The simulation of multiphase flow field in implantable blood pump and analysis of hemolytic capability

2013 ◽  
Vol 25 (4) ◽  
pp. 606-615 ◽  
Author(s):  
Tie-yan Li ◽  
Liang Ye ◽  
Fang-wen Hong ◽  
Deng-cheng Liu ◽  
Hui-min Fan ◽  
...  
Keyword(s):  
Flow Field ◽  
Multiphase Flow ◽  
Blood Pump

scholarly journals Multi-parameter analysis of the effects on hydraulic performance and hemolysis of blood pump splitter blades

2020 ◽  
Vol 12 (5) ◽  
pp. 168781402092129
Author(s):  
Zheqin Yu ◽  
Jianping Tan ◽  
Shuai Wang
Keyword(s):  
Flow Field ◽  
Axial Length ◽  
Axial Flow ◽  
Hydraulic Performance ◽  
Parameter Analysis ◽  
Blood Pump ◽  
Computational Fluid Mechanics ◽  
Structural Improvement ◽  
Axial Flow Blood Pump ◽  
And Performance

The splitter blade can effectively optimize pump performance, but there is still insufficient research in blood pumps that cover both hydraulic and hemolysis performance. Thus, the aim of this study was to investigate the effect of key factors related to splitter blade on the performance and flow field of axial flow blood pump. In this study, the number of splitter blades, the axial length, and the circumferential offset were chosen as three objects of study. An analysis of the flow field and performance of the pump by orthogonal array design using computational fluid mechanics was carried out. A set of hydraulic and particle image velocimetry experiments of the model pumps were performed. The result showed that the pump had greater hydraulic performance without sacrificing its hemolytic performance when it had two splitter blades, the axial length ratio was 0.6, and the circumferential offset was 15°. Based on these reference data, the splitter blade may contribute to greater hydraulic performance of the pump and cause no side effect on the velocity distribution of the flow field. This finding provides an effective method for the research, development, and application of structural improvement of the axial flow blood pump.

Study on the Turbulent Injury Principle of Blood in the High-Speed Spiral Blood Pump

2011 ◽  
Vol 393-395 ◽  
pp. 992-995
Author(s):  
Zhong Yun ◽  
Chuang Xiang ◽  
Xiao Yan Tang ◽  
Fen Shi
Keyword(s):  
Shear Stress ◽  
Flow Field ◽  
Blood Cell ◽  
Turbulent Flow ◽  
Red Blood Cell ◽  
Blood Cells ◽  
High Speed ◽  
Internal Flow ◽  
Blood Pump ◽  
Turbulent Flow Field

The strongly swirling turbulent flow in the internal flow field of a high-speed spiral blood pump(HSBP), is one of important factors leading to the fragmentation of the red blood cell(RBC) and the hemolysis. The study on the turbulent injure principle of blood in the HSBP is carried out by using the theory of waterpower rotated flow field and the hemorheology. The numerical equation of the strongly swirling turbulent flow field is proposed. The largest stable diameter of red blood cells in the turbulent flow field is analyzed. The determinant gist on the red blood cell turbulent fragmentation is obtained. The results indicate that in the HSMP, when turbulent flow is more powerful, shear stress is weaker, the vortex mass with energy in flow field may cause serious turbulent fragmentation because of the diameter which is smaller than the RBC’s. The RBC’s turbulent breakage will occur when the Weber value is larger than 12.

scholarly journals The Research on Optimization of the Multiphase Flow Field of Biogas Plant by Using CFD Software

2014 ◽  
Vol 8 (6) ◽  
Author(s):  
Ruyi Huang ◽  
Yan Long ◽  
Tao Luo ◽  
Zili Mei ◽  
Jun Wang ◽  
...  
Keyword(s):  
Flow Field ◽  
Multiphase Flow ◽  
Biogas Plant

scholarly journals Shear Stress and Hemolysis Analysis of Blood Pump under Constant and Pulsation Speed Based on a Multiscale Coupling Model

2020 ◽  
Vol 2020 ◽  
pp. 1-14
Author(s):  
Shuai Wang ◽  
Jianping Tan ◽  
Zheqin Yu
Keyword(s):  
Shear Stress ◽  
Flow Field ◽  
Coupling Model ◽  
The Body ◽  
Constant Speed ◽  
Blood Pump ◽  
Model Combining ◽  
Speed Change ◽  
Ventricular Motion ◽  
Speed Mode

Current researches show that the constant speed mode adopted by the existing commercial blood pump may cause damage to the body. The way to solve this problem is to produce pulsating flow by changing the speed of the blood pump’s impeller. But at present, the flow field of the blood pump is not clear, when it changes speed, and the coupling between blood pump and body has not been considered in the simulation of the flow field. A multiscale coupling model combining hemodynamics (0D) and Computational Fluid Dynamics (3D) was established in this paper to solve the problem, and a speed change curve consistent with the ventricular motion was selected. The hemodynamics, shear stress, and hemolysis changes of 6000 rpm at different amplitude (2000, 3000, and 4000 rpm) were simulated, analyzed, and compared with the constant speed (7000 rpm). The results show that the pressure difference obtained by simulation is consistent with the experimental results, and the flow generated by the natural heart still flows through the blood pump, thus changing the working point of the blood pump. When the blood pump works at the changing speed, it could produce more pulsation, and the shear stress and hemolysis in the blood pump increase with the rising of speed and flow. But according to the hemolysis score of a single cardiac cycle, the hemolysis value of the changing speed model at an amplitude of 4000 rpm is only 11.71% higher than that of constant speed at 7000 rpm.

Analysis of flow field and hemolysis index in axial flow blood pump by computational fluid dynamics–discrete element method

2020 ◽  
Vol 44 (1) ◽  
pp. 46-54
Author(s):  
Lizhi Cheng ◽  
Jianping Tan ◽  
Zhong Yun ◽  
Shuai Wang ◽  
Zheqin Yu
Keyword(s):  
Fluid Dynamics ◽  
Computational Fluid Dynamics ◽  
Numerical Calculation ◽  
Flow Field ◽  
Discrete Element Method ◽  
Axial Flow ◽  
Discrete Element ◽  
Blood Pump ◽  
Axial Flow Blood Pump ◽  
Element Method

To fully study the relationship between the internal flow field and hemolysis index in an axial flow blood pump, a computational fluid dynamics–discrete element method coupled calculation method was used. Through numerical analysis under conditions of 6000, 8000, and 10,000 r/min, it was found that there was flow separation of blood cell particles in the tip of the impeller and the guide vane behind the impeller. The flow field has a larger pressure gradient distribution, which reduces the lift ratio of the blood pump and easily causes blood cell damage. The study shows that the hemolysis index obtained by the computational fluid dynamics—discrete element method is 4.75% higher than that from the traditional computational fluid dynamics method, which indicates the impact of microcollision between erythrocyte particles and walls on hemolysis index and also further verifies the validity of the computational fluid dynamics–discrete element coupling method. Through the hydraulic and particle image velocimetry experiments of the blood pump, the coincidence between numerical calculation and experiment is analyzed from macro and micro aspects, which shows that the numerical calculation method is feasible.

Structure Design and Flow Field Simulation of Magnetic Liquid Suspension Centrifugal Blood Pump

2014 ◽  
Vol 624 ◽  
pp. 223-227
Author(s):  
Hua Chun Wu ◽  
Zheng Yuan Zhang ◽  
Pu Chen ◽  
Yong Wu Ren
Keyword(s):  
Flow Field ◽  
Magnetic Fluid ◽  
Three Dimensional ◽  
Internal Flow ◽  
Structure Design ◽  
Blood Pump ◽  
Pump Impeller ◽  
Centrifugal Blood Pump ◽  
Pump Design ◽  
Liquid Suspension

To reduce the energy consumption and blood damage of a centrifugal blood pump, this paper uses a permanent magnet bearing and blood flow pressure bearing to support blood pump impeller, design a magnetic fluid suspension centrifugal blood pump, three-dimensional numerical simulation of a magnetic fluid suspension centrifugal blood pump internal flow field, achieve the pressure of the blood pump flow channel and the velocity distribution, get the relationship between blood pressure and flow rate of the pump. The results can provide a theoretical basis for centrifugal blood pump design and improvement.

Computational Prediction of Hemolysis by Blade Flow Field of Micro-Axial Blood Pump

2006 ◽  
Author(s):  
Xin Chen ◽  
Jianping Tan
Keyword(s):  
Blood Flow ◽  
Flow Field ◽  
Fluid Dynamic ◽  
Computational Prediction ◽  
Blood Pump ◽  
Navier Stokes ◽  
Initial Attempt ◽  
Navier Stokes Equation ◽  
Blood Damage ◽  
Blood Pumps

By analyzing fluid dynamics of blood in an artificial blood pump and simulating the flow field structure and the flow performance of blood, the blood flow and the damages in the designed blood pump would be better understood. This paper describes computational fluid dynamic (CFD) used in predicting numerically the hemolysis of blade in micro-axial blood pumps. A numerical hydrodynamical model, based on the Navier-Stokes equation, was used to obtain the flow in a micro-axial blood pump. A time-dependent stress acting on blood particle is solved in this paper to explore the blood flow and damages in the micro-axial blood pump. An initial attempt is also made to predict the blood damage from these simulations.

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