Coordinate Induction of Tetrahydrobiopterin Synthesis and Nitric Oxide Synthase Activity in Chicken Macrophages: Upregulation of GTP-Cyclohydrolase I Activity

Hydrogen peroxide stimulates tetrahydrobiopterin synthesis through the induction of GTP-cyclohydrolase I and increases nitric oxide synthase activity in vascular endothelial cells

Free Radical Biology and Medicine ◽

10.1016/s0891-5849(03)00172-2 ◽

2003 ◽

Vol 34 (10) ◽

pp. 1343-1352 ◽

Cited By ~ 49

Author(s):

Shunichi Shimizu ◽

Kazuhiro Shiota ◽

Shinichiro Yamamoto ◽

Yoshiyuki Miyasaka ◽

Masakazu Ishii ◽

...

Keyword(s):

Nitric Oxide ◽

Hydrogen Peroxide ◽

Endothelial Cells ◽

Nitric Oxide Synthase ◽

Vascular Endothelial Cells ◽

Vascular Endothelial ◽

Gtp Cyclohydrolase I ◽

Gtp Cyclohydrolase ◽

Oxide Synthase ◽

Apolipoprotein A-I mimetic peptide inhibits atherosclerosis by increasing the tetrahydrobiopterin through regulating GTP-cyclohydrolase 1 and reducing uncoupled endothelial nitric oxide synthase activity

Atherosclerosis ◽

10.1016/j.atherosclerosis.2021.05.019 ◽

2021 ◽

Author(s):

Da-Sheng Ning ◽

Jian Ma ◽

Yue-Ming Peng ◽

Yan Li ◽

Ya-Ting Chen ◽

...

Keyword(s):

Nitric Oxide ◽

Nitric Oxide Synthase ◽

Endothelial Nitric Oxide Synthase ◽

Gtp Cyclohydrolase ◽

Mimetic Peptide ◽

Apolipoprotein A ◽

Oxide Synthase ◽

Endothelial Nitric Oxide ◽

Expressions of GTP-cyclohydrolase I (GTP-CH I) and inducible nitric oxide synthase (iNOS) mRNAs in MC3T3-E1 cells activated by cytokines

The Japanese Journal of Pharmacology ◽

10.1016/s0021-5198(19)40900-1 ◽

1998 ◽

Vol 76 ◽

pp. 198

Author(s):

Akifumi Togari ◽

Michitsugu Arai ◽

Makio Mogi ◽

Ayami Kondo

Keyword(s):

Nitric Oxide ◽

Nitric Oxide Synthase ◽

Gtp Cyclohydrolase I ◽

Gtp Cyclohydrolase ◽

Oxide Synthase ◽

Endothelin-1 Inhibits Induction of Nitric Oxide Synthase and GTP Cyclohydrolase I in Rat Mesangial Cells

Pharmacology ◽

10.1159/000139436 ◽

1996 ◽

Vol 53 (4) ◽

pp. 241-249 ◽

Cited By ~ 22

Author(s):

Junichi Hirahashi ◽

Toshio Nakaki ◽

Keiichi Hishikawa ◽

Takeshi Marumo ◽

Toshio Yasumori ◽

...

Keyword(s):

Nitric Oxide ◽

Nitric Oxide Synthase ◽

Mesangial Cells ◽

Gtp Cyclohydrolase I ◽

Gtp Cyclohydrolase ◽

Endothelin 1 ◽

Oxide Synthase

Garlic can induce both GTP cyclohydrolase and nitric oxide synthase activity in choriocarcinoma cells

Biochemical Society Transactions ◽

10.1042/bst023543s ◽

1995 ◽

Vol 23 (4) ◽

pp. 543S-543S ◽

Cited By ~ 8

Author(s):

SUREN R. SOORANNA ◽

JAYSHREE HIRANI ◽

INDRAJIT DAS

Keyword(s):

Nitric Oxide ◽

Nitric Oxide Synthase ◽

Gtp Cyclohydrolase ◽

Choriocarcinoma Cells ◽

Oxide Synthase ◽

Suppressed expression of GTP cyclohydrolase I mRNA and accelerated expression of inducible nitric oxide synthase mRNA in endomyocardial biopsy specimens from patients with dilated cardiomyopathy

Clinica Chimica Acta ◽

10.1016/j.cccn.2004.10.004 ◽

2005 ◽

Vol 353 (1-2) ◽

pp. 103-107 ◽

Cited By ~ 4

Author(s):

Masatsugu Ohtsuki ◽

Takahide Nomura ◽

Shin-ichiro Morimoto ◽

Shinya Hiramitsu ◽

Akihisa Uemura ◽

...

Keyword(s):

Nitric Oxide ◽

Nitric Oxide Synthase ◽

Dilated Cardiomyopathy ◽

Endomyocardial Biopsy ◽

Gtp Cyclohydrolase I ◽

Gtp Cyclohydrolase ◽

Biopsy Specimens ◽

Oxide Synthase ◽

GTP cyclohydrolase I gene transfer augments intracellular tetrahydrobiopterin in human endothelial cells: effects on nitric oxide synthase activity, protein levels and dimerisation

Cardiovascular Research ◽

10.1016/s0008-6363(02)00460-1 ◽

2002 ◽

Vol 55 (4) ◽

pp. 838-849 ◽

Cited By ~ 81

Author(s):

S Cai

Keyword(s):

Nitric Oxide ◽

Endothelial Cells ◽

Nitric Oxide Synthase ◽

Gene Transfer ◽

Gtp Cyclohydrolase I ◽

Human Endothelial Cells ◽

Protein Levels ◽

Oxide Synthase ◽

Nitric Oxide Synthase Activity ◽

I Gene

Induction of Inducible Nitric Oxide Synthase and its Corresponding Tetrahydrobiopterin-Cofactor-Synthesizing Enzyme GTP-Cyclohydrolase I During Cutaneous Wound Repair

Journal of Investigative Dermatology ◽

10.1046/j.1523-1747.1998.00434.x ◽

1998 ◽

Vol 111 (6) ◽

pp. 1058-1064 ◽

Cited By ~ 86

Author(s):

Stefan Frank ◽

Josef Pfeilschifter ◽

Marianne Madlener ◽

Sabine Werner

Keyword(s):

Nitric Oxide ◽

Nitric Oxide Synthase ◽

Wound Repair ◽

Gtp Cyclohydrolase I ◽

Gtp Cyclohydrolase ◽

Cutaneous Wound ◽

Oxide Synthase ◽

Coexpression of GTP cyclohydrolase I and inducible nitric oxide synthase mRNAs in mouse osteoblastic cells activated by proinflammatory cytokines

FEBS Letters ◽

10.1016/s0014-5793(98)00531-6 ◽

1998 ◽

Vol 428 (3) ◽

pp. 212-216 ◽

Cited By ~ 31

Author(s):

Akifumi Togari ◽

Michitsugu Arai ◽

Makio Mogi ◽

Ayami Kondo ◽

Toshiharu Nagatsu

Keyword(s):

Nitric Oxide ◽

Nitric Oxide Synthase ◽

Proinflammatory Cytokines ◽

Osteoblastic Cells ◽

Gtp Cyclohydrolase I ◽

Gtp Cyclohydrolase ◽

Oxide Synthase ◽

GTP Cyclohydrolase I mRNA Is Induced by LPS in Vascular Smooth Muscle: Characterization, Sequence and Relationship to Nitric Oxide Synthase

Biochemical and Biophysical Research Communications ◽

10.1006/bbrc.1993.2062 ◽

1993 ◽

Vol 195 (1) ◽

pp. 435-441 ◽

Cited By ~ 79

Author(s):

Y. Hattori ◽

S.S. Gross

Keyword(s):

Nitric Oxide ◽

Smooth Muscle ◽

Nitric Oxide Synthase ◽

Vascular Smooth Muscle ◽

Gtp Cyclohydrolase I ◽

Gtp Cyclohydrolase ◽

Oxide Synthase