Poster 38 - Prospective Case History Study Using Systane™ Lubricant Eye Drops to Help Reduce Symptoms of Dry Eye Associated with Contact Lens Wear

2004 ◽  
Vol 75 (6) ◽  
pp. 372-373
Author(s):  
Stephen Cohen ◽  
William Potter ◽  
Mike Christensen ◽  
Jami R. Kern
2018 ◽  
Vol 6 (5) ◽  
pp. 829-834 ◽  
Author(s):  
Rodiah Rahmawaty Lubis ◽  
Monica Tumiar Hanna Gultom

AIM: To analyze the correlation between the daily lens wear duration and dry eye syndrome.SUBJECTS AND METHODS: This study was an analytic cross sectional study using consecutive sampling conducted among the students in Economy and Bussiness Faculty and Faculty of Humanities in University of Sumatera Utara aged between 17 to 23 that wore contact lens continously for at least a year and 5 days a week. The symptoms were assessed using Contact Lens Dry Eye Questionnaire-8 (CLDEQ-8) and interview about their contact lens comfort; eye drops usage, contact lens washing habit, daily circumstances, places to buy contact lens and personal experince in wearing contact lens.RESULTS: The questionnaire was completed by 53 students. All of them were female and wore softlens wearers. The mean duration of daily wear was 8.19 ± 2.20 hours. The most common symptom experienced was dry eye and the least symptom experienced was removing lens. The most frequent symptom experienced was closing eyes and the least frequent symptom experienced was removing lenses. This study used Exact Test as analysis statistic method. The result was p > 0.05 which means there is no correlation between daily lens wear duration and dry eye syndrome.CONCLUSION: This study showed that dry eye syndrome was not correlated with daily lens wear duration, but affected by many factors such as contact lens, lens care solution, eye drops usage and environment.


2008 ◽  
Vol 85 (8) ◽  
pp. E631-E642 ◽  
Author(s):  
Padmapriya Ramamoorthy ◽  
Jason J. Nichols

2018 ◽  
Vol 1 (1) ◽  
Author(s):  
Hasan Zaidi

Millions of people around the world suffer from dry eye symptoms as a result of extended contact lens wear. The objective of this design document is to engineer a solution for chronic dry eyes. The solution must be safe, effective, easy to use, and affordable. The goal of the treatment is to decrease tear film osmolarity by 20 mOsmol/L. Three types of nanotechnologies were considered for this task. The candidate solutions were 1) hydrogel contact lenses infused with lubricant-loaded liposomes, 2) lubricant-loaded microemulsions applied as eye drops, and 3) lubricant-loaded niosomes applied as eye drops. All solutions use polyethylene glycol 400 as the primary active ingredient in the lubricant. The three solutions provide a safe treatment option that allows increased bioavailability of drug and increased retention time, as well as controlled release of drug. A combination of candidates 1 and 3 – namely, hydrogel contact lenses infused with lubricant-loaded niosomes – seems to be the best solution because of excellent drug delivery kinetics and minimal safety concerns. The success of this project would encourage further research in niosome-based and contact lens-based drug delivery. It would also allow this company to expand research and development and further specialize in ocular drug delivery.


2019 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Karen Molina ◽  
Andrew D. Graham ◽  
Thao Yeh ◽  
Mariel Lerma ◽  
Wing Li ◽  
...  

2016 ◽  
Vol 2016 ◽  
pp. 1-9 ◽  
Author(s):  
Nery García-Porta ◽  
Laura Rico-del-Viejo ◽  
Alba Martin-Gil ◽  
Gonzalo Carracedo ◽  
Jesus Pintor ◽  
...  

Purpose. To compare the ocular surface symptoms and signs in an adult population of silicone-hydrogel (Si-Hy) contact lens (CL) wearers with another modality of CL wear, overnight orthokeratology (OK).Materials and Methods. This was a prospective and comparative study in which 31 myopic subjects were fitted with the same Si-Hy CL and 23 underwent OK treatment for 3 months. Dry eye questionnaire (DEQ) was filled in at the beginning of the study and then after 15 days, 1 month, and 3 months using each CL modality. The tear quality was evaluated with noninvasive tear break-up time. Tear production was measured with Schirmer test. Tear samples were collected with Schirmer strips being frozen to analyze the dinucleotide diadenosine tetraphosphate (Ap4A) concentration with High-Performance Liquid Chromatography (HPLC).Results. After refitting with ortho-k, a reduction in discomfort and dryness symptoms at the end of the day (p<0.05,χ2) was observed. No significant changes were observed in Ap4A concentration in any group. Bulbar redness, limbal redness, and conjunctival staining increased significantly in the Si-Hy group (p<0.05, Kruskal–Wallis test).Conclusion. Discomfort and dryness symptoms at the end of the day are lower in the OK CL group than in the Si-Hy CL group.


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