scholarly journals GENDER AND RACE DIFFERENCES IN AGING-RELATED ALTERATION IN MYOCARDIAL SYSTOLIC FUNCTION ASSESSED BY 2D SPECKLE TRACKING ECHOCARDIOGRAPHY OVER A 20 YEAR FOLLOW-UP: THE CARDIA STUDY

2015 ◽  
Vol 65 (10) ◽  
pp. A1206 ◽  
Author(s):  
Chike Nwabuo ◽  
Eui-Young Choi ◽  
Bharath Ambale Venkatesh ◽  
Satoru Kishi ◽  
Andre L. Almeida ◽  
...  
2019 ◽  
pp. 83-89
Author(s):  
Walid Sallam ◽  
AmalM.Ayoub ◽  
Mona I. AboulSoud ◽  
Mohamed Ismail ◽  
Mostafa A.Elnozahi ◽  
...  

Background: The right ventricle (RV) shows good long-term recovery in STEMI patients treated by primary PCI (PPCI), but, in the short term, RV involvement has a worse prognosis. Acute cardiogenic shock due to acute RV failure is equal in mortality to that due to acute left ventricular failure. The assessment of RV structure and function by echocardiography improved by advances including tissue doppler, strain, and three-dimensional (3D) imaging techniques. Methods: In PPCI treated patients, the early recovery of the RV was studied using 2D speckle tracking Echocardiography. Results: The study enrolled 120 patients, 40 anterior STEMI patients, 40 inferior STEMI patients and 40 adult healthy controls. All patients presented to Ainshams University hospitals cath. lab for PPCI as per guidelines. We excluded patients with known history of any disease affecting the RV. 102 males (85%) and 18 females (15%) were studied. The mean age of the anterior group was (53 ± 9 years) and of the inferior group was (54 ± 10 years). Full transthoracic echocardiography (TTE) examination including assessment of the RV systolic function by fractional area change (FAC), tricuspid annulus plane systolic excursion (TAPSE), Systolic TV annular velocity (S’) and RV free wall longitudinal strain. All echocardiographic measures were repeated after 3-6 months. Nine patients died during the follow up period. 54 (67.5%) patients had an impaired left evntricular ejection fraction (LVEEF) in the baseline study which significantly improved in the follow up (39.4%), (p value 0.001). A significant deterioration of the diastolic function was detected, (p value 0.002). A significant reduction of the Left atrial volume index (LAVI) was detected (p value 0.006). Also, a significant improvement of the RV FAC (p value 0.01) and TAPSE (p value 0.047). There was a significant deterioration of the apical RV free wall strain (P value 0.018). Conclusions: Right ventricular systolic function may be normal after acute STEMI treated by PPCI, but with 2D strain echocardiography, subclinical RV systolic dysfunction can be detected. So, it’s recommended to assess the global & segmental RV functions after acute MI with the conventional parameters as well as by 2D speckle tracking derived strain. Keywords: Acute MI; TTE; FAC; TAPSE S’; RV free wall GLS


2019 ◽  
Vol 11 (4) ◽  
pp. 309-313
Author(s):  
Atoosa Mostafavi ◽  
Yaser Tase Zar ◽  
Farahnaz Nikdoust ◽  
Seyed Abdolhossein Tabatabaei

Introduction: In light of previous studies reporting the significant effects of preeclampsia on cardiac dimensions, we sought to evaluate changes in the left ventricular (LV) systolic and diastolic functions in patients with preeclampsia with a view to investigating changes in cardiac strain. <br /> Methods: This cross-sectional study evaluated healthy pregnant women and pregnant women suffering from preeclampsia who were referred to our hospital for routine healthcare services. LV strain was measured by 2D speckle-tracking echocardiography. <br /> Results: Compared with the healthy group, echocardiography in the group with preeclampsia showed a significant increase in the LV end-diastolic diameter (47.43 ± 4.94 mm vs 44.84 ± 4.30 mm; P = 0.008), the LV end-systolic diameter (31.16 ± 33.3 mm vs 29.20 ± 3.75 mm; P = 0.008), and the right ventricular diameter (27.93 ± 1.71 mm vs 24.53 ± 23.3; P = 0.001). The mean global longitudinal strain was -18.69 ± 2.8 in the group with preeclampsia and -19.39 ± 3.49 in the healthy group, with the difference not constituting statistical significance (P = 0.164). The mean global circumferential strain in the groups with and without preeclampsia was -20.4 ± 12.4 and -22.68 ± 5.50, respectively, which was significantly lower in the preeclampsia group (P = 0.028).<br /> Conclusion: The development of preeclampsia was associated with an increase in the right and left ventricular diameters, as well as a decrease in the ventricular systolic function, demonstrated by a decline in global circumferential strain.


2013 ◽  
Vol 2013 ◽  
pp. 1-9 ◽  
Author(s):  
Felicitas Escher ◽  
Mario Kasner ◽  
Uwe Kühl ◽  
Johannes Heymer ◽  
Ursula Wilkenshoff ◽  
...  

Background. The diagnosis of acute myocarditis (AMC) and inflammatory cardiomyopathy (DCMi) can be difficult. Speckle tracking echocardiography with accurate assessments of regional contractility could have an outstanding importance for the diagnosis.Methods and Results.N=25patients with clinically diagnosed AMC who underwent endomyocardial biopsies (EMBs) were studied prospectively. Speckle tracking imaging was examined at the beginning and during a mean follow-up period of 6.2 months. In the acute phase patients had markedly decreased left ventricular (LV) systolic function (mean LV ejection fraction (LVEF)40.4±10.3%). At follow-up inn=8patients, inflammation persists, correlating with a significantly reduced fractional shortening (FS,21.5±6.0%) in contrast to those without inflammation in EMB (FS32.1±7.1%,P<0.05). All AMC patients showed a reduction in global systolic longitudinal strain (LS,−8.36±−3.47%) and strain rate (LSR,0.53±0.29 1/s). At follow-up, LS and LRS were significantly lower in patients with inflammation, in contrast to patients without inflammation (−9.4±1.4versus−16.8±2.0%,P<0.0001;0.78±0.4versus1.3±0.3 1/s). LSR and LS correlate significantly with lymphocytic infiltrates (for CD3r=0.7,P<0.0001, and LFA-1r=0.8,P<0.0001).Conclusion. Speckle tracking echocardiography is a useful adjunctive assisting tool for evaluation over the course of intramyocardial inflammation in patients with AMC and DCMi.


2014 ◽  
Vol 12 (1) ◽  
Author(s):  
Sebastian Spethmann ◽  
Karl Rieper ◽  
Gabriela Riemekasten ◽  
Adrian C Borges ◽  
Sebastian Schattke ◽  
...  

2021 ◽  
Vol 23 (Supplement_D) ◽  
Author(s):  
Mohamed ElGendi ◽  
Mohamed Ayman ◽  
Mohamed Sadaka ◽  
Gehan Magdi

Abstract Aim The aim was to evaluate left ventricular (LV) systolic function in patients with isolated mitral stenosis (MS) using 2D speckle tracking echocardiography. Methods 24 patients (39.50 ± 5.55 years, 17 females) with isolated MS (MVA: 1.35 ± 0.16 cm2) with preserved LV systolic function and sinus rhythm were compared to 12 matched healthy control subjects (36.42 ± 5.99 years, 8 females). Conventional echocardiography was performed to both groups. Longitudinal strain and Circumferential strain echocardiography were obtained. Peak systolic strain was measured from the mean strain profile for a total of 17 segments of the LV for the longitudinal strain and 16 segments for the circumferential strain. Global longitudinal (G.L.) and circumferential strain (G.C.) were calculated separately as the average of the sum of the studied segments. Results The global longitudinal strain of the cases group ranged from -11 – -17% with a mean value of -14.67 ± -1.69% and that of the control group ranged from -15 – -20% with a mean value of -17.83 ± -1.53% with a statistically significant difference between the two groups. In our study, there was a negative but non-significant correlation between LV GLSS and LA diameter (r = -0.054, p = 0.802), Echo score (r = -0.018, p = 0.933) and PASP (r = 0.021, p = 0.922) in patients group. Also, the correlation was negative but non-significant between LV GCSS and LA diameter (r = -0.142, p = 0.507), Echo score (r = -0.200, p = 0.349) and PASP (r = -0.155, p = 0.471) in patients group. Conclusion • 2D speckle tracking echocardiography can detect subclinical LV systolic dysfunction which cannot be recognized by 2D conventional echocardiography. • Isolated rheumatic MS may be associated with subclinical LV systolic dysfunction.


2018 ◽  
Vol 2018 ◽  
pp. 1-5
Author(s):  
Gijs E. De Maat ◽  
Yoran M. Hummel ◽  
Alberto Pozzoli ◽  
Ottavio R. Alfieri ◽  
Michiel Rienstra ◽  
...  

Objective. Thoracoscopic surgical pulmonary vein isolation (sPVI) has been added to the treatment of atrial fibrillation (AF), showing excellent efficacy outcomes. However, data on right ventricular (RV) function following sPVI has never been studied. Our aim was to investigate RV function following sPVI and compare it to patients who underwent endocardial cryoballoon PVI. Methods. 25 patients underwent sPVI and were pair-matched according to age, sex, and AF type with 21 patients who underwent cryoballoon PVI. RV function was measured using tricuspid annular plane systolic excursion (TAPSE) and RV strain with 2D speckle tracking. Echocardiography was performed at baseline and at median 6-month follow-up. Results. Age was 54 ± 9 years and 84% were male; AF was paroxysmal in 92%. In the sPVI group, TAPSE was reduced with 31% at follow-up echocardiography (p<0.001) and RV strain showed a 25% reduction compared to baseline (p=0.018). In the control group, TAPSE and RV strain did not change significantly (−3% and +13%, p=0.410 and p=0.148). Change in TAPSE and RV strain was significantly different between groups (p≤0.001 and p=0.005). Conclusions. This study shows that RV function is significantly decreased following sPVI. This effect was not observed in the cryoballoon PVI control group.


2020 ◽  
Vol 21 (Supplement_1) ◽  
Author(s):  
E Melillo ◽  
G Palmiero ◽  
A Ferro ◽  
G Carlomagno ◽  
L Dell"urzo ◽  
...  

Abstract Funding Acknowledgements none Background In degenerative mitral regurgitation (DMR), left ventricle (LV) and left atrium (LA) undergo progressive volume overload leading to chamber remodelling and dysfunction in advanced stages. Speckle tracking echocardiography (STE) is an estabilished technique able in detecting subclinical LA and LV dysfunction in this setting. However data are lacking on the relationship of LA and LV function in DMR patients. Purpose Our aim was to assess LA function in patients with DMR and to explore its possible correlations with LV dimensions and systolic function. Methods We enrolled 95 patients with mild to severe DMR, dichotomizing them on the basis of mitral regurgitation severity (DMR 1-2: mild and mild-to-moderate MR; DMR 3-4: at least moderate to severe MR). LA function was assesed with 2D speckle tracking echocardiography. Results The two groups were well matched. DMR 3-4 group (n= 48) showed higher LA and LV volumes, lower right ventricle longitudinal systolic function and higher values of systolic pulmonary pressure. There was not significant difference in LV ejection fraction (LVEF) and global longitudinal strain (GLS). Among LA function indexes, only peak systolic reservoir strain was significantly reduced in DMR 3-4 group (21,9± 6,2% vs 24,7± 7,2% ; p= 0,04). Then population study was further divided in two groups according to the presence (LA dys+) or absence (LA dys-) of LA dysfunction, defined as reservoir strain values below the median [median 23.7%; LAdys- group (n. 49), LAdys+ group (n.46) ]. At the comparison of continuous variables (Tab.1), LAdys+ group showed larger LV end systolic diameter and more impaired LVEF (60,9± 9,8% vs 65,4± 4,8%; p: 0,004) and GLS (20,04 ± 3,7% vs 23,53 ± 2,7%; p &lt;0,001). Conclusions Our data showed that LA reservoir strain was impaired in patients with moderate to severe DMR. Furthermore, patients with LA dysfunction showed reduced LVEF and GLS values. Consequently, LA dysfunction assessed with STE may be a novel marker of early LV systolic dysfunction in patients with degenerative mitral regurgitation. Tab.1 LAdysf- (n = 49) LAdysf+ (n = 46) P value LVESD (mm) 31.78 ± 4.1 34.74 ± 7.6 0.020 LAVI (mL/mq) 44.5 ± 15.1 55.6 ± 25.6 0.015 TAPSE (mm) 26.30 ± 3.96 24.02 ± 3.31 0.004 sPAP (mmHg) 31.4 ± 7.0 36.4 ± 10.9 0.009 LVEF (%) 65.4 ± 4.8 60.9 ± 9.8 0.004 GLS (%) 23.5 ± 2.7 20.0 ± 3.7 &lt;0.001 Comparison of continuous variables between patients with and without LA dysfunction.


Sign in / Sign up

Export Citation Format

Share Document