1.48 Myocardial mass and functional parameters of left-ventricle (LV) measured with gated SPELT: comparison between stress and rest imaging in patients with no perfusion defect

2001 ◽  
Vol 8 (1) ◽  
pp. S12-S12
Author(s):  
B AHN ◽  
J LEE ◽  
S LEE ◽  
K LEE ◽  
H BOM
Author(s):  
S.V. Tretyakov ◽  
◽  
A.A. Popova ◽  

Aim. Study of intramyocardial stress of the left ventricle (LV) in persons exposed to occupational vibration and patients with hand-arm vibration syndrome (HAVS). Materials and methods. We examined 15 individuals exposed to vibration, 44 individuals with grade 1 HAVS, 10 individuals with grade 2. The control group consisted of 20 persons without cardiovascular pathology, who had not been exposed to hazardous occupational factors. The main occupational hazards in persons with HAVS were vibration, noise, physical exertion. Echocardiography was carried out to determine the total volume of LV (Vtotal); the volume of myocardium (Vm); myocardial mass (LVMM); myocardial mass index (LVMMI); systolic intraventricular pressure; the intensity of the functioning of the LV structures; LV circumferential and meridional diastolic and systolic stresses (σcd, σcs and σmd, σms respectively); LV tension in the circumferential and meridional direction during systole and diastole (Tcs, Tcd and Tms, Tmd respectively). Results. In persons exposed to vibration, in comparison with those who have not been exposed to occupational hazards, there is an increase in σmd by 2.5 times (p < 0.05) and σcd by 2.8 times (p < 0.05). The tension increases during systole and diastole both in the circumferential (Tcs by 17.35%, p < 0.05; Tms by 2.74 times, p < 0.05) and in the meridional (Tcd by 14.59%, p < 0.05; Tmd by 2.76 times, p < 0.05) directions. In persons with grade 1 HAVS, there is an increase during diastole σmd by 2.2 times (p < 0.05), σcd by 2.4 times (p < 0.05), and Tmd (p < 0.05) and Tms by 2.5 times (p < 0.05). In patients with grade 2 HAVS, in contrast to those with grade 1 and persons exposed to vibration, there is a change in the working conditions of LV. With the same values of Vtotal, Vm, LVMM and LVMMI, as in the described groups, in patients with grade 2 HAVS, there is a decrease by 12.3% (p < 0.05) in systolic intraventicular pressure against the background of an increase in σmd by 14.7% (p < 0.05), Tmd by 13.6% (p < 0.05), as well as σms by 2.25 times (p < 0.05) and Tcd by 1.97 times (p < 0.05). Conclusion. In the group of persons exposed to vibration and patients with grade 1 HAVS, in contrast to those who are not exposed to occupational hazards, there is an increase in stress and tension, primarily in the circumferential direction during diastole, which indicates the activation of the heterometric type of autoregulation of activity of the heart. In patients with grade 2 HAVS, stress and tension increase in the meridional direction during systole, which indicates the levelling of LV hyperfunction by isotonic type.


2016 ◽  
Vol 68 (3) ◽  
pp. 197-202 ◽  
Author(s):  
Marko Boban ◽  
Alessandro Laviano ◽  
Viktor Persic ◽  
Bojan Biocina ◽  
Mate Petricevic ◽  
...  

Background/Aim: Metabolic derangements due to increased nutritional risk lead to catabolism and loss of proteins, muscle tissue and eventually mass of parenchymatous organs. The aim of our study was to assess whether transitory nutritional risk after heart surgery influences on the left ventricle myocardial mass (LVMM), assessed by echocardiography. Methods: Consecutive sample of patients scheduled for cardiovascular rehabilitation, in period 0-3 months after surgery. Nutritional risk screening (NRS) was analyzed using the NRS-2002 tool. Results: Study sample included 330 patients after heart surgery for ischemic 186 (56.4%); valvular 91 (27.6%) and valvular plus ischemic 53 (16.1%) heart disease. Age was 65.5 ± 10.6 (range 23-84) and there were more male patients than female - 240 (72.7%) and 90 (27.3%), respectively. The percentage of unintentional loss of weight was 10.8 ± 3.4%, in range 0-23.81%, whereas NRS-2002 was 4.4 ± 1.1. LVMM was 218.7 ± 65.9 g vs. 252.3 ± 51.7 (p = 0.015); for patients with increased nutritional risk and controls, respectively. There was no significant correlation of LVMM with NRS-2002, while the percentage of unintentional loss of weight displayed only weakly inverse correlation (Rho CC = -0.197; p = 0.007). LVMM also correlated significantly with body mass index (Rho CC = 0.247; p < 0.001) and waist-to-hip ratio (Rho CC = 0.291; p < 0.001). In conclusion, LVMM was found to decrease slightly in the period of increased nutritional risk, following heart surgery. Changes in LVMM are partially consequences of systemic catabolic response, as well as anthropometric changes due to unintentional loss of weight.


2011 ◽  
Vol 116 (4) ◽  
pp. 505-520 ◽  
Author(s):  
R. Malagò ◽  
D. Tavella ◽  
W. Mantovani ◽  
M. D’Onofrio ◽  
G. Caliari ◽  
...  

1988 ◽  
Vol 77 (3) ◽  
pp. 326-331
Author(s):  
Takao MORI ◽  
Hiroshi YAMABE ◽  
Yoshiyuki YOKOTA ◽  
Kazumi MAEDA ◽  
Hisashi FUKUZAKI

2020 ◽  
Vol 35 (Supplement_3) ◽  
Author(s):  
Aigul Nugmanova ◽  
Nuriya Meriken ◽  
Saule Dikanbayeva ◽  
Zeinep Zhumagulova ◽  
Zhuldyz Baidauletova ◽  
...  

Abstract Background and Aims Pathology of the cardiovascular system is the leading cause of death in patients with CKD, while determining the causes of the formation of cardiac events is often difficult. Method We conducted an analysis of echocardiography data performed by 50 children with CKD. On the echoCG, the final systolic and diastolic sizes of the left ventricle (FSS and FDS), the final systolic and diastolic volumes of the left ventricle (FSV and FDV) were determined; measured the thickness of the interventricular septum (IVS) and the posterior wall of the left ventricle (PWLV). Left ventricular myocardial mass (LVMM) was determined by the formula proposed by R. Devereux and N. Reichek: LVMM = 1.04x (/ IVS+PWLV+FDS/3-FDS3) - 13.6where, IVS - thickness of IVS in diastole,PWLV-thickness of PWLV in diastole, FDS-final diastolic size of the left ventricle. Results We conducted an analysis of echocardiography data performed by 50 children with CKD. On the echoCG, the final systolic and diastolic sizes of the left ventricle (FSS and FDS), the final systolic and diastolic volumes of the left ventricle (FSV and FDV) were determined; measured the thickness of the interventricular septum (IVS) and the posterior wall of the left ventricle (PWLV). Left ventricular myocardial mass (LVMM) was determined by the formula proposed by R. Devereux and N. Reichek: LVMM = 1.04x (/ IVS+PWLV+FDS/3-FDS3) - 13.6where, IVS - thickness of IVS in diastole,PWLV-thickness of PWLV in diastole, FDS-final diastolic size of the left ventricle. Conclusion The mechanisms of damage to the heart and blood vessels in patients with CKD begin to function already in the initial stage of renal failure and increase as it progresses. The need to know the data of clinical, laboratory and instrumental examination methods at the terminal stage of CKD is dictated, first of all, by the possibility of exposure to them. An important stimulus for conducting an echocardiographic examination is the early detection and correction of cardiovascular disorders, in connection with the prospect of increasing the survival of patients after kidney transplantation.


Author(s):  
Semra Ince ◽  
Sait Demirkol ◽  
Alper O. Karacalioglu ◽  
Turgay Celik ◽  
Nuri Arslan

Author(s):  
F. Y. van Driest ◽  
R. J. van der Geest ◽  
A. Broersen ◽  
J. Dijkstra ◽  
M. el Mahdiui ◽  
...  

AbstractCombination of coronary computed tomography angiography (CCTA) and adenosine stress CT myocardial perfusion (CTP) allows for coronary artery lesion assessment as well as myocardial ischemia. However, myocardial ischemia on CTP is nowadays assessed semi-quantitatively by visual analysis. The aim of this study was to fully quantify myocardial ischemia and the subtended myocardial mass on CTP. We included 33 patients referred for a combined CCTA and adenosine stress CTP protocol, with good or excellent imaging quality on CTP. The coronary artery tree was automatically extracted from the CCTA and the relevant coronary artery lesions with a significant stenosis (≥ 50%) were manually defined using dedicated software. Secondly, epicardial and endocardial contours along with CT perfusion deficits were semi-automatically defined in short-axis reformatted images using MASS software. A Voronoi-based segmentation algorithm was used to quantify the subtended myocardial mass, distal from each relevant coronary artery lesion. Perfusion defect and subtended myocardial mass were spatially registered to the CTA. Finally, the subtended myocardial mass per lesion, total subtended myocardial mass and perfusion defect mass (per lesion) were measured. Voronoi-based segmentation was successful in all cases. We assessed a total of 64 relevant coronary artery lesions. Average values for left ventricular mass, total subtended mass and perfusion defect mass were 118, 69 and 7 g respectively. In 19/33 patients (58%) the total perfusion defect mass could be distributed over the relevant coronary artery lesion(s). Quantification of myocardial ischemia and subtended myocardial mass seem feasible at adenosine stress CTP and allows to quantitatively correlate coronary artery lesions to corresponding areas of myocardial hypoperfusion at CCTA and adenosine stress CTP.


2012 ◽  
Vol 93 (3) ◽  
pp. 490-493
Author(s):  
Yu M Belozerov ◽  
Sh M Magomedova ◽  
Z S Abakarova ◽  
I M Osmanov

Aim. To assess the role of subvalvular structures in the development of mitral valve prolapse in children. Methods. Conducted was an echocardiography investigation with comparative analysis of structural and functional parameters of subvalvular structures in healthy children (50 individuals) and children with mitral valve prolapse divided in two groups: first group - without regurgitation (34 children), the second group - with regurgitation (16 children). Results. In healthy children identified were strong correlation links between echocardiographic indices of the subvalvular structures of the mitral valve and the functional parameters of the left ventricle. The diameter of the anterolateral group of papillary muscles directly correlated with the thickness of the interventricular septum, while the diastolic distance between the papillary muscles - with the end diastolic diameter of the left ventricle. It was established that the following factors may contribute to the pathogenesis of mitral valve prolapse: (1) long papillary muscles and the corresponding chords of the valve, (2) a weak (relative to the norm) contractile ability of the papillary muscles, (3) hyperkinesis of the left ventricular apex, and (4) no relationship between the apical and the global ejection fraction. These factors contribute to the fact that the papillary muscles and chords constrain the mitral valve cusps to a lesser extent during systole, which in turn easily bulge into the left atrium under the influence of systolic blood pressure. Apical hyperkinesis contributes to even closer approximation of the subvalvular structures with the cusps. Conclusion. Mitral valve prolapse is attributed to desynchronization of the function of papillary muscles and of the left ventricle; the development of functional mitral regurgitation during mitral valve prolapse is associated with dyssynchrony of the papillary muscles’ activity.


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