A prospective longitudinal study of the impact of postnatal depression on child development in a low risk sample

1996 ◽  
Vol 19 ◽  
pp. 238
Author(s):  
Lynne Murray
2011 ◽  
Vol 26 (8) ◽  
pp. 484-489 ◽  
Author(s):  
A.-L. Sutter-Dallay ◽  
L. Murray ◽  
L. Dequae-Merchadou ◽  
E. Glatigny-Dallay ◽  
M.-L. Bourgeois ◽  
...  

AbstractBackgroundFew studies of the effects of postnatal depression on child development have considered the chronicity of depressive symptoms. We investigated whether early postnatal depressive symptoms (PNDS) predicted child developmental outcome independently of later maternal depressive symptoms.MethodsIn a prospective, longitudinal study, mothers and children were followed-up from birth to 2 years; repeated measures of PNDS were made using the Edinburgh Postnatal Depression Scale (EPDS); child development was assessed using the Bayley Scales II. Multilevel modelling techniques were used to examine the association between 6 week PNDS, and child development, taking subsequent depressive symptoms into account.ResultsChildren of mothers with 6 week PNDS were significantly more likely than children of non-symptomatic mothers to have poor cognitive outcome; however, this association was reduced to trend level when adjusted for later maternal depressive symptoms.ConclusionEffects of early PNDS on infant development may be partly explained by subsequent depressive symptoms.


Author(s):  
Lynne Murray

From 1985, when I first met Channi Kumar, he played a seminal role in the research I have conducted with my colleagues on the effects of postnatal depression on child development. At the time I was a very junior researcher, struggling to get my work underway, and his enthusiasm and encouragement were invaluable. Channi played a particularly important role from 1989 when, with the support of the Tedworth Charitable Trust and the Winnicott Trust, the Winnicott Research Unit was established in Cambridge, under the joint Directorship of myself and Peter Cooper, together with Alan Stein. Channi became a key member of the Unit’s advisory committee and, right up until the time of his death, he regularly, and very kindly, provided the wisest counsel and support, and he is still very sorely missed. He was an inspiring friend and colleague, with the deepest compassion and humanity for the plight of the families he helped, and boundless enthusiasm for new perspectives and ideas that could advance understanding and clinical treatment, and I am greatly indebted to him for all his support. This chapter describes research on a prospective longitudinal study of the development of children of depressed and well mothers conducted in the Winnicott Research Unit; much of it took place under Channi’s watch. The work has involved a large number of colleagues, aside from the contributions of Peter Cooper and Alan Stein, and I am particularly grateful to Alison Hipwell, Matt Woolgar, Sheelah Seeley, Janet Edwards, Sarah Halligan, Adriane Arteche, Ian Goodyer, and Joe Herbert for their involvement and support. A diagnosis of ‘postnatal depression’ includes a wide range of possible symptoms, and therefore this unitary term can mask considerable variation in the nature of its presentation. For example, one mother could be slowed down, sleeping excessively, and barely eating, while in another, the episode may manifest itself in restlessness and agitation, with the mother being hardly able to concentrate and feeling constantly irritable. Not surprisingly, then, studies of the effects of postnatal depression on mother-infant interactions have also identified striking variability.


SLEEP ◽  
2021 ◽  
Vol 44 (Supplement_2) ◽  
pp. A203-A203
Author(s):  
Maurice Ohayon ◽  
Y J Chen ◽  
Marie-Lise Cote

Abstract Introduction Chronic nausea and vomiting (CNV), common symptoms in patients with GI disorders like gastroparesis, can be a debilitating health problem with considerable impact on patients’ health-related quality of life during daytime. Yet, little is known about how CNV may impact on sleepiness and fatigue during the daytime. Our aim was to examine the impact of CNV on daytime sleepiness and fatigue based on the data from a longitudinal study. Methods Prospective longitudinal study with two waves: 12,218 subjects interviewed by phone during wave 1 (W1); 10,931 during wave 2 (W2) three years later. The sample was representative of the US general population. Analyses included subjects participating to both waves (N=10,931). CNV was defined as episodes of nausea and vomiting occurring at least twice a month for at least 1 month (outside pregnancy). Logistic regression models were employed to determine whether CNV is a predictive variable for excessive sleepiness or fatigue. Results Out of all W1 participants, 9.8% (95% CI: 9.2%-10.4%) reported nausea only while 3% (95% CI: 2.7%-3.3%) reported CNV. In W2, 7.7% (95% CI: 7.2%-8.2%) reported nausea only and 2.5% (95% CI: 2.2%-2.8%) reported having CNV. Of the subjects who participated in both W1 and W2, 25.7% of them reported CNV in W1. CNV subjects reported more frequently excessive daytime sleepiness (53.5% vs. 25.9%) and being moderately or severely fatigued (38.6% vs, 5.4%) compared with the participants without nausea or vomiting. After controlling for age, sex, BMI, health status, alcohol intake, sleep disorders and psychiatric disorders that might impact on daytime sleepiness or fatigue, it was found that subjects with CNV at both W1 and W2 had a significantly higher relative risk of reporting daytime sleepiness (RR: 2.7 (95% CI:1.9–3.9) p<0.0001) and fatigue (RR: 4.9 (95% CI:3.2–7.5) p<0.0001) at W2, compared with the participants without nausea or vomiting. Conclusion Many factors are likely to influence daytime sleepiness. CNV appears to be an important contributor even after controlling for several factors that can explain the sleepiness. This underlines the extent to which alertness could be disturbed and impacted by chronicity of nausea/vomiting symptoms. Support (if any) This analysis study was funded by Takeda Pharmaceutical Company


2014 ◽  
Vol 57 (3) ◽  
pp. 1108-1126 ◽  
Author(s):  
Ruth M. Reeder ◽  
Jill B. Firszt ◽  
Laura K. Holden ◽  
Michael J. Strube

PurposeThe purpose of this study was to examine the rate of progress in the 2nd implanted ear as it relates to the 1st implanted ear and to bilateral performance in adult sequential cochlear implant recipients. In addition, this study aimed to identify factors that contribute to patient outcomes.MethodThe authors performed a prospective longitudinal study in 21 adults who received bilateral sequential cochlear implants. Testing occurred at 6 intervals: prebilateral through 12 months postbilateral implantation. Measures evaluated speech recognition in quiet and noise, localization, and perceived benefit.ResultsSecond ear performance was similar to 1st ear performance by 6 months postbilateral implantation. Bilateral performance was generally superior to either ear alone; however, participants with shorter 2nd ear length of deafness (<20 years) had more rapid early improvement and better overall outcomes than those with longer 2nd ear length of deafness (>30 years). All participants reported bilateral benefit.ConclusionsAdult cochlear implant recipients demonstrated benefit from 2nd ear implantation for speech recognition, localization, and perceived communication function. Because performance outcomes were related to length of deafness, shorter time between surgeries may be warranted to reduce negative length-of-deafness effects. Future study may clarify the impact of other variables, such as preimplant hearing aid use, particularly for individuals with longer periods of deafness.


2016 ◽  
Vol 45 (1) ◽  
pp. 59-65 ◽  
Author(s):  
Golnosh Bahrami ◽  
Michael Vaeth ◽  
Lise-Lotte Kirkevang ◽  
Ann Wenzel ◽  
Flemming Isidor

Mastology ◽  
2018 ◽  
Vol 28 (s1) ◽  
pp. 29-29
Author(s):  
Marceila A. Fuzissaki ◽  
◽  
Carlos E. Paiva ◽  
Marco A. Oliveira ◽  
Mariana T. M. Lima ◽  
...  

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