An obesrvational study to compare bala in Adana and visarga kaala with respect to physiological parameters

Introduction - Ayurveda gives utmost importance to the maintenance of positive health. Health and longevity in turn depends on bala or inherent strength of the individual. Bala is different in different seasons. Bala is examined as the capacity to do exercise, which is indicative of physical power of an individual. If the reflection of variation of bala on the basis of hematological parameters is identified, then it will provide many possibilities to modify the diet and lifestyle of healthy individuals in order to maintain health in all seasons. This work is a humble effort to analyze the seasonal variations in bala with respect to physiological objective parameters in the settings of Govt. Ayurveda medical college, Kannur, Kerala, India. Methods - In this study 30 healthy individuals between the age group of 20-30 were selected having similar vyayamasakthi- ie, based on the time taken to attain ardhasakthi lakshanas in treadmill test. First assessment was done in adanakaala. Their basic details, dasavidha pareeksha were taken before treadmill test. After 3 days of treadmill test, blood investigations were analyzed. The same procedure was done in visarga kaala also.Results - On the basis of analysis, the bala assessed by vyayamasakthi in visarga kaala was increased than adana kaala. Hemoglobin and HDL cholesterol were increased and serum calcium was decreased in visarga kaala. Considering vital parameters, increase in pulse rate, heart rate, systolic and diastolic BP was noticed in visarga kaala; all within physiological limits. Discussion – Bala was decreased in adana kaala due to the intensity of sunrays and intense dry wind. It causes decreased time to attain the ardhasakthi lakshana. Sweat occurs early. The bala was higher in visarga kaala compared to adaana kaala.

Diverging life cycle patterns of two Diamesa species (Diptera, Chironomidae) in High Arctic streams, Svalbard

The fauna of streams in the High Arctic, dominated by chironomids, is shaped by extreme environmental conditions that represent the physiological limits for benthic invertebrates. Despite their ecological importance, little is known of chironomid life histories, development strategies and the key abiotic drivers limiting larval growth in High Arctic streams. We investigated the larval development and growth in three High Arctic rivers with contrasting water sources, thermal regimes and nutrient characteristics. Populations of the larvae of Diamesa bohemani (Goetghebuer 1932) and Diamesa aberrata (Lundbeck 1898) from two sampling occasions in July and August 2016 were morphometrically analysed to determine life history patterns and instream productivity. Water temperature differences lead to diverging development patterns on local spatial scales. The lowest larval growth was in a groundwater/snowmelt fed stream with low food concentration and quality, suggesting that stream productivity is not primarily water source dependant, but is dependent on the nutrient supply. Glacially influenced streams are clearly more productive than previously assumed, resulting in comparable secondary production to groundwater/snowmelt-fed streams.

Morphological indicators of blood in cats with panleucopenia

Ukraine is one of the world leaders in the number of cats among the country's population, and one of the most common diseases is panleukopenia caused by a virus of the Parvoviridae family, which is extremely common among viral diseases and causes significant moral damage to owner animals. Therefore, given the relevance of this issue, the result of our study is to clarify, supplement and summarize the data on hematological and biochemical parameters of blood and erythrocytopoiesis in panleukopenia of cats. The development and improvement of modern methods of immunoprophylaxis and treatment can significantly reduce morbidity and mortality. The study was performed in veterinary clinics of Zhytomyr and Kyiv, blood for the study was taken from the superficial vein of the forearm Anterbrachium, medial subcutaneous vein or subcutaneous tibial vein Saphena. Diagnostic tests to confirm feline parvovirus were performed using rapid tests VetExpert and ELISA and PCR for the presence of parvovirus antigen in private veterinary laboratories “BioSoft” and LLC “Bald” in Kiev. The complex studies carried out indicated that in cats (n = 24) with panleukopenia, changes in the morphological and biochemical composition of the blood are characteristic. A deviation from physiological limits was found, which mainly characterize the functional state of the liver, namely, an increase in the content of total bilirubin (P ≤ 0.01) and total protein (P ≤ 0.01), the development of pancreatitis – taking into account an increase in glucose concentration (P ≤ 0.05) and α-amylase hyperenzymemia (P ≤ 0.001), kidney damage as indicated by an increase in creatinine concentration (P ≤ 0.001) and urea level (P ≤ 0.01). In the course of the research, a slight decrease in indicators of the main erythrocyte indices was established, namely, a decrease in MCHC (P ≤ 0.05), which indicates the development of anemia. As a result of an experimental study of the morphological parameters of blood, a complex pathogenesis of the disease with panleukopenia with multiple organ failure and the development of pathological immunosuppression and hepato-pancreatic-renal syndrome was established.

Influence of Bone Quality on the Use of Implant Prostheses with Intermediate Pontic: Three-dimensional Finite Element Method

Objective The present study aimed to observe the differences in the dissipation of the main minimum stresses with the use of a fixed pontic partial prosthesis supported by two regular length implants in cortical and medullary bone tissues of different qualities. Materials and Methods Experimental groups were as follows: QI (two regular length implants with fixed pontic partial prosthesis and bony qualities consistent with type I), QII (identical to QI, with bony qualities consistent with type II), and QIII (identical to QI, with bony qualities consistent with type III). All the groups were developed and analyzed in virtual simulation environment using AnsysWorkbench software. Results The results showed highest stress concentrations in the region of the turns of the implants, especially in the apical region surrounding the implants and most notably in those positioned in the posterior region, supporting the molars. In addition, comparing the cortical bone among the groups, the results revealed increasing levels of stress in the order of QI, QII, and QIII. Comparing the medullary bone among the groups, the results revealed increasing levels of stress in the order of QIII, QII, and QI. Conclusion It was concluded that greater stress disparity occurred in the comparison between groups QI and QIII. There was a higher TMiP in QI in the cortical bone, but considering the literature values, it would not pose risks to its physiological limits. The use of a pontic fixed partial prosthesis on two regular implants of type III bone quality may cause unfavorable physiological repercussions for the posterior implant apical medullary bone.

Environmental Thermal Stress Induces Neuronal Cell Death and Developmental Malformations in Reptiles

Every stage of organismal life history is being challenged by global warming. Many species are already experiencing temperatures approaching their physiological limits; this is particularly true for ectothermic species, such as lizards. Embryos are markedly sensitive to thermal insult. Here, we demonstrate that temperatures currently experienced in natural nesting areas can modify gene expression levels and induce neural and craniofacial malformations in embryos of the lizard Anolis sagrei. Developmental abnormalities ranged from minor changes in facial structure to significant disruption of anterior face and forebrain. The first several days of post-oviposition development are particularly sensitive to this thermal insult. These results raise new concern over the viability of ectothermic species under contemporary climate change. Herein, we propose and test a novel developmental hypothesis that describes the cellular and developmental origins of those malformations: cell death in the developing forebrain and disruption of normal facial induction due to disrupted Hedgehog signaling. Based on similarities in the embryonic response to thermal stress among distantly related species, we propose that this developmental hypothesis represents a common embryonic response to thermal insult among amniote embryos. Our results emphasize the importance of adopting a broad, multi-disciplinary approach that includes both lab and field perspectives when trying to understand the future impacts of anthropogenic change on animal development.

Epidemiological aspects, haematological and biochemical alterations in some gastrointestinal parasitic diseases of carnivores

Gastrointestinal parasites are widespread pathogenic agents and one of the main causes for mortality in young dogs and cats. Many of these zoonotic parasites are relevant in terms of public health. The presence of parasites in the animal organism causes local and general modifications in the various organs they parasitize or transit throughout their life cycle. The present study aimed to identify the most frequent gastrointestinal parasites of dogs and cats and to monitor the alterations that occur in terms of haematological and biochemical parameters. The studied animals, 25 dogs and three cats from Timiș and Caraș Severin counties, were brought to the On-call room of the University Clinics of the Faculty of Veterinary Medicine Timișoara. The laboratory methods that were used were the Willis flotation method, the Baerman larvoscopic method and the Lugol method. The haematological methods, namely flow cytometry, cytochemistry and spectrophotometry, were performed at Bioclinica Laboratories, on whole blood samples that were collected in EDTA or simple tubes. The studied animals were positive for Giardia, Cystoisospora, Dipylidium, Ancylostoma, Toxocara and Trichocephalus. The positivity rate was 57.14%, with prevalence rates according to the parasitic species ranging from 3.57% to 21.42%, with multiparasitism in 32.14%, and monoparasitism in 17.85%. The values recorded for red blood cells, haemoglobin and hematocrit followed the same trendmost of the animals being situated within physiological values, except for three dogs, that recorded values below the minimal level. In the case of MCH (mean corpuscular haemoglobin) and MCHC (mean corpuscular haemoglobin concentration) the values recorded for most dogs were within physiological limits, except for three dogs which overpassed the maximum level. Eosinophils were high in all dogs, which is a characteristic feature of parasitism. The serum urea concentrations revealed the fact that all for dogs that were taken into study had values above the maximum limit.

Predicting Global Terrestrial Biomes with Convolutional Neural Network

A biome is a major regional ecological community characterized by distinctive life forms and principal plants. Many empirical schemes such as the Holdridge Life Zone (HLZ) system have been proposed and implemented to predict the global distribution of terrestrial biomes. Knowledge of physiological climatic limits has been employed to predict biomes, resulting in more precise simulation, however, this requires different sets of physiological limits for different vegetation classification schemes. Here, we demonstrate an accurate and practical method to construct empirical models for biome mapping: A convolutional neural network (CNN) was trained by an observation-based biome map, as well as images depicting air temperature and precipitation. The trained model accurately simulated a global map of current terrestrial biome distribution. Then, the trained model was applied to climate scenarios toward the end of the 21st century, predicting a significant shift in global biome distribution with rapid warming trends. Our results demonstrate that the proposed CNN approach can provide an efficient and objective method to generate preliminary estimations of the impact of climate change on biome distribution. Moreover, we anticipate that our approach could provide a basis for more general implementations to build empirical models of other climate-driven categorical phenomena.

Warming, not CO2-acidified seawater, alters otolith development of juvenile Antarctic emerald rockcod (Trematomus bernacchii)

The combustion of fossil fuels is currently causing rapid rates of ocean warming and acidification worldwide. Projected changes in these parameters have been repeatedly observed to stress the physiological limits and plasticity of many marine species from the molecular to organismal levels. High latitude oceans are among the fastest changing ecosystems; therefore, polar species are projected to be some of the most vulnerable to climate change. Antarctic species are particularly sensitive to environmental change, having evolved for millions of years under stable ocean conditions. Otoliths, calcified structures found in a fish’s inner ear used to sense movement and direction, have been shown to be affected by both warming and CO2-acidified seawater in temperate and tropical fishes but there is no work to date on Antarctic fishes. In this study, juvenile emerald rockcod (Trematomus bernacchii) were exposed to projected seawater warming and CO2-acidification for the year 2100 over 28 days. Sagittal otoliths were analyzed for changes in area, perimeter, length, width and shape. We found ocean warming increased the growth rate of otoliths, while CO2-acidified seawater and the interaction of warming and acidification did not have an effect on otolith development. Elevated temperature also altered the shape of otoliths. If otolith development is altered under future warming scenarios, sensory functions such as hearing, orientation, and movement may potentially be impaired. Changes in these basic somatic abilities could have broad implications for the general capabilities and ecology of early life stages of Antarctic fishes.

VATS Sympathectomy for the management of Primary Hyperhidrosis: An experience at Aseer Central Hospital, Saudi Arabia.

Background: Hyperhidrosis is bilateral, symmetrical and profuse sweating beyond physiological limits of the body. It is an important disease that causes social and emotional disturbances. Conservative treatment has poor results and most of the patients end up in surgical remedy eventually. The choice of operation is Bilateral Sympathectomy which has excellent results. Objective: The aim of this study was to assess the demographic features of patients and to evaluate the outcome of VATS Sympathectomy. Study Design: Prospective Study. Setting: Aseer Central Hospital, Saudi Arabia. Period: September 2017 to March 2020. Material & Methods: Bilateral VATS with resection of sympathetic chain from T2 to T5 was done depending upon the area involved in hyperhidrosis. Results: 28 (58.3%) male and 20(41.6%) female patients with mean age 21 years (range 19 to 53) were documented. 40% of the patients related their condition to be familial. Most common site of involvement was combined Palmer Plant and Axillary in 26(54%) whereas isolated facial hyperhidrosis was the least involved area. Complication rate was 12% with no mortality recorded. Excellent results with 98% patient’s satisfaction was found. Conclusion: Bilateral VATS sympathectomy is the gold standard surgical treatment for Primary Hyperhidrosis with excellent results.

The effect of herbal supplements on development of internal organs and chemical composition of broilers muscles

The present article presents data on effectiveness of adding a phytobiotic feed additive into the diet of broiler chickens, either additionally or replacing the feed antibiotic in the chicken fodder. It has been established that the introduction of a phytobiotic feed additive into the broilers’ diet, both additionally and by replacing the feed antibiotic, provided positive effect on poultry meat quality and gave no negative effect on development of internal organs. By the end of fattening the relative weight of heart, lungs, kidneys, gizzard and intestines in broilers, which consumed the antibiotics-free diet with addition of researched preparation, was higher than in the control group and in the 1st experimental group. At the same time the length of the intestine in researched group significantly exceeded the control group parameters. These changes ranged within the physiological norm, which may indicate the best detoxification capabilities of the chicken body and the activation of enhanced intestinal absorption function. Additional use of the experimental feed additive in formulation of feed for broiler chickens was accompanied by a decrease in total amount of amino acids in broilers’ pectoral and leg muscles within acceptable physiological limits. At the same time, a significant decrease, compared with the control parameters, was noted in relation to content of histidine and isoleucine in pectoral muscles, and content of proline in leg muscles. The use of the researched additive as a substitute for a feed antibiotic in composition of mixed feed for broilers decreased the total amount of amino acids in broilers’ breast muscle, compared with the control group, and increased level of amino acids in leg muscles. The significant decrease in content of histidine and arginine in the pectoral muscles and proline in the leg muscles was noted. The observed changes varied within acceptable physiological norm. In the experimental groups the energy value of meat was increased.