Efficacy and risks of medical therapy for supraventricular tachycardia in neonates and infants

Abstract Introduction: The prevalence of attention deficit/hyperactivity disorder in the general population is common and is now diagnosed in 4%–12% of children. Children with CHD have been shown to be at increased risk for attention deficit/hyperactivity disorder. Case reports have led to concern regarding the use of attention deficit/hyperactivity disorder medications in children with underlying CHD. We hypothesised that medical therapy for patients with CHD and attention deficit/hyperactivity disorder is safe. Methods: A single-centre, retrospective chart review was performed evaluating for adverse events in patients aged 4–21 years with CHD who received attention deficit/hyperactivity disorder therapy over a 5-year span. Inclusion criteria were a diagnosis of CHD and concomitant medical therapy with amphetamines, methylphenidate, or atomoxetine. Patients with trivial or spontaneously resolved CHD were excluded from analysis. Results: In 831 patients with CHD who received stimulants with a mean age of 12.9 years, there was only one adverse cardiovascular event identified. Using sensitivity analysis, our median follow-up time was 686 days and a prevalence rate of 0.21% of adverse events. This episode consisted of increased frequency of supraventricular tachycardia in a patient who had this condition prior to initiation of medical therapy; the condition improved with discontinuation of attention deficit/hyperactivity disorder therapy. Conclusion: The incidence of significant adverse cardiovascular events in our population was similar to the prevalence of supraventricular tachycardia in the general population. Our single-centre experience demonstrated no increased risk in adverse events related to medical therapy for children with attention deficit/hyperactivity disorder and underlying CHD. Further population-based studies are indicated to validate these findings.

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SVT and Gram Negative Sepsis in Neonates

Journal of Nepal Paediatric Society ◽

10.3126/jnps.v39i3.28641 ◽

2019 ◽

Vol 39 (3) ◽

pp. 197-199

Author(s):

Om Krishna Pathak ◽

Yengkhom Rameshwor Singh ◽

Sunil Purswani ◽

Pradeep Suryawanshi

Keyword(s):

Heart Rate ◽

Case Report ◽

Supraventricular Tachycardia ◽

Cardiac Failure ◽

Neonatal Sepsis ◽

Congestive Cardiac Failure ◽

Gram Negative ◽

Neonates And Infants ◽

Culture Positive ◽

Insight Into

Supraventricular tachycardia is the most common tachyarrhythmia seen in fetuses, neonates and infants. Sustained SVT may lead to congestive cardiac failure. Neonatal supraventricular tachycardia is more commonly associated with other cardiorespiratory and congenital problems and is uncommon in an otherwise healthy infant. Supraventricular tachycardia is also caused by neonatal sepsis but has rarely been reported. Here, we report two cases of SVT (Supraventricular tachycardia) induced by neonatal sepsis. Two neonates, one male and another female, both born to Indian mother had tachycardia with heart rate > 220 beats/minute along with poor perfusion, tachypnoea, fever and deranged coagulation profile. Both the babies had culture positive gram negative sepsis with normal echocardiography and supraventricular tachycardia on electrocardiograms which were treated with anti arrhythmic drugs and treatment of sepsis. This case report gives further insight into one more presentation and complication of neonatal sepsis.

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Successful catheter ablation in a newborn with supraventricular tachycardia resistant to medical therapy

Anadolu Kardiyoloji Dergisi/The Anatolian Journal of Cardiology ◽

10.5152/akd.2012.131 ◽

2012 ◽

Cited By ~ 1

Author(s):

Celal Akdeniz ◽

Neslihan Kiplapinar ◽

Fatma Sevinc Sengul ◽

Volkan Tuzcu

Keyword(s):

Catheter Ablation ◽

Supraventricular Tachycardia ◽

Medical Therapy

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Use of a Wire-Directed Microcatheter, without Guiding Catheter or Introducer, to Perform Both Diagnostic and Therapeutic Neuroradiologic Procedures in Neonates and Infants

Rivista di Neuroradiologia ◽

10.1177/197140090201500602 ◽

2002 ◽

Vol 15 (6) ◽

pp. 653-660

Author(s):

G. K. Ricciardi ◽

F. Granata ◽

S. Vinci ◽

A. Biondi ◽

A. Pitrone ◽

...

Keyword(s):

Medical Therapy ◽

Posterior Cranial Fossa ◽

Boston Scientific ◽

Vein Of Galen ◽

Vein Of Galen Malformation ◽

Coated Wire ◽

Diagnostic Angiography ◽

Cranial Fossa ◽

Neonates And Infants ◽

Guiding Catheter

Performing both diagnostic angiography and endovascular treatments in infants and neonates may be a challenge. The choice of materials represents one of the major difficulties. We present two cases of newborns and one of an infant in which an on-the-wire microcatheter with hydrophilic coating was used without any guiding catheter nor sheath in the management of three different pathologies. A 24 gauge cannula, a 0.014-inch micro-guidewire and a hydrophilic-coated wire-directed microcatheter (Tracker Excel 14, Boston Scientific/Target Therapeutics, Freemont, CA, USA) where the only tools used to perform angiographies and subsequent treatments. One of the patients had a rapidly growing facial haemangioma resistant to medical therapy. One had a posterior cranial fossa pial fistula and another had a vein of Galen malformation.

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Hemochromatosis as junctional tachycardia, a rare presentation

Clinics and Practice ◽

10.4081/cp.2017.979 ◽

2017 ◽

Vol 7 (3) ◽

Author(s):

Ali Ghani ◽

Irfan Ahsan ◽

Charles Gottleib

Keyword(s):

Supraventricular Tachycardia ◽

Medical Therapy ◽

Medical Problem ◽

Successful Outcome ◽

Rare Presentation ◽

Junctional Tachycardia

We present here a 45-year-old male with no past medical problem who presented with palpitations. He was found to have supraventricular tachycardia intractable to medical therapy. Later his rhythm converted to junctional tachycardia. Further workup revealed hemochromatosis to be primary etiology causing the arrhythmia. The low index of suspicion for additional workup is key to diagnosis and successful outcome.

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