POSTPROCEDURAL DECREASE IN SYSTOLIC BLOOD PRESSURE IS ASSOCIATED WITH AN INCREASED RISK OF CONTRAST-INDUCED NEPHROPATHY FOR PATIENTS UNDERGOING ELECTIVE PERCUTANEOUS CORONARY INTERVENTION

2018 ◽  
Vol 71 (11) ◽  
pp. A1122
Author(s):  
Pengyuan Chen ◽  
Ning Tan ◽  
Yong Liu ◽  
Hualong Li
Keyword(s):  
Blood Pressure ◽  
Percutaneous Coronary Intervention ◽  
Systolic Blood Pressure ◽  
Coronary Intervention ◽  
Contrast Induced Nephropathy ◽  
Elective Percutaneous Coronary Intervention ◽  
Increased Risk ◽  
Percutaneous Coronary

scholarly journals P0118ANEMIA AS A RISK FACTOR FOR CONTRAST-INDUCED NEPHROPATHY

2020 ◽  
Vol 35 (Supplement_3) ◽  
Author(s):  
Emna Chaabouni ◽  
Hela Jbali ◽  
Najjar Mariem ◽  
Mzoughi Khadija ◽  
Zouaghi Karim
Keyword(s):  
Percutaneous Coronary Intervention ◽  
Coronary Angiography ◽  
Strong Predictor ◽  
Coronary Intervention ◽  
Severe Anemia ◽  
Contrast Induced Nephropathy ◽  
Female Patients ◽  
Increased Risk ◽  
Percutaneous Coronary ◽  
Male Patients

Abstract Background and Aims Contrast-induced nephropathy is a potentially serious complication following coronary angiography and percutaneous coronary intervention . The association between severity of anemia and Contrast-induced nephropathy following coronary angiography is not well-established. In this prospective study, we aimed at assessing the association of anemia of various severity with the risk of Contrast-induced nephropathy in patients who underwent coronary angiography Method We prospectively enrolled 158 patients who underwent coronary angiography with or without percutaneous coronary intervention from December 2017 to February 2018 at a cardiology department . CIN was defined as an increase in serum creatinine level >25% or 0.5 mg/dL after 48 hours and anemia was defined as a value of Hb level ≤ 13 g/dl in male patients or ≤ 12 g/dl in female patients. Patients were stratified into three subgroups—mild (11.1 to 13.0 g/dL) in male patients and (11.1 to 12.0 g/dL) in female patients, moderate (9.1 to 11.0 g/dL) and severe anemia (7.0 to 9.0 g/dL). we used a multivariable logistic-regression model. Results 158 patients (females = 36.1%, mean age 60.0 ± 11 years) who underwent coronary angiography, 15 (9,5%) developed Contrast-induced nephropathy . Presence of anemia was associated with increased risk of developing Contrast-induced nephropathy (OR = 3.04, 95% confidence interval [CI] = 1.03 to 8.96, p= 0,043). Risk of Contrast-induced nephropathy was increasingly higher with increasing severity of the anemia; mild (OR = 1.67, 95% CI = 1.38 to 2.17, p=0,036), moderate (OR = 3.3, 95% CI = 0.61 to 10.6, p=0,028) .There was no patient with severe anemia. Conclusion In conclusion, severity of anemia is a strong predictor of CIN following coronary angiography.

scholarly journals Omega-3 Supplementation in the Prevention of Contrast Induced Nephropathy in Patients Undergoing Elective Percutaneous Coronary Intervention: A Randomized Placebo-Controlled Trial

2019 ◽  
Vol 9 (2) ◽  
pp. 307-313 ◽  
Author(s):  
Farzaneh Foroughinia ◽  
Mahtabalsadat Mirjalili ◽  
Ehsan Mirzaei ◽  
Alireza Oboodi
Keyword(s):  
Percutaneous Coronary Intervention ◽  
Cystatin C ◽  
Coronary Intervention ◽  
Protective Role ◽  
Control Group ◽  
Omega 3 ◽  
Contrast Induced Nephropathy ◽  
Elective Percutaneous Coronary Intervention ◽  
Percutaneous Coronary ◽  
Hydration Therapy

Purpose: Contrast-induced nephropathy (CIN) is the third cause of hospital-acquired renal failure and is associated with significant morbidity and mortality. Several studies have revealed the protective role of omega-3 in prevention and treatment of some kidney injuries. This study was conducted to examine the effect of omega-3 supplementation on the markers of renal function and to evaluate its potential in the prevention of CIN in patients undergoing elective percutaneous coronary intervention (PCI). Methods: In this double-blind, randomized clinical trial, 85 eligible patients scheduled for PCI was randomly divided into omega-3 (a single 3750 mg dose of omega-3 as well as routine hydration therapy within 12 hours before PCI) or control (placebo plus routine hydration therapy) groups. Serum creatinine (SCr) and cystatin C levels were measured at baseline and 24 hours after PCI. Results: Our results indicated that post- PCI cystatin C levels were significantly decreased in the omega-3 group compared to the control group (P < 0.001). Although less upward manner was seen in the level of 24-hour creatinine in the omega-3 group, it did not reach the significance level (P = 0.008). Conclusion: The positive effect of omega-3 on cystatin C levels showed that it may have a protective role in the prevention of CIN in post-PCI patients with normal kidney function. However, to better assess this effect, it is highly recommended to design future studies with higher doses and longer duration of therapy with omega-3 plus long-term follow up.

Predictive value of plasma volume status for contrast-induced nephropathy in patients with heart failure undergoing elective percutaneous coronary intervention

2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
C He ◽  
K Lin ◽  
H Chen ◽  
H He ◽  
J Yang ◽  
...  
Keyword(s):  
Heart Failure ◽  
Percutaneous Coronary Intervention ◽  
Plasma Volume ◽  
Predictive Value ◽  
Coronary Intervention ◽  
Volume Status ◽  
Contrast Induced Nephropathy ◽  
Elective Percutaneous Coronary Intervention ◽  
Percutaneous Coronary ◽  
Patients With Heart Failure

Abstract   Predictive value of plasma volume status for contrast-induced nephropathy in patients with heart failure undergoing elective percutaneous coronary intervention. Objective Contrast-induced nephropathy (CIN) remains a common complication of coronary procedure and increases poor outcomes, especially in patients with heart failure. Plasma volume expansion relates to worsening prognosis of heart failure. We hypothesised that calculated plasma volume status (PVS) might provide predictive utility for contrast-induced nephropathy in patients with heart failure undergoing elective percutaneous coronary intervention (PCI). Methods We enrolled 441 patients with heart failure undergoing PCI from 2012 to 2018. Pre-procedural PVS was calculated by comparing actual plasma volume (aPV) derived from the Hakim formula to ideal plasma volume (iPV). CIN was defined as an absolute SCr increase ≥0.5 mg/dl within 72h of contrast medium exposure. We assessed the association between PVS and risk of contrast-induced nephropathy in patients with heart failure undergoing elective PCI. Results In 441 patients, 28 (6.3%) patients developed CIN. The median pre-procedural PVS was −0.02 (−0.09–0.05). The best cutoff value of PVS for predicting CIN was 0.04 with 64.5% sensitivity and 75.5% specificity according to the ROC analysis (C statistic = 0.718; 95% CI: 0.674–0.760),of which predictive value is similar to NT-proBNP (C statistics 0.721 vs. 0.773, P=0.355). After adjusting for potential confounding risk factors, multivariable analysis demonstrated that PVS &gt;0.04 (OR=3.142, 95% CI: 1.185–8.332, P&lt;0.05) and NT-proBNP &gt;4518pg/ml (OR=7.591, 95% CI: 2.886–19.968, P&lt;0.05)were strong independent predictors of CIN. Conclusion Pre-procedural PVS is an independent risk factor for predicting CIN markedly, of which predictive value is comparable to BNP and also independent of BNP. The best cutoff point of PVS for predicting CIN was 0.04. ROC for PVS and NT-proBNP to predict CIN Funding Acknowledgement Type of funding source: None

Sign in / Sign up

Export Citation Format

Share Document