1722 Quality of life assessment in Greek breast cancer patients six months after chemotherapy based on an SF-36 questionnaire

The aim of the study was to explore the psychological characteristics and quality of life of patients with cancerous tumor combined with cardiovascular disease. 81 middle-aged patient (51,4±4,6 years) with cancer of different localization examined. Additionally, 42 patients had a concomitant cardiovas- cular pathology. Group of comparison consisted of 39 patients. The following tests and scales were used: test TOBOL for studying the issues of patients’ reaction to desease, Spielberger-Khanin scale to monitor level of anxiety, SF-36 questionnaire to analyze the quality of life. unlike the patients without cardiac pathology, the cancer patients with concomitant cardiovascular pathology showed higher anxi- ety and lower quality of life assessment

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Comparison of the quality of life of women with breast cancer after mastectomy and after breast-conserving therapy: prospective observational study

Journal of Medical Science ◽

10.20883/jms.2017.187 ◽

2017 ◽

Vol 86 (3) ◽

pp. 220

Author(s):

Iwona Głowacka-Mrotek ◽

Magdalena Sowa ◽

Krystyna Nowacka ◽

Tomasz Nowikiewicz ◽

Wojciech Hagner ◽

...

Keyword(s):

Breast Cancer ◽

Quality Of Life ◽

Surgical Treatment ◽

Cancer Patients ◽

Developed Countries ◽

Breast Conserving Therapy ◽

Life Assessment ◽

Breast Cancer Patients ◽

Eortc Qlq

Introduction. Breast cancer is the most common malignancy in women in developed countries. Treatment of this disease affects the quality of life of patients. Quality of life is an ambiguous concept, which refers to the state of health, severity of symptoms, and implemented treatment. It is also linked to meeting individual needs of each person.Aim. The aim of the study was to assess the quality of life of breast cancer patients according to the type of previous surgery.Material and Methods. The study was conducted prospectively. The study population included 101 women with breast cancer after surgical treatment in the period from October 2012 to October 2014 (51 cases after mastectomy, the remaining ones after breast‑conserving therapy). Standard questionnaires EORTC QLQ‑C30 and QLQ‑BR23 were used to assess the quality of life (assessment on the day of admission to the department, two months and one year after surgery).Results. The analysis of QLQ‑C30 revealed no statistically significant differences between the compared groups of patients. Regarding the analysis of QLQ‑BR23, statistically significant differences related to the assessment of the patient's own body and life perspectives, evaluation of sexual feelings and social roles (they were not found in the evaluation of sexual functioning, undesirable effects of treatment or symptoms associated with the affected breast).Conclusions. Regardless of the type of surgery performed, breast cancer patients require similar psychological actions supporting their possibility of adapting to the new situation and dealing with negative effects of surgical treatment.

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A prospective study of quality of life in breast cancer patients undergoing radiation therapy

EURASIAN JOURNAL OF CLINICAL SCIENCES ◽

10.28942/ejcs.v1i1.9 ◽

2017 ◽

Vol 1 (1) ◽

pp. 9

Author(s):

Canhua Xiao ◽

Andrew H. Miller ◽

Mylin A. Torres

Keyword(s):

Breast Cancer ◽

Quality Of Life ◽

Risk Factors ◽

Radiation Therapy ◽

Cancer Patients ◽

Perceived Stress ◽

Breast Cancer Patients ◽

Sf 36 ◽

A Prospective Study

Abstract Purpose: The purpose of this study was to examine the impact of radiation therapy on quality of life (QOL) of breast cancer patients during and until 1 year after radiation therapy treatment. Methods and materials: Thirty-nine breast cancer patients treated with breast-conserving surgery were enrolled in a prospective study before whole breast radiation therapy (50 Gy plus a 10-Gy boost). No patient received chemotherapy. Data were collected before, at week 6 of radiation therapy, and 6 weeks and 1 year after radiation therapy. The primary outcome variable was quality of life (QOL), measured by Medical Outcomes Study 36-Item Short Form Version 2 (SF-36). Risk factors potentially associated with total SF-36 scores and its physical and mental health component summary scores were also examined, including age, race, marital status, smoking history, menopausal status, endocrine treatment, cancer stage, sleep abnormalities (assessed by the Pittsburgh Sleep Quality Index), and perceived stress levels (assessed by the Perceived Stress Scale). Mixed effect modeling was used to observe QOL changes during and after radiation therapy. Results: Total SF-36 scores did not change significantly during and up to 1 year after radiation therapy compared with baseline measures. Nevertheless, increased body mass index (BMI) and increased perceived stress were predictive of reduced total SF-36 scores over time (P Z .0064, and P < .0001, respectively). In addition, increased BMI was predictive of reduced physical component summary scores of the SF-36 (P Z .0011), whereas increased perceived stress was predictive of worse mental component summary scores (P < .0001). Other proposed potential risk factors including skin toxicity from radiation therapy were not significant. Conclusions: Radiation therapy did not worsen QOL in breast cancer patients. However, preradiation therapy patient characteristics including BMI and perceived stress may be used to identify women who may experience decreased physical and mental function during and up to 1 year after radiation therapy. Copyright 2016 the Authors. Published by EJCS on behalf of Uptodate In Medicine LLC Health Sciences Publishing. This is an open access article under the CC BY-NC-ND license (http:// creativecommons.org/licenses/by-nc-nd/4.0/).

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Nutritional Status and Quality of Life in Breast Cancer Patients in Karawaci General Hospital

Indonesian Journal of Cancer ◽

10.33371/ijoc.v10i1.413 ◽

2016 ◽

Vol 10 (1) ◽

pp. 1

Author(s):

ANDREE KURNIAWAN ◽

NATA PRATAMA HARDJO LUGITO

Keyword(s):

Breast Cancer ◽

Quality Of Life ◽

Nutritional Status ◽

Cancer Patients ◽

Physical Functioning ◽

Short Form ◽

Subjective Global Assessment ◽

Breast Cancer Patients ◽

Sf 36

ABSTRACTCancer is related to a deterioration of nutritional status and quality of life (Qol), but the extent of these conditions in patients with breast cancer has not been studied well. Malnutrition is prevalent among cancer patients and maybe correlated with altered quality of life. The aim of this study is to evaluate the association of QoL and nutritional status after breast cancer diagnosed. Nutritional status was evaluated with Patient Generated Subjective Global Assessment and QoL using Short form 36 (SF-36) and also with the specific module for breast cancer patients. A consecutive sampleof twenty two patients diagnosed with breast cancer was evaluated. The associations of QoL with stadium and nutrition status were evaluated using T-test analysis. The mean of body mass index was 21.3 kg/m2. Fifty percent patient have menopause. Most patients were stage II (77.3%), the others stage III (18.2%) and stage I (4.5%). Sixty eight point two percent had risk of malnutrition. The stadium of tumor was significantly related to physical functioning (p < 0.000), physical limitation (p < 0.024), emotional limitation (p < 0.013), well-being (p < 0.020), health changes (p < 0.010). Thestatus of nutrition was significantly related to physical functioning (p < 0.001), loss of energy (p < 0.010) and general health (p <0.005). For Conclusion, the status of nutrition breast cancer patients were related to QoL especially physical functioning, loss of energy and general health after they were diagnosed.ABSTRAKKanker sangat terkait dengan perburukan status nutrisi dan kualitas hidup. Namun demikian, belum banyak studi yang yang melaporkan masalah nutrisi dan kulitas hidup pada kanker payudara. Malnutrisi sering ditemukan pada kanker dan mungkin terkait dengan perubahan kulaitas hidup. Tujuan penelitian ini adalah untuk mengevaluasi hubungan antara kualitas hidup dengan status nutrisi setelah kanker payudara terdiagnosis. Evaluasi status nutrisi dilakukan dengan Patient Generated Subjective Global Assessment dan kualitas hidup dengan Short form 36 (SF-36) sertakarakteristik pada kanker payudara. Sampel diambil dengan teknik konsekutif terhadap 22 pasien yang terdiagnosis kanker payudara. Hubungan kualitas hidup dengan stadium kanker dan status nutrisi dinilai menggunakan analisis T-test. Indeks massa tubuh rata-rata adalah 21,3 kg/m2. Lima puluh pasien telah menopause. Terbanyak adalah stadium 2 (77,3%), stadium 3 (18,2%), dan stadium 1 (4,5%). Enam puluh dua koma dua persen berisiko malnutrisi. Stadium tumor secara bermakna berhubungan dengan fungsi fisik (p <0,000), keterbatasan fisik (p<0,024), keterbatasan emosi(p<0,013), rasa nyaman (p<0,020), dan perubahan kesehatan (p<0,000). Status nutrisi berhubungan secara bermakna dengan fungsi fisik (p<0,001), kehilangan energi (p<0,010), dan kesehatan secara umum (p<0,005). Simpulan, status nutrisi pasien kanker payudara berhubungan dengan kualitas hidup, terutama fungsi fisik, kehilangan energi, status kesehatan umum setelah mereka terdiagnosis.

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ASSESSMENT OF QUALITY OF LIFE IN BREAST CANCER PATIENTS - USING FACT-G, SF-36 AND QLQ-C30 QUESTIONNAIRES

Journal of Medicine and Pharmacy ◽

10.34071/jmp.2011.4.14 ◽

2011 ◽

pp. 98-105

Author(s):

Nguyen Thai Bao Nguyen ◽

Dinh Tung Nguyen ◽

Vu Quoc Huy Nguyen

Keyword(s):

Breast Cancer ◽

Quality Of Life ◽

Cancer Patients ◽

Cancer Staging ◽

Care Quality ◽

Breast Cancer Patients ◽

Cross Sectional ◽

Sf 36 ◽

Quality Of Life Index

Background: The assessment and improvement of Quality of life (QoL) of breast cancer and other diseases patients have been of great concern for a long time. This research is to assessing the QoL of breast cancer patients using the popular and recommended instruments, the FACT-G, SF-36 and QLQ-C30 (including QLQ-BR23). Methods and Materials: A cross-sectional descriptive study on breast cancer patients receiving surgical, chemotherapy and radiotherapy, using FACT-G, SF-36 and QLQ-C30 to evaluate their quality of life. The assessment is mainly based on the patients’ own feelings. Results: Average age: 48.4±13.1. Most patients in the sample are from stage IIA to stage IIIB (TNM Cancer Staging, by AJCC 2010). Quality of life index using FACT-G is 60.6±5.1, using SF-36 is 46.5±11.0 in physical health and 53.1±14.8 in mental health, using QLQ-C30 is 53.1±21.0. Conclusion: The QoL assessment by using these instruments shows results mostly in average on many aspects. The screening needs to be improved for better early-detection and treatment, especially in mental care. Quality of life of breast cancer patients reasearches should be paid more attention and widely expanded.

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Metastatic breast cancer: do current treatments improve quality of life? A prospective study

Sao Paulo Medical Journal ◽

10.1590/s1516-31802006000400006 ◽

2006 ◽

Vol 124 (4) ◽

pp. 203-207 ◽

Cited By ~ 2

Author(s):

Fernanda Amado ◽

Maria Teresa Cruz Lourenço ◽

Daniel Deheinzelin

Keyword(s):

Breast Cancer ◽

Quality Of Life ◽

Metastatic Breast Cancer ◽

Cancer Patients ◽

Short Form ◽

Performance Status ◽

Metastatic Breast ◽

Breast Cancer Patients ◽

Sf 36

CONTEXT AND OBJECTIVE: In metastatic breast cancer cases, the currently available therapeutic approaches provide minimal improvement in survival. As such, quality of life (QOL) becomes one of the main objectives of treatment. It is not known whether current treatments derived from trials improve QOL. The aim was to evaluate changes in QOL among metastatic breast cancer patients receiving treatment derived from trials. DESIGN AND SETTING: Prospective observational QOL survey in a tertiary cancer center. METHODS: To evaluate the influence of current treatments on patients' QOL, the Medical Outcomes Study Short Form-36 (SF-36) and the Beck Depression Inventory (BDI) were applied on three occasions: before starting treatment and at the 6th and 12th weeks, to consecutive metastatic breast cancer patients over a one-year period. RESULTS: We found an improvement in QOL in the sample evaluated (n = 40), expressed by changes in the overall SF-36 score (p = 0.002) and the BDI (p = 0.004). Taken individually, the SF-36 components Pain, Social Functioning and Mental Health also improved significantly. Patients with worse initial performance status and secondary symptoms displayed greater improvement than those with better initial performance status and asymptomatic disease (p < 0.001). Patients who received more than one type of therapy showed larger gains than those given only one type (p = 0.038). CONCLUSIONS: In our environment, current metastatic breast cancer treatments can improve QOL, especially among symptomatic patients and those with low performance status.

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Construct Validity and Reliability of Indonesian Version of RAND SF-36 Quality of Life Questionnaire in Breast Cancer Patients

Indonesian Journal of Cancer ◽

10.33371/ijoc.v13i2.621 ◽

2019 ◽

Vol 13 (2) ◽

pp. 55

Author(s):

Zhafirah Ramadhanty ◽

Kristanto Yuli Yarsa ◽

Ari Probandari

Keyword(s):

Breast Cancer ◽

Quality Of Life ◽

Cancer Patients ◽

Life Questionnaire ◽

Breast Cancer Patients ◽

Validity And Reliability ◽

Community Members ◽

Quality Of Life Questionnaire ◽

Sf 36

Background: The number of breast cancer patients in Indonesia is increasing but there are still only a few researches that assess their quality of life. RAND SF-36 is a quality of life instrument that is widely used. In Indonesia, the validity and reliability of the instrument is still under development, especially in breast cancer patients. Various health status questionnaires have been used in physical rehabilitation studies involving patient with pacemaker, but for women with breast cancer, the usefulness of these questionnaires as measures of physical, mental, and social well-being has not been firmly established. Methods: A previously validated RAND SF-36 questionnaire in patients with pacemaker was given to 252 breast cancer survivor community members. We assessed the construct validity and the reliability by referring to its Pearson’s r table value and Cronbach’s α coefficient. Results: One hundred and fourteen breast cancer survivor community members participated and completed all 36 questions of the instrument between September- November 2018. Questions number 2, 28, and 35 showed lower Pearson’s r value (r<0,300) than other questions but still showed r value of >0.1548 indicating that these questions were valid. Cronbach’s α coefficient >0.90 indicated good internal consistency. Conclusions: The Indonesian version of the SF-36 quality of life questionnaire is a suitable instrument and can be used for research in Indonesian breast cancer patients.

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