Differential regulation of tyrosine hydroxylase and estradiol receptor expression in the rainbow trout brain

2003 ◽  
Vol 199 (1-2) ◽  
pp. 37-47 ◽  
Author(s):  
A Vetillard ◽  
C Atteke ◽  
C Saligaut ◽  
P Jego ◽  
T Bailhache
2021 ◽  
Vol 22 (12) ◽  
pp. 6478
Author(s):  
Lian Hollander-Cohen ◽  
Matan Golan ◽  
Berta Levavi-Sivan

From mammals to fish, reproduction is driven by luteinizing hormone (LH) and follicle-stimulating hormone (FSH) temporally secreted from the pituitary gland. Teleost fish are an excellent model for addressing the unique regulation and function of each gonadotropin cell since, unlike mammals, they synthesize and secrete LH and FSH from distinct cells. Only very distant vertebrate classes (such as fish and birds) demonstrate the mono-hormonal strategy, suggesting a potential convergent evolution. Cell-specific transcriptome analysis of double-labeled transgenic tilapia expressing GFP and RFP in LH or FSH cells, respectively, yielded genes specifically enriched in each cell type, revealing differences in hormone regulation, receptor expression, cell signaling, and electrical properties. Each cell type expresses a unique GPCR signature that reveals the direct regulation of metabolic and homeostatic hormones. Comparing these novel transcriptomes to that of rat gonadotrophs revealed conserved genes that might specifically contribute to each gonadotropin activity in mammals, suggesting conserved mechanisms controlling the differential regulation of gonadotropins in vertebrates.


2002 ◽  
Vol 103 (1-2) ◽  
pp. 116-129 ◽  
Author(s):  
Mayka Tomás-Camardiel ◽  
Antonio J Herrera ◽  
José L Venero ◽  
Mari Cruz Sánchez-Hidalgo ◽  
Josefina Cano ◽  
...  

2011 ◽  
Vol 40 (5) ◽  
pp. 498-522 ◽  
Author(s):  
Nazira El-Hage ◽  
Elizabeth M. Podhaizer ◽  
Jamie Sturgill ◽  
Kurt F. Hauser

2002 ◽  
Vol 449 (4) ◽  
pp. 374-389 ◽  
Author(s):  
Angelique Vetillard ◽  
Sanae Benanni ◽  
Christian Saligaut ◽  
Patrick Jego ◽  
Thierry Bailhache

Toxicology ◽  
2011 ◽  
Vol 287 (1-3) ◽  
pp. 21-28 ◽  
Author(s):  
Jiali Cai ◽  
Chonggang Wang ◽  
Tian Wu ◽  
João Manuel Lopes Moreno ◽  
Yuanfu Zhong ◽  
...  

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