Effect of fractionated regional external beam radiotherapy on peripheral blood cell count

2001 ◽  
Vol 50 (2) ◽  
pp. 465-472 ◽  
Author(s):  
B Zachariah ◽  
S.S Jacob ◽  
C Gwede ◽  
A Cantor ◽  
J Patil ◽  
...  
Keyword(s):  
Blood Cell ◽  
Cell Count ◽  
Peripheral Blood ◽  
External Beam Radiotherapy ◽  
Peripheral Blood Cell ◽  
External Beam ◽  
Blood Cell Count

scholarly journals Changes in the peripheral blood cell count in pediatric patients with Down syndrome

2019 ◽  
Vol 47 (8) ◽  
pp. 3757-3762
Author(s):  
Niculina Mang ◽  
Anda C. Vizitiu ◽  
Andrei Anghel
Keyword(s):  
Down Syndrome ◽  
Blood Cell ◽  
Cell Count ◽  
Peripheral Blood ◽  
Thyroid Dysfunction ◽  
Blood Count ◽  
Pediatric Patients ◽  
Complete Blood Count ◽  
Peripheral Blood Cell ◽  
Blood Cell Count

Objectives Down syndrome (DS) is associated with multiple complications, including a high risk of leukemia and thyroid dysfunction. This clinical study aimed to examine the complete blood cell count in patients with DS without leukemia or transient abnormal myelopoiesis. We also aimed to evaluate the effect of thyroid dysfunction on hematological anomalies in DS. Methods We analyzed the peripheral blood cell count in 23 pediatric patients with DS with and without thyroid dysfunction and in 17 pediatric patients without DS with thyroid dysfunction. Results Patients with DS showed greater neutrophilia and lymphopenia than did patients with DS and hypothyroidism and patients with hypothyroidism. Surprisingly, patients with DS showed a significant degree of eosinopenia in the peripheral blood. Interestingly, hypothyroidism had an attenuating effect on different lineages in the complete blood count. However, these anomalies were specific for DS. Conclusions Our clinical findings support previous data on DS-associated changes in the complete blood count. Our study also shows novel alterations in the complete blood count in leukemia-free patients with DS in association with hypothyroidism. The attenuating effect of thyroid dysfunction on changes in different lineages in the context of DS is novel and deserves further analysis in larger studies.

Systemic immune response and peripheral blood cell count in patients with a history of breast cancer

Pteridines ◽  
2013 ◽  
Vol 24 (3) ◽  
pp. 211-217 ◽  
Author(s):  
Vlastislav Šrámek ◽  
Bohuslav Melichar ◽  
Hana Študentová ◽  
Hana Kalábová ◽  
David Vrána ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Blood Cell ◽  
Cell Count ◽  
Peripheral Blood ◽  
Peripheral Blood Cell ◽  
Breast Cancer Patients ◽  
Blood Cell Count ◽  
Serum Neopterin ◽  
History Of ◽  
Urinary Neopterin

AbstractThe aim of the present study was to evaluate the association between changes in peripheral blood cell count and neopterin concentrations in patients with a history of breast cancer. Peripheral blood cell count, serum ferritin, serum neopterin and urinary neopterin concentrations were determined in 61 patients with a history of breast cancer and 74 control subjects. Hemoglobin, relative lymphocyte count and absolute lymphocyte count were lower, and relative neutrophil count, ferritin and serum neopterin concentrations were significantly higher in breast cancer patients than in controls. Compared to controls, the difference in hemoglobin concentration was statistically significant only in patients with active disease. Significant negative correlations were observed between urinary neopterin and hemoglobin as well as between serum neopterin and relative lymphocyte counts in breast cancer patients. Increased ferritin concentrations were associated with a history of hypertension, but higher absolute lymphocyte counts were associated with hypertension only in subjects without history of cancer. In conclusion, in patients with a history of breast cancer, anemia is associated with disease activity and systemic immune activation. Ferritin concentrations are increased in subjects with hypertension.

Peripheral Blood Toxicity of Topical 5-Fluorouracil on the Syrian Hamster Cheek Pouch

1975 ◽  
Vol 54 (3) ◽  
pp. 522-526
Author(s):  
Henry M. Cherrick ◽  
Bruce D. McKelvy
Keyword(s):  
Blood Cell ◽  
Cell Count ◽  
Peripheral Blood ◽  
Syrian Hamster ◽  
Significant Degree ◽  
Cheek Pouch ◽  
Blood Cell Count ◽  
Hamster Cheek Pouch ◽  
Toxicological Studies ◽  
Red Blood Cell Count

Toxicological studies on the peripheral blood after topical application of 5-fluorouracil to the buccal pouch of the Syrian hamster showed that a daily application of 10 μl (0.5 mg) was the maximum ideal dose for this animal. This dose did not depress to a significant degree the white blood cell count, red blood cell count, hemoglobin level, hematocrit value, or the peripheral differential blood counts after 14 daily applications. Doses of increased concentration either daily or periodically were less effective and toxic.

scholarly journals HEMATOLOGIC PROFILE OF LABORATORY RATS FED WITH BAKERY PRODUCTS

2017 ◽  
Vol 5 (5) ◽  
pp. 221-231
Author(s):  
Muhamed Katica ◽  
Nedzad Gradascevic
Keyword(s):  
Blood Cell ◽  
Red Blood Cells ◽  
Cell Count ◽  
Peripheral Blood ◽  
Blood Cells ◽  
Bakery Products ◽  
Blood Cell Count ◽  
Physiological Limits ◽  
Blood Smears ◽  
Peripheral Blood Smears

The laboratory rat, as important biomedical model, was often fed with unconventional diet usually made up of products from the bakery industry. Such diet consisted of insufficient caloric and nutritionally unbalanced meals could cause unreliable results in biomedical research. The study investigates the effects of malnutrition on the haematological profile of rats. The study is performed on Wistar male and female rats which were fed for 4 weeks exclusively with bakery products ad libidum. The following hematological parameters were observed in peripheral blood smears: red blood cell count, content of haemoglobin, haematocrit, MCV, MCH, MCHC, white blood cell count, differential blood count, diameter of red blood cells, as well as the presence of atypical forms of red blood cells. Despite there were no statistically significant differences in overall haematological results (p > 0.05, with > 0.05), the significant part of obtained results were below physiological limits (HGB, MCHC and MCH). Other haematological parameters, including white blood corpuscles were kept in physiological limits, except for mild neutrophils in males. Also, the forms of anulocytes and spherocytes were recorded in peripheral blood smears. The results indicated the beginning of normocytic hypochromic anaemia which was caused by unbalanced meals.

The impact of preapheresis white blood cell count on autologous peripheral blood stem cell collection efficiency and HSC infusion side effect rate

2018 ◽  
Vol 33 (3) ◽  
pp. 331-341 ◽  
Author(s):  
Araci. M. Sakashita ◽  
Andrea T. Kondo ◽  
Ana Paula H. Yokoyama ◽  
Sanny M. C. Lira ◽  
Carolina B. Bub ◽  
...  
Keyword(s):  
Stem Cell ◽  
Blood Cell ◽  
Cell Count ◽  
Peripheral Blood ◽  
Side Effect ◽  
Peripheral Blood Stem Cell ◽  
Collection Efficiency ◽  
Blood Cell Count ◽  
The Impact ◽  
Stem Cell Collection

scholarly journals Physiological changes of white blood cell count in peripheral blood of radiation workers.

Sangyo Igaku ◽  
1989 ◽  
Vol 31 (1) ◽  
pp. 18-19
Author(s):  
Seiichi AKIYAMA ◽  
Yoshihumi EDAGAWA ◽  
Atsumi KAWANAMI ◽  
Chiyosaburo NAKAGAWA ◽  
Hisashi URAI ◽  
...  
Keyword(s):  
Blood Cell ◽  
Cell Count ◽  
White Blood Cell Count ◽  
White Blood Cell ◽  
Peripheral Blood ◽  
Physiological Changes ◽  
Blood Cell Count ◽  
Radiation Workers
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