P-10 Methylation-Based Expression Loss of Glycophorin C (GYPC) Gene and Clinical Importance in Oral Cancer

Oral Oncology ◽  
2021 ◽  
Vol 118 ◽  
pp. 4
Author(s):  
Metehan Karatas ◽  
Murat Ulusan ◽  
Semra Demokan
2016 ◽  
Vol 8 (1) ◽  
Author(s):  
Cheng-Mei Yang ◽  
Tsung-Han Wang ◽  
Hung-Chih Chen ◽  
Sung-Chou Li ◽  
Ming-Chien Lee ◽  
...  

1990 ◽  
Vol 5 (2) ◽  
pp. 139-144 ◽  
Author(s):  
Bina R. Baxi ◽  
Prabhudas S. Patel ◽  
Siddharth G. Adhvaryu

2020 ◽  
Vol 84 ◽  
pp. S7-S10
Author(s):  
Yu-Hsuan Hsieh ◽  
Chia-Chen Kao ◽  
Cheng-Ta Lin ◽  
Wen-Chung Liu ◽  
Kuo-Chung Yang ◽  
...  

Author(s):  
Karvita B. Ahluwalia ◽  
Nidhi Sharma

It is common knowledge that apparently similar tumors often show different responses to therapy. This experience has generated the idea that histologically similar tumors could have biologically distinct behaviour. The development of effective therapy therefore, has the explicit challenge of understanding biological behaviour of a tumor. The question is which parameters in a tumor could relate to its biological behaviour ? It is now recognised that the development of malignancy requires an alteration in the program of terminal differentiation in addition to aberrant growth control. In this study therefore, ultrastructural markers that relate to defective terminal differentiation and possibly invasive potential of cells have been identified in human oral leukoplakias, erythroleukoplakias and squamous cell carcinomas of the tongue.


2008 ◽  
Vol 17 (2) ◽  
pp. 43-49
Author(s):  
James L. Coyle

Abstract The modern clinician is a research consumer. Rehabilitation of oropharyngeal impairments, and prevention of the adverse outcomes of dysphagia, requires the clinician to select interventions for which evidence of a reasonable likelihood of a successful, important outcome exists. The purpose of this paper is to provide strategies for evaluation of published research regarding treatment of oropharyngeal dysphagia. This article utilizes tutorial and examples to inform and educate practitioners in methods of appraising published research. It provides and encourages the use of methods of efficiently evaluating the validity and clinical importance of published research. Additionally, it discusses the importance of the ethical obligation we, as practitioners, have to use evidence-based treatment selection methods and measurement of patient performance during therapy. The reader is provided with tactics for evaluating treatment studies to establish a study's validity and, thereby, objectively select interventions. The importance of avoiding subjective or unsubstantiated claims and using objective methods of generating empirical clinical evidence is emphasized. The ability to evaluate the quality of research provides clinicians with objective intervention selection as an important, essential component of evidence-based clinical practice. ASHA Code of Ethics (2003): Principle I, Rule F: “Individuals shall fully inform the persons they serve of the nature and possible effects of services rendered and products dispensed…” (p. 2) Principle I, Rule G: “Individuals shall evaluate the effectiveness of services rendered and of products dispensed and shall provide services or dispense products only when benefit can reasonably be expected.” (p. 2) Principle IV, Rule G: “Individuals shall not provide professional services without exercising independent professional judgment, regardless of referral source or prescription.” (p. 4)


2001 ◽  
Vol 120 (5) ◽  
pp. A386-A386
Author(s):  
K HANADA ◽  
F HINO ◽  
H AMANO ◽  
H OOE ◽  
A HIRAMATSU ◽  
...  

2005 ◽  
Vol 173 (4S) ◽  
pp. 177-178
Author(s):  
Heiko Wunderlich ◽  
Alexander Berndt ◽  
Winfried Hindermann ◽  
Kerstin Junker ◽  
Jörg Schubert ◽  
...  

2005 ◽  
Vol 36 (6) ◽  
pp. 7
Author(s):  
Robert Finn
Keyword(s):  

Author(s):  
Chiara Vari ◽  
Patrizia Velotti ◽  
Alessandro Crisi ◽  
Silvana Carlesimo ◽  
Antonio G. Richetta ◽  
...  

Abstract. A broad range of literature reported higher rates of psychopathology and personality disorders among patients affected by skin conditions. Specifically, depression, anxiety, and suicidal ideations are more frequently reported by patients affected by skin diseases. This study aimed to examine psychopathology and personality in a group of patients affected by psoriasis by means of a self-report measure (Millon Clinical Multiaxial Inventory – MCMI-III) and a performance-based technique (Wartegg Drawing Completion Test [WDCT], CWS). Study results showed a higher rate of passive-aggressiveness and paranoia among psoriatic patients (MCMI-III). When assessing patients through the performance-based technique (WDCT, CWS), a higher rate of global rejection (GR) – linked by previous literature to suicidal ideation – and a lower affective quality of the drawings emerged. We discuss the clinical importance of detecting psychological issues in dermatology patients by means of a multimethod assessment that goes beyond patients’ self-evaluation of their symptoms and emotions.


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