Clinical Application of Evoked Electromyography (Frequency Depression Curve) in the Diagnosis and Treatment of Vertigo

1980 ◽  
Vol 7 (3) ◽  
pp. 125-139
Author(s):  
Takashi Matsunaga ◽  
Shin-Ichi Okumura ◽  
Toru Matsunaga ◽  
Toshi Naito
Keyword(s):  
Clinical Application ◽  
Diagnosis And Treatment ◽  
Depression Curve ◽  
Evoked Electromyography

scholarly journals Promising Applications of Nanoparticles in the Treatment of Hearing Loss

2021 ◽  
Vol 9 ◽  
Author(s):  
Zilin Huang ◽  
Qiang Xie ◽  
Shuang Li ◽  
Yuhao Zhou ◽  
Zuhong He ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Hearing Loss ◽  
Inner Ear ◽  
Drug Delivery System ◽  
Clinical Application ◽  
Delivery System ◽  
Diagnosis And Treatment ◽  
Biological Research ◽  
Medical Applications ◽  
Traditional Treatment

Hearing loss is one of the most common disabilities affecting both children and adults worldwide. However, traditional treatment of hearing loss has some limitations, particularly in terms of drug delivery system as well as diagnosis of ear imaging. The blood–labyrinth barrier (BLB), the barrier between the vasculature and fluids of the inner ear, restricts entry of most blood-borne compounds into inner ear tissues. Nanoparticles (NPs) have been demonstrated to have high biocompatibility, good degradation, and simple synthesis in the process of diagnosis and treatment, which are promising for medical applications in hearing loss. Although previous studies have shown that NPs have promising applications in the field of inner ear diseases, there is still a gap between biological research and clinical application. In this paper, we aim to summarize developments and challenges of NPs in diagnostics and treatment of hearing loss in recent years. This review may be useful to raise otology researchers’ awareness of effect of NPs on hearing diagnosis and treatment.

scholarly journals Clinical diagnosis and treatment of throat foreign bodies under video laryngoscopy

2020 ◽  
Vol 48 (7) ◽  
pp. 030006052094049
Author(s):  
Chuanyao Lin ◽  
Dingding Liu ◽  
Han Zhou ◽  
Xiaoli Zhang ◽  
Ling Lu ◽  
...  
Keyword(s):  
Clinical Diagnosis ◽  
Clinical Application ◽  
Foreign Bodies ◽  
Diagnosis And Treatment ◽  
Video Laryngoscopy ◽  
Fish Bones ◽  
Drum Tower Hospital

Objective This study was designed to explore the clinical application of video laryngoscopy in the diagnosis and treatment of throat foreign bodies (FBs). Method In total, 1572 patients diagnosed with throat FBs at the Department of Otolaryngology of Nanjing Drum Tower Hospital were retrospectively analysed. The covariables collected were the time from FB ingestion to admission, age, sex, duration of admission, and site of impaction. Result The most common FBs were fish bones, which accounted for 1446 (91.98%) of 1572 FBs. Among all 1572 FBs, 1004 (63.87%) were successfully removed by video laryngoscopy without complications. A shorter duration of admission was associated with a higher diagnostic rate under video laryngoscopy. The diagnostic rate of sharp FBs was significantly higher than that of non-sharp FBs. The most common sites of throat FBs were the tongue root (42.29%), epiglottic vallecula (19.40%), tonsil (18.21%), and piriform fossa (10.65%). Conclusion Video laryngoscopy is a powerful tool for the diagnosis and treatment of throat FBs, allowing for identification of rare locations of FBs as well as refractory FBs.

scholarly journals Clinical Application of Serum Inflammatory Factors Combined With Dynamic Detection in the Diagnosis and Treatment of Neonatal Sepsis

2021 ◽  
Author(s):  
Dahong SUN ◽  
Qing WANG ◽  
Xiaoyan ZHANG ◽  
Xiuzhen ZHAO ◽  
Haiyan ZHANG ◽  
...  
Keyword(s):  
Virus Infection ◽  
Clinical Application ◽  
Neonatal Sepsis ◽  
Venous Blood ◽  
Diagnosis And Treatment ◽  
Sepsis Group ◽  
Inflammatory Factors ◽  
Infection Group ◽  
Serum Crp ◽  
Combined Detection

Background: To investigate the clinical application value of the combination of the inflammatory factors and dynamic detection in the diagnosis and treatment of neonatal sepsis by detecting serum inflammatory factor Creactive protein (CRP), procalcitonin (PCT), and interleukin-6 (IL-6) levels before and after treatment of neonatal infection. Methods: A total of 138 neonates with different degrees of infection were randomly enrolled, including 88 cases in the sepsis group and 50 cases in the virus infection group. Another 50 non-infected newborns in the same period were enrolled as the normal control group. Venous blood of all subjects for CRP, PCT, IL-6 detection, and send bacterial blood culture for sepsis and virus infection groups were collected at the same time. In the recovery period, venous blood of children in sepsis group was collected again to review CRP, PCT, IL-6, and differences in each test index of each group were compared. Results: The serum CRP, PCT, IL-6 levels in the sepsis group were significantly higher than those in the virus infection group (all P <0.05); serum CRP, PCT, IL-6 levels in the sepsis group were significantly lower than before treatment (P <0.05); the sensitivity and accuracy of the combined detection of indicators for the diagnosis of neonatal sepsis were significantly improved. Conclusion: The inflammatory factors CRP, PCT, and IL-6 are closely related to the occurrence and development of neonatal sepsis. Combined detection can effectively improve the diagnostic accordance rate, which is beneficial to the early diagnosis and early clinical intervention of neonatal sepsis.

scholarly journals Crosstalk Among circRNA/lncRNA, miRNA, and mRNA in Osteoarthritis

2021 ◽  
Vol 9 ◽  
Author(s):  
Hui Kong ◽  
Ming-Li Sun ◽  
Xin-An Zhang ◽  
Xue-Qiang Wang
Keyword(s):  
Adverse Effects ◽  
Clinical Application ◽  
Protein Translation ◽  
Diagnosis And Treatment ◽  
Joint Disease ◽  
Biological Functions ◽  
Biological Targets ◽  
Incidence And Mortality ◽  
Different Types ◽  
New Biomarkers

Osteoarthritis (OA) is a joint disease that is pervasive in life, and the incidence and mortality of OA are increasing, causing many adverse effects on people’s life. Therefore, it is very vital to identify new biomarkers and therapeutic targets in the clinical diagnosis and treatment of OA. ncRNA is a nonprotein-coding RNA that does not translate into proteins but participates in protein translation. At the RNA level, it can perform biological functions. Many studies have found that miRNA, lncRNA, and circRNA are closely related to the course of OA and play important regulatory roles in transcription, post-transcription, and post-translation, which can be used as biological targets for the prevention, diagnosis, and treatment of OA. In this review, we summarized and described the various roles of different types of miRNA, lncRNA, and circRNA in OA, the roles of different lncRNA/circRNA-miRNA-mRNA axis in OA, and the possible prospects of these ncRNAs in clinical application.

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