009 ◽

Vol 6 (5) ◽

pp. 1284-1296 ◽

Cited By ~ 31

Author(s):

Ji-Kan Ryu ◽

Shuguang Piao ◽

Hwa-Yean Shin ◽

Min Ji Choi ◽

Lu Wei Zhang ◽

...

Keyword(s):

Growth Factor ◽

Rat Model ◽

Penile Curvature ◽

Type I ◽

Receptor Kinase ◽

Activin Receptor ◽

Receptor Like Kinase ◽

Peyronie's Disease

IN-1130, a novel transforming growth factor-β type I receptor kinase (ALK5) inhibitor, suppresses renal fibrosis in obstructive nephropathy

Kidney International ◽

10.1038/sj.ki.5001775 ◽

2006 ◽

Vol 70 (7) ◽

pp. 1234-1243 ◽

Cited By ~ 138

Author(s):

J.-A. Moon ◽

H.-T. Kim ◽

I.-S. Cho ◽

Y.Y. Sheen ◽

D.-K. Kim

Keyword(s):

Growth Factor ◽

Renal Fibrosis ◽

Obstructive Nephropathy ◽

Type I ◽

Receptor Kinase ◽

Alk5 Inhibitor

EW-7197, an oral transforming growth factor β type I receptor kinase inhibitor, for preventing peritoneal adhesion formation in a rat model

Surgery ◽

10.1016/j.surg.2018.07.005 ◽

2018 ◽

Vol 164 (5) ◽

pp. 1100-1108 ◽

Cited By ~ 4

Author(s):

Jiaywei Tsauo ◽

Ho-Young Song ◽

Eun Young Choi ◽

Dae-Kee Kim ◽

Kun Yung Kim ◽

...

Keyword(s):

Growth Factor ◽

Rat Model ◽

Kinase Inhibitor ◽

Adhesion Formation ◽

Type I ◽

Receptor Kinase ◽

Peritoneal Adhesion ◽

Peritoneal Adhesion Formation

186 TRANSFORMING GROWTH FACTOR-ß TYPE I RECEPTOR KINASE (ALK5) INHIBITOR ALLEVIATES FIBROSIS IN FIBROBLASTS DERIVED FROM HUMAN PEYRONIE'S PLAQUE

European Urology Supplements ◽

10.1016/s1569-9056(10)60190-x ◽

2010 ◽

Vol 9 (2) ◽

pp. 90-91

Author(s):

S. Piao ◽

M.J. Choi ◽

M. Tumurbaatar ◽

W.J. Kim ◽

H.R. Jin ◽

...

Keyword(s):

Growth Factor ◽

Type I ◽

Receptor Kinase ◽

Alk5 Inhibitor

Transforming Growth Factor (TGF)-β Type I Receptor Kinase (ALK5) Inhibitor Alleviates Profibrotic TGF-β1 Responses in Fibroblasts Derived from Peyronie's Plaque

Journal of Sexual Medicine ◽

10.1111/j.1743-6109.2010.01753.x ◽

2010 ◽

Vol 7 (10) ◽

pp. 3385-3395 ◽

Cited By ~ 22

Author(s):

Shuguang Piao ◽

Min Ji Choi ◽

Munkhbayar Tumurbaatar ◽

Woo Jean Kim ◽

Hai-Rong Jin ◽

...

Keyword(s):

Growth Factor ◽

Type I ◽

Receptor Kinase ◽

Alk5 Inhibitor ◽

Tgf Β1

998: Repetitive Intratunical Injection of Adenovirus Expressing Transforming Growth Factor-β1 in a Rat Induces Penile Curvature with Tunical Fibrotic Plaque: A Useful Model for the Study of Peyronie's Disease

The Journal of Urology ◽

10.1016/s0022-5347(18)33223-3 ◽

2006 ◽

Vol 175 (4S) ◽

pp. 322-322

Author(s):

Shuguang Piao ◽

Ji-Kan Ryu ◽

Hwa-Yean Shin ◽

Lu Wei Zhang ◽

Jee-Young Han ◽

...

Keyword(s):

Growth Factor ◽

Transforming Growth Factor Β1 ◽

Peyronie’S Disease ◽

Penile Curvature ◽

Peyronie's Disease

Repeated intratunical injection of adenovirus expressing transforming growth factor-β1 in a rat induces penile curvature with tunical fibrotic plaque: a useful model for the study of Peyronie’s disease

International Journal of Andrology ◽

10.1111/j.1365-2605.2007.00780.x ◽

2008 ◽

Vol 31 (3) ◽

pp. 346-353 ◽

Cited By ~ 24

Author(s):

Shuguang Piao ◽

Ji-Kan Ryu ◽

Hwa-Yean Shin ◽

Luwei Zhang ◽

Sun U. Song ◽

...

Keyword(s):

Growth Factor ◽

Transforming Growth Factor Β1 ◽

Peyronie’S Disease ◽

Penile Curvature ◽

Peyronie's Disease

EW-7197, a Transforming Growth Factor-Beta Type I Receptor Kinase Inhibitor, Ameliorates Acquired Lymphedema in a Mouse Tail Model

Lymphatic Research and Biology ◽

10.1089/lrb.2018.0070 ◽

2020 ◽

Vol 18 (5) ◽

pp. 433-438

Author(s):

Sung-Hwan Yoon ◽

Kun Yung Kim ◽

Zhe Wang ◽

Jung-Hoon Park ◽

Sang Mun Bae ◽

...

Keyword(s):

Growth Factor ◽

Transforming Growth Factor Beta ◽

Kinase Inhibitor ◽

Type I ◽

Receptor Kinase ◽

Growth Factor Beta

A Novel Small-Molecule Inhibitor of Transforming Growth Factor β Type I Receptor Kinase (SM16) Inhibits Murine Mesothelioma Tumor Growth In vivo and Prevents Tumor Recurrence after Surgical Resection

Cancer Research ◽

10.1158/0008-5472.can-06-2389 ◽

2007 ◽

Vol 67 (5) ◽

pp. 2351-2359 ◽

Cited By ~ 72

Author(s):

Eiji Suzuki ◽

Samuel Kim ◽

H.-Kam Cheung ◽

Michael J. Corbley ◽

Xiamei Zhang ◽

...

Keyword(s):

Growth Factor ◽

Tumor Growth ◽

Small Molecule ◽

Tumor Recurrence ◽

Type I ◽

Receptor Kinase ◽

Molecule Inhibitor