scholarly journals Cloning and expression of a novel cysteine-rich secreted protein family member expressed in thyroid and pancreatic mesoderm within the chicken embryo

2001 ◽  
Vol 102 (1-2) ◽  
pp. 223-226 ◽  
Author(s):  
Devyn M. Smith ◽  
Lisa A. Collins-Racie ◽  
Valeria A. Marigo ◽  
Drucilla J. Roberts ◽  
Nicole M. Davis ◽  
...  
Keyword(s):  
Family Member ◽  
Chicken Embryo ◽  
Protein Family ◽  
Cloning And Expression ◽  
Secreted Protein

scholarly journals Capped mRNA Degradation Intermediates Accumulate in the Yeast spb8-2 Mutant

1998 ◽  
Vol 18 (9) ◽  
pp. 5062-5072 ◽  
Author(s):  
Ronald Boeck ◽  
Bruno Lapeyre ◽  
Christine E. Brown ◽  
Alan B. Sachs
Keyword(s):  
Saccharomyces Cerevisiae ◽  
Family Member ◽  
Gene Deletion ◽  
Binding Protein ◽  
Mrna Degradation ◽  
Protein Family ◽  
Suppressor Mutation ◽  
Mrna Decapping ◽  
Mrna Species ◽  
Degradation Intermediates

ABSTRACT mRNA in the yeast Saccharomyces cerevisiae is primarily degraded through a pathway that is stimulated by removal of the mRNA cap structure. Here we report that a mutation in the SPB8(YJL124c) gene, initially identified as a suppressor mutation of a poly(A)-binding protein (PAB1) gene deletion, stabilizes the mRNA cap structure. Specifically, we find that thespb8-2 mutation results in the accumulation of capped, poly(A)-deficient mRNAs. The presence of this mutation also allows for the detection of mRNA species trimmed from the 3′ end. These data show that this Sm-like protein family member is involved in the process of mRNA decapping, and they provide an example of 3′-5′ mRNA degradation intermediates in yeast.

scholarly journals The prion protein family member Shadoo induces spontaneous ionic currents in cultured cells

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Antal Nyeste ◽  
Claudia Stincardini ◽  
Petra Bencsura ◽  
Milica Cerovic ◽  
Emiliano Biasini ◽  
...  
Keyword(s):  
Family Member ◽  
Prion Protein ◽  
Cultured Cells ◽  
Ionic Currents ◽  
Protein Family

scholarly journals Expression of the Prion Protein Family Member Shadoo Causes Drug Hypersensitivity That Is Diminished by the Coexpression of the Wild Type Prion Protein

2015 ◽  
Vol 291 (9) ◽  
pp. 4473-4486 ◽  
Author(s):  
Antal Nyeste ◽  
Petra Bencsura ◽  
István Vida ◽  
Zoltán Hegyi ◽  
László Homolya ◽  
...  
Keyword(s):  
Family Member ◽  
Prion Protein ◽  
Drug Hypersensitivity ◽  
Protein Family ◽  
Wild Type

scholarly journals Epl1, the major secreted protein of Hypocrea atroviridis on glucose, is a member of a strongly conserved protein family comprising plant defense response elicitors

FEBS Journal ◽  
2006 ◽  
Vol 273 (18) ◽  
pp. 4346-4359 ◽  
Author(s):  
Verena Seidl ◽  
Martina Marchetti ◽  
Reingard Schandl ◽  
Gunter Allmaier ◽  
Christian P. Kubicek
Keyword(s):  
Plant Defense ◽  
Defense Response ◽  
Protein Family ◽  
Plant Defense Response ◽  
Secreted Protein

scholarly journals Molecular cloning and expression of the cDNA coding for a new member of the S100 protein family from porcine cardiac muscle

FEBS Letters ◽  
1991 ◽  
Vol 295 (1-3) ◽  
pp. 93-96 ◽  
Author(s):  
Hisataka Ohta ◽  
Toshiya Sasaki ◽  
Michiko Naka ◽  
Osamu Hiraoka ◽  
Chikara Miyamoto ◽  
...  
Keyword(s):  
Cardiac Muscle ◽  
Molecular Cloning ◽  
S100 Protein ◽  
Protein Family ◽  
Cloning And Expression

scholarly journals JAM-C Is a Component of Desmosomes and a Ligand for CD11b/CD18-mediated Neutrophil Transepithelial Migration

2004 ◽  
Vol 15 (8) ◽  
pp. 3926-3937 ◽  
Author(s):  
Ke Zen ◽  
Brian A. Babbin ◽  
Yuan Liu ◽  
John B. Whelan ◽  
Asma Nusrat ◽  
...  
Keyword(s):  
Structure Function ◽  
Family Member ◽  
Tight Junctions ◽  
Specific Binding ◽  
Intercellular Junctions ◽  
Protein Family ◽  
Intestinal Epithelia ◽  
Adhesive Interactions

Neutrophil (PMN) transepithelial migration is dependent on the leukocyte β2integrin CD11b/CD18, yet the identity of epithelial counterreceptors remain elusive. Recently, a JAM protein family member termed JAM-C was implicated in leukocyte adhesive interactions; however, its expression in epithelia and role in PMN-epithelial interactions are unknown. Here, we demonstrate that JAM-C is abundantly expressed basolaterally in intestinal epithelia and localizes to desmosomes but not tight junctions. Desmosomal localization of JAM-C was further confirmed by experiments aimed at selective disruption of tight junctions and desmosomes. In assays of PMN transepithelial migration, both JAM-C mAbs and JAM-C/Fc chimeras significantly inhibited the rate of PMN transmigration. Additional experiments revealed specific binding of JAM-C to CD11b/CD18 and provided evidence of other epithelial ligands for CD11b/CD18. These findings represent the first demonstration of direct adhesive interactions between PMN and epithelial intercellular junctions (desmosomes) that regulate PMN transepithelial migration and also suggest that JAM-C may play a role in desmosomal structure/function.

Cloning and expression of the mouse Pse gene encoding a novel Ets family member

Gene ◽  
2000 ◽  
Vol 241 (2) ◽  
pp. 267-274 ◽  
Author(s):  
Naoko Yamada ◽  
Yoshitaka Tamai ◽  
Hiroshi Miyamoto ◽  
Masami Nozaki
Keyword(s):  
Family Member ◽  
Cloning And Expression ◽  
Gene Encoding ◽  
Ets Family
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