Presenting conditions of 1539 population-based lung cancer patients by cell type and stage in New Hampshire and Vermont

Abstract Introduction Among malignant diseases, lung carcinoma is the most common cancer in men worldwide in terms of both incidence and mortality. Its increasing incidence in developing countries like India is an important public health problem. This work aimed to study the demographic, clinical, radiological, and histological features of patients with confirmed lung cancer. Materials and Methods A total of 50 patients with histologically confirmed lung cancer at a tertiary care center in India from August 2016 to September 2018 were studied and analyzed. Results Out of 50 diagnosed lung cancer patients, 86% were men and 14% women; 31 (62%) patients were aged more than 60 years. Majority were smokers (84%) and all were men. Cough (94%) was the most common presenting symptom followed by dyspnea (68%), chest pain (48%), and hemoptysis (38%). Of the 50 patients, 29 (58%) had soft tissue density mass lesion on radiograph. Squamous cell carcinoma (SCC) was the diagnosed histological cell type in 24 (48%) patients and adenocarcinoma in 21 (42%) patients. Distant metastasis was observed in 20 (40%) patients. Conclusion In this study, the most common histopathological cell type is SCC. Patients aged more than 50 years and smokers are at high risk of lung cancer. Patients with a smoking history and persistent respiratory symptoms should be promptly evaluated for lung malignancy.

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Population-based differences in the outcome and presentation of lung cancer patients based upon racial, histologic, and economic factors in all lung patients and those with metastatic disease

Cancer Medicine ◽

10.1002/cam4.1430 ◽

2018 ◽

Vol 7 (4) ◽

pp. 1211-1220 ◽

Cited By ~ 9

Author(s):

John Michael Varlotto ◽

Richard Voland ◽

Kerrie McKie ◽

John C. Flickinger ◽

Malcolm M. DeCamp ◽

...

Keyword(s):

Lung Cancer ◽

Cancer Patients ◽

Metastatic Disease ◽

Population Based ◽

Economic Factors ◽

Lung Cancer Patients

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Comorbidity and survival of Danish lung cancer patients from 2000–2011: a population-based cohort study

Clinical Epidemiology ◽

10.2147/clep.s47473 ◽

2013 ◽

pp. 31 ◽

Cited By ~ 21

Author(s):

Thomas Deleuran ◽

Mette Sogaard ◽

Mette Nørgaard ◽

Reimar W. Thomsen ◽

Jacobsen ◽

...

Keyword(s):

Lung Cancer ◽

Cohort Study ◽

Cancer Patients ◽

Population Based ◽

Lung Cancer Patients

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A New Multiparametric Classification in Lung Cancer Patients - S.M.I.G.

Tumori Journal ◽

10.1177/030089168306900511 ◽

1983 ◽

Vol 69 (5) ◽

pp. 437-443 ◽

Cited By ~ 2

Author(s):

Claudio Modini ◽

Mario Albertucci ◽

Franco Cicconetti ◽

Donatella Tirindelli Danesi ◽

Renzo Cristiani ◽

...

Keyword(s):

Lung Cancer ◽

Growth Rate ◽

Mortality Rate ◽

Cancer Patients ◽

Cell Type ◽

Tnm System ◽

Lung Cancer Patients ◽

The Difference

The classification of bronchogenic carcinoma as a function of the prognosis is still an open field. The evaluation of stage, by use of the TNM system, and histologic cell type is not sufficient to guarantee a correct prognosis. The growth rate of the neoplasm is another important parameter. We propose a classification that takes into account the stage (S), histologic cell type (M), immune status (I) and the growth rate of the primary tumor (G): S.M.I.G. We studied 90 lung cancer patients according to the S.M.I.G. classification and we observed that their prognoses were directly correlated with their S.M.I.G. scores (the higher the score, the higher the 10-month mortality rate). The mortality rates within the first 10 months of follow-up were respectively 0%, 0%, 36.36%, 68%, 90.9% for the 5 groups obtained by S.M.I.G. The difference is statistically significant (P < 0.0075) and there is a linear correlation between the mortality rate and the score assigned to each group (R = 0.943; P < 0.05). The S.M.I.G. classification can predict the prognosis more efficiently than the usual classification (TNM) and histological cell type.

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