597 Apolipoprotein E ε4 allele as a risk gene for early changes in temporal lobe structures — MRI volumetric and cognitive changes

1996 ◽  
Vol 17 (4) ◽  
pp. S148-S149
Author(s):  
I.I. Alafuzoff ◽  
P.J. Riekkinen ◽  
H.S. Soininen
Keyword(s):  
Apolipoprotein E ◽  
Temporal Lobe ◽  
Cognitive Changes ◽  
Risk Gene ◽  
Ε4 Allele

The apolipoprotein E ε4 allele is not associated with early onset temporal lobe epilepsy

Neuroreport ◽  
1997 ◽  
Vol 8 (5) ◽  
pp. 1235-1237 ◽  
Author(s):  
Ingmar Blümcke ◽  
Anke Brockhaus ◽  
Christian Scheiwe ◽  
Britta Rollbrocker ◽  
Helmut K. Wolf ◽  
...  
Keyword(s):  
Temporal Lobe Epilepsy ◽  
Apolipoprotein E ◽  
Temporal Lobe ◽  
Early Onset ◽  
Ε4 Allele

scholarly journals Apolipoprotein E ε4 Allele Is Unrelated to Cognitive or Functional Decline in Alzheimer’s Disease: Retrospective and Prospective Analysis

2006 ◽  
Vol 22 (1) ◽  
pp. 73-82 ◽  
Author(s):  
Timothy Kleiman ◽  
Kristina Zdanys ◽  
Benjamin Black ◽  
Tracy Rightmer ◽  
Monique Grey ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Apolipoprotein E ◽  
Functional Decline ◽  
Prospective Analysis ◽  
Ε4 Allele

Lack of Association of Apolipoprotein E ε4 Allele Dose with Cerebral Glucose Metabolism in Alzheimer Disease

1998 ◽  
Vol 12 (4) ◽  
pp. 362-367 ◽  
Author(s):  
Nobutsugu Hirono ◽  
Etsuro Mori ◽  
Minoru Yasuda ◽  
Kazunari Ishii ◽  
Yoshitaka Ikejiri ◽  
...  
Keyword(s):  
Glucose Metabolism ◽  
Alzheimer Disease ◽  
Apolipoprotein E ◽  
Cerebral Glucose Metabolism ◽  
Ε4 Allele

Apolipoprotein E ε4 allele is associated with deposition of amyloid β-protein following head injury

1995 ◽  
Vol 1 (2) ◽  
pp. 135-137 ◽  
Author(s):  
James A.R. Nicoll ◽  
Gareth W. Roberts ◽  
David I. Graham
Keyword(s):  
Head Injury ◽  
Apolipoprotein E ◽  
Amyloid Β ◽  
Amyloid Β Protein ◽  
Β Protein ◽  
Ε4 Allele

scholarly journals Postmenopausal cognitive changes and androgen levels in the context of apolipoprotein E polymorphism

2017 ◽  
Vol 5 ◽  
pp. 1148-1159 ◽  
Author(s):  
Iwona Bojar ◽  
Jarosław Pinkas ◽  
Mariusz Gujski ◽  
Alfred Owoc ◽  
Dorota Raczkiewicz ◽  
...  
Keyword(s):  
Apolipoprotein E ◽  
Cognitive Changes ◽  
Apolipoprotein E Polymorphism ◽  
Androgen Levels

Apolipoprotein E ε4 allele frequency in elderly depressed patients with and without cerebrovascular disease

2007 ◽  
Vol 257 (1-2) ◽  
pp. 280-283 ◽  
Author(s):  
Latchezar Traykov ◽  
Anne Catherine Bayle ◽  
Florence Latour ◽  
Hermine Lenoir ◽  
Marie-Laure Seux ◽  
...  
Keyword(s):  
Cerebrovascular Disease ◽  
Apolipoprotein E ◽  
Allele Frequency ◽  
Depressed Patients ◽  
Ε4 Allele

Differences Between APOE Carriers and Non-APOE Carriers on Neurocognitive Tests: Jensen Effects?

2018 ◽  
Vol 33 (6) ◽  
pp. 353-361 ◽  
Author(s):  
Jan te Nijenhuis ◽  
Kyu Yeong Choi ◽  
Yu Yong Choi ◽  
Jang Jae Lee ◽  
Eun Hyun Seo ◽  
...  
Keyword(s):  
Older Adults ◽  
At Risk ◽  
Risk Factor ◽  
Apolipoprotein E ◽  
Test Scores ◽  
General Intelligence ◽  
Apoe Ε4 ◽  
Neurocognitive Tests ◽  
Ε4 Allele ◽  
The Difference

Background: Being a carrier of the apolipoprotein E (APOE) ε4 allele is a clear risk factor for development of Alzheimer’s disease (AD). On some neurocognitive tests, there are smaller differences between carriers and noncarriers, while other tests show larger differences. Aims: We explore whether the size of the difference between carriers and noncarriers is a function of how well the tests measure general intelligence, so whether there are Jensen effects. Methods: We used the method of correlated vectors on 441 Korean older adults at risk for AD and 44 with AD. Results: Correlations between APOE carriership and test scores ranged from −.05 to .11 (normal), and −.23 to .54 (AD). The differences between carriers and noncarriers were Jensen effects: r = .31 and r = .54, respectively. Conclusion: A composite neurocognitive score may show a clearer contrast between APOE carriers and noncarriers than a large number of scores of single neurocognitive tests.

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