Long-term effects of topiramate on bipolar mood instability, weight change and glycemic control: a case-series

2001 ◽  
Vol 16 (3) ◽  
pp. 186-190 ◽  
Author(s):  
K.N. Roy Chengappa ◽  
J. Levine ◽  
D. Rathore ◽  
H. Parepally ◽  
R. Atzert
Keyword(s):  
Glycemic Control ◽  
Type Ii Diabetes ◽  
Case Series ◽  
Mood Stabilizer ◽  
Type Ii Diabetes Mellitus ◽  
Type Ii ◽  
Long Term Effects ◽  
Antiepileptic Agent ◽  
Dsm Iv

SummaryTopiramate is an antiepileptic agent, which is being investigated as a mood-stabilizer. Three obese individuals with DSM-IV bipolar I disorder and type II diabetes mellitus received topiramate treatment in combination with antipsychotics and valproate or carbamazepine. In addition to improved mood stability, these individuals lost between 16 to 20.5% of their pre-topiramate body weight and also achieved significant glycemic control.

Long-Term Effects of Bariatric Surgery on Type II Diabetes, Hypertension and Hyperlipidemia: A Meta-Analysis and Meta-Regression Study with 5-Year Follow-Up

2014 ◽  
Vol 25 (3) ◽  
pp. 397-405 ◽  
Author(s):  
Cristian Ricci ◽  
Maddalena Gaeta ◽  
Emanuele Rausa ◽  
Emanuele Asti ◽  
Francesco Bandera ◽  
...  
Keyword(s):  
Bariatric Surgery ◽  
Type Ii Diabetes ◽  
Meta Analysis ◽  
Type Ii ◽  
Long Term Effects ◽  
Meta Regression

scholarly journals Evaluation of the Relationship between Type II Diabetes Mellitus and the Prevalence of Apical Periodontitis in Root-Filled Teeth Using Cone Beam Computed Tomography: An Observational Cross-Sectional Study

2019 ◽  
Vol 28 (6) ◽  
pp. 533-538
Author(s):  
Selen Nihal Sisli
Keyword(s):  
Diabetes Mellitus ◽  
Computed Tomography ◽  
Glycemic Control ◽  
Cone Beam Computed Tomography ◽  
Type Ii Diabetes ◽  
Type Ii Diabetes Mellitus ◽  
Apical Periodontitis ◽  
Cone Beam ◽  
Control Group ◽  
Type Ii

Objective: This study aimed to investigate the prevalence of apical periodontitis (AP) in patients with type II diabetes mellitus (DM) with either optimal glycemic control (OGC) or poor glycemic control (PGC) compared with nondiabetics using cone beam computed tomography (CBCT). Subjects and Methods: The periapical status of 75 teeth with adequate root canal treatment performed at least 1 year ago that could be visualized in the field of view of CBCT images of 43 DM patients (29 females, 14 males) was compared with a control group consisting of 162 teeth of 86 nondiabetics (56 females, 30 males). In addition, the DM group was divided into subgroups according to the patients’ mean glycated hemoglobin level as either having OGC or PGC. The periapical status of the teeth was evaluated using the CBCT periapical index (CBCTPAI), and AP was diagnosed as a CBCTPAI ≥1. χ2, Fisher’s exact test, and independent-samples t tests were used for the statistical analysis, and p < 0.05 was considered significant. Results: Significant differences between the DM group and the control group were observed (p< 0.05) in terms of AP (the frequencies of both CBCTPAI ≥1 and CBCTPAI ≥3) and the frequency of cardiovascular disease, while there were no significant differences between the DM subgroups (p > 0.05). Conclusion: The prevalence of AP and severe bone destruction in periapical tissues was significantly higher in the DM patients compared with the nondiabetic patients.

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