Challenges and opportunities of 3D-skin models: the way forward for assessing chemical sensitizers?

2021 ◽  
Vol 350 ◽  
pp. S34
Author(s):  
S. Gibbs
2021 ◽  
pp. 405-436
Author(s):  
George K. Shinomol ◽  
Revathi K. Bhanu

2021 ◽  
Vol 127 (1) ◽  
pp. 119-134
Author(s):  
Jay Szpilka

While the subject of women’s activity in historical and contemporary punk scenes has attracted significant attention, the presence of trans women in punk has received comparatively little research, in spite of their increasing visibility and long history in punk. This article examines the conditions for trans women’s entrance in punk and the challenges and opportunities that it offers for their self-assertion. By linking Michel Foucault’s notion of parrhesia with the way trans women in punk do their gender, an attempt is made at showing how the embodied experience of a trans woman making herself heard from the punk stage can serve as a site of ‘gender pluralism’.


2021 ◽  
Author(s):  
◽  
Hoa Thi Hai Vu

<p>Although there is a large literature on ASEAN regionalism, comparatively little attention has been devoted to Southeast Asia’s efforts to build a shared social and cultural community. This thesis examines how the ASEAN Socio-Cultural Community (ASCC) is understood in ASEAN and explores challenges that stand in the way of the Community being realized by its 2015 deadline. The study reviews the origins and response to the ASCC at both the regional level, and at the national level through a case-study of Vietnam’s participation. It argues that although the ASCC is an important component of the ASEAN Community building process and member states have proclaimed their determination to realize the ASCC by 2015, the reality in ASEAN with its “unity in diversity” and “ASEAN Way” norms, means there are many obstacles in the way. Divergent national interests and priorities have led to different priorities in designing and implementing the ASCC Blueprint in the period 2009-2015. The thesis concludes by speculating about the likely scenario for ASCC implementation. It argues that in 2015, the most likely scenario for the ASCC is one in which a nascent ASCC will be formed but with only some of its components in place. ASEAN needs a longer journey to realize its aspiration of a shared socio-culture community.</p>


2020 ◽  
Vol 2 (2) ◽  
pp. 273-282
Author(s):  
Asok Kumar Sarkar ◽  
Mamunur Rahman ◽  
Manohar Pawar

In the light of the unique experiences of the 7th ICSDAP Conference, this article includes a brief background, details of activities, challenges and opportunities, and outputs and outcomes. Our experiences and reflections suggest that organising international conferences to bring social development scholars together to deliberate on mutual areas of research and practice interests undoubtedly contributes to critical examination and dissemination of knowledge, at least to some extent. In addition, what is equally important, the process and experience of organising conferences appear to enhance our and host organisation’s learning and capacity-building, yielding benefit for everyone to build a better future by overcoming all the odds.


2019 ◽  
Vol 11 (13) ◽  
pp. 3691 ◽  
Author(s):  
Stephan Grapentin ◽  
Maureen Ayikoru

This study examines recent developments in destination assessment and certification as a basis for identifying challenges and benefits they engender, from tourist and tourism organizations’ perspectives. It uses online surveys and semi-structured interviews to collect primary data from prospective tourists and key informants on destination assessment and certification. The findings highlight the strengths and weaknesses of schemes currently in use, including various factors that might influence their future development. Specifically, the study finds that destination assessment and certification are affected by four key issues, namely, practicability, reliability, visibility, and (un)availability of incentives. It concludes that the manifestation of these issues and their ensuing complexity affect the way in which tourists and tourism destinations engage with destination assessment and certification. This, therefore, delimits the inherent opportunities and constraints within such schemes.


2020 ◽  
Vol 42 (1) ◽  
pp. 8-28
Author(s):  
Jerome de Groot

This study of the genealogy and biotech company Ancestry analyzes the ways in which the organization has evolved over the past few years. Ancestry is difficult to categorize as a corporate entity. The company trades in servicing both “traditional” types of history (genealogical records) and, more recently, biotech-based investigation through the use of DNA sequencing. Ancestry is highly influential in the way that millions of people around the world access the past. Given this, the company’s shifts in focus are of great interest. Through considering various new elements of the way that Ancestry functions, and illustrating that this complexity is foundational to its purpose, the article suggests the company is redefining what a public historian or public historical institution might be, adding a scientific dimension to historical data and also acting to present a particular model of the past through its advertising campaigns. The article suggests that public history’s models for considering such protean organizations are in need of attention, and the complexity of such a company demonstrates new challenges and opportunities for scholars in the field.


2016 ◽  
Vol 56 ◽  
pp. 3-7 ◽  
Author(s):  
Catherine Amlie-Lefond ◽  
Michael J. Rivkin ◽  
Neil R. Friedman ◽  
Timothy J. Bernard ◽  
Michael Morgan Dowling ◽  
...  

2014 ◽  
Vol 25 (22) ◽  
pp. 3461-3465 ◽  
Author(s):  
Sophie Dumont ◽  
Manu Prakash

Mechanical force organizes life at all scales, from molecules to cells and tissues. Although we have made remarkable progress unraveling the mechanics of life's individual building blocks, our understanding of how they give rise to the mechanics of larger-scale biological structures is still poor. Unlike the engineered macroscopic structures that we commonly build, biological structures are dynamic and self-organize: they sculpt themselves and change their own architecture, and they have structural building blocks that generate force and constantly come on and off. A description of such structures defies current traditional mechanical frameworks. It requires approaches that account for active force-generating parts and for the formation of spatial and temporal patterns utilizing a diverse array of building blocks. In this Perspective, we term this framework “emergent mechanics.” Through examples at molecular, cellular, and tissue scales, we highlight challenges and opportunities in quantitatively understanding the emergent mechanics of biological structures and the need for new conceptual frameworks and experimental tools on the way ahead.


2016 ◽  
Vol 37 (2) ◽  
pp. 33-49 ◽  
Author(s):  
Hanne Bruun

Abstract This article presents and discusses the communicative behaviour in the continuity texts produced by public service television providers in Denmark in the digital era. Based on a case study of the two main channels, DR and TV 2, the article argues that, after previous trends towards convergence in the way the two providers communicate, the present developments exhibit a divergence. Three major differences are found in the efforts to (1) hold on to and ‘herd’ the viewers within the scope of products and platforms, (2) strengthen the provider–viewer relationship, and (3) stand out with a distinctive set of institutional values. The findings are interpreted as a consequence of the challenges and opportunities facing the providers in terms of funding and in terms of meeting public service obligations, in a situation of tension between a traditional linear model of broadcasting and an emerging non-linear model.


Architecture ◽  
2021 ◽  
Vol 1 (1) ◽  
pp. 3-4
Author(s):  
Avi Friedman

The outset of the 21st century launched a “perfect storm” of societal and technological challenges and opportunities that stand to affect the way architects will design and builders construct in the next decades [...]


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