Higher in-hospital and post-discharge mortality and hospital charges in cirrhotic patients with acute respiratory illness in the United States

2018 ◽  
Vol 68 ◽  
pp. S704-S705
Author(s):  
B. Zou ◽  
Y.H. Yeo ◽  
D. Jeong ◽  
E. Sheen ◽  
H. Park ◽  
...  
Keyword(s):  
United States ◽  
Respiratory Illness ◽  
The United States ◽  
Hospital Charges ◽  
Acute Respiratory Illness ◽  
Post Discharge ◽  
Cirrhotic Patients

scholarly journals Outbreaks of Adenovirus-associated Respiratory Illness on 5 College Campuses in the United States, 2018–2019

2020 ◽  
Author(s):  
Stephanie A Kujawski ◽  
Xiaoyan Lu ◽  
Eileen Schneider ◽  
David Blythe ◽  
Sameh Boktor ◽  
...  
Keyword(s):  
United States ◽  
Social History ◽  
Military Training ◽  
Respiratory Illness ◽  
The United States ◽  
College Campuses ◽  
Whole Genome Sequence ◽  
Whole Genome ◽  
Acute Respiratory Illness ◽  
Symptom Presentation

Abstract Background Human adenoviruses (HAdVs) are commonly associated with acute respiratory illness. HAdV outbreaks are well documented in congregate military training settings, but less is known about outbreaks on college campuses. During fall 2018 and spring 2019, 5 United States (US) colleges reported increases in HAdV-associated respiratory illness. Investigations were performed to better understand HAdV epidemiology in this setting. Methods A case was defined as a student at one of the 5 colleges, with acute respiratory illness and laboratory-confirmed HAdV infection during October 2018–December 2018 or March–May 2019. Available respiratory specimens were typed by HAdV type-specific real-time polymerase chain reaction assays, and for a subset, whole genome sequencing was performed. We reviewed available medical records and cases were invited to complete a questionnaire, which included questions on symptom presentation, social history, and absenteeism. Results We identified 168 HAdV cases. Median age was 19 (range, 17–22) years and 102 cases (61%) were male. Eleven cases were hospitalized, 10 with pneumonia; 2 cases died. Among questionnaire respondents, 80% (75/94) missed ≥ 1 day of class because of their illness. Among those with a type identified (79%), HAdV types 4 and 7 were equally detected, with frequency of each varying by site. Genome types 4a1 and 7d were identified, respectively, by whole genome sequence analysis. Conclusions HAdV respiratory illness was associated with substantial morbidity and missed class time among young, generally healthy adults on 5 US college campuses. HAdVs should be considered a cause of respiratory illness outbreaks in congregate settings such as college campuses.

scholarly journals Influenza vaccine effectiveness against hospitalization in the United States, 2019-2020

2020 ◽  
Author(s):  
Mark W Tenforde ◽  
H Keipp Talbot ◽  
Christopher H Trabue ◽  
Manjusha Gaglani ◽  
Tresa M McNeal ◽  
...  
Keyword(s):  
United States ◽  
Influenza Vaccine ◽  
Influenza Vaccination ◽  
Respiratory Illness ◽  
The United States ◽  
Vaccine Effectiveness ◽  
Influenza Viruses ◽  
Current Season ◽  
Hospital Resources ◽  
Negative Controls

Abstract Background Influenza causes significant morbidity and mortality and stresses hospital resources during periods of increased circulation. We evaluated the effectiveness of the 2019-2020 influenza vaccine against influenza-associated hospitalizations in the United States. Methods We included adults hospitalized with acute respiratory illness at 14 hospitals and tested for influenza viruses by reserve transcription polymerase chain reaction. Vaccine effectiveness (VE) was estimated by comparing the odds of current-season influenza vaccination in test-positive influenza cases versus test-negative controls, adjusting for confounders. VE was stratified by age and major circulating influenza types along with A(H1N1)pdm09 genetic subgroups. Results 3116 participants were included, including 18% (553) influenza-positive cases. Median age was 63 years. Sixty-seven percent (2079) received vaccination. Overall adjusted VE against influenza viruses was 41% (95% confidence interval [CI]: 27-52). VE against A(H1N1)pdm09 viruses was 40% (95% CI: 24-53) and 33% against B viruses (95% CI: 0-56). Of the two major A(H1N1)pdm09 subgroups (representing 90% of sequenced H1N1 viruses), VE against one group (5A+187A,189E) was 59% (95% CI: 34-75) whereas no significant VE was observed against the other group (5A+156K) [-1%, 95% CI: -61-37]. Conclusions In a primarily older population, influenza vaccination was associated with a 41% reduction in risk of hospitalized influenza illness.

Impact of smoking on respiratory illness—related outpatient visits among 50- to 75-year-olds in the United States

2002 ◽  
Vol 24 (2) ◽  
pp. 317-324 ◽  
Author(s):  
Lynn H. Hoffman ◽  
David R. Strutton ◽  
Paul E. Stang ◽  
Susan L. Hogue
Keyword(s):  
United States ◽  
Respiratory Illness ◽  
The United States ◽  
Outpatient Visits

BURDEN OF MORTALITY AND DISEASE ATTRIBUTABLE TO HOSPITALIZED ATRIAL FIBRILLATION IN CIRRHOTIC PATIENTS IN THE UNITED STATES: A NATIONWIDE, PROPENSITY SCORE MATCHED ANALYSIS

2019 ◽  
Vol 73 (9) ◽  
pp. 359
Author(s):  
Tarun Jacob Bathini ◽  
Wisit Cheungpasitporn ◽  
Charat Thongprayoon ◽  
Ronpichai Chokesuwattanaskul ◽  
Patompong Ungprasert ◽  
...  
Keyword(s):  
United States ◽  
Atrial Fibrillation ◽  
Propensity Score ◽  
The United States ◽  
Cirrhotic Patients

scholarly journals Enterovirus D68–Associated Acute Respiratory Illness — New Vaccine Surveillance Network, United States, July–October, 2017 and 2018

2019 ◽  
Vol 68 (12) ◽  
pp. 277-280 ◽  
Author(s):  
Stephanie A. Kujawski ◽  
Claire M. Midgley ◽  
Brian Rha ◽  
Joana Y. Lively ◽  
W. Allan Nix ◽  
...  
Keyword(s):  
United States ◽  
Respiratory Illness ◽  
Acute Respiratory Illness ◽  
Surveillance Network ◽  
Enterovirus D68 ◽  
Vaccine Surveillance

TIME-MOTION STUDY OF PRACTICING PEDIATRICIANS

PEDIATRICS ◽  
1966 ◽  
Vol 38 (2) ◽  
pp. 254-263 ◽  
Author(s):  
Abraham B. Bergman ◽  
Steven W. Dassel ◽  
Ralph J. Wedgwood
Keyword(s):  
United States ◽  
Health Care ◽  
Child Health ◽  
Decisive Role ◽  
Respiratory Illness ◽  
The United States ◽  
Child Health Care ◽  
Time Motion ◽  
Motion Study ◽  
Paper Work

Four practicing pediatricians were followed by an observer with a stopwatch for a total of 18 days to gain a profile of how their working days were spent. An average of 48% of the day was spent with patients, 12.5% on the phone, and 9% on paper work. Fifty per cent of patient time was spent with well children, and 22% on children with minor respiratory illness. Intellectual understimulation seemed to arise from spending the majority of time with children who did not require their special talents. In view of the alarming decline in ratio of physicians to child population, pediatricians are urged to play a decisive role in formulating the alternative patterns of child health care that must inevitably develop in the United States.

Abstract 45: Thrombolytic Treatment for In-Hospital Ischemic Strokes in United States

Stroke ◽  
2013 ◽  
Vol 44 (suppl_1) ◽  
Author(s):  
Tenbit Emiru ◽  
Malik M Adil ◽  
Adnan I Qureshi
Keyword(s):  
United States ◽  
Ischemic Stroke ◽  
Length Of Stay ◽  
Hospital Mortality ◽  
Acute Ischemic Stroke ◽  
Clinical Characteristics ◽  
The United States ◽  
Treated Group ◽  
Hospital Charges ◽  
Thrombolytic Treatment

BACKGROUND: Despite the recent emphasis on protocols for emergent triage and treatment of in-hospital acute ischemic stroke, there is little data on rates and outcomes of patients receiving thrombolytics for in-hospital ischemic strokes. OBJECTIVE: To determine the rates of in-hospital ischemic stroke treated with thrombolytics and to compare outcomes with patients treated with thrombolytics on admission. DESIGN/METHODS: We analyzed a seven-year data (2002-2009) from the National Inpatient Survey (NIS), a nationally representative inpatient database in the United States. We identified patients who had in-hospital ischemic strokes (defined by thrombolytic treatment after one day of hospitalization) and those who received thrombolytics on the admission day. We compared demographics, baseline clinical characteristics, in hospital complications, length of stay, hospitalization charges, and discharge disposition, between the two patient groups. RESULT: A total of 18036 (21.5%) and 65912 (78.5%) patients received thrombolytics for in-hospital and on admission acute ischemic stroke, respectively. In hospital complications such as pneumonia (5.0% vs. 3.4%, p=0.0006), deep venous thrombosis (1.9% vs. 0.6%, p<0.0001) and pulmonary embolism (0.8% vs. 0.4%, p=0.01) were significantly higher in the in-hospital group compared to on admission thrombolytic treated group. Hospital length of stay and mean hospital charges were not different between the two groups. Patients who had in-hospital strokes had had higher rates of in hospital mortality (12.1% vs. 10.6%, p=0.02). In a multivariate analysis, in-hospital thrombolytic treated group had higher in-hospital mortality after adjustment for age, gender and baseline clinical characteristics (odds ratio 0.84, 95% confidence interval 0.74-0.95, p=0.008). CONCLUSION/RELEVANCE: In current practice, one out of every five acute ischemic stroke patients treated with thrombolytics is receiving treatment for in-hospital strokes. The higher mortality and complicated hospitalization in such patients needs to be recognized.

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