Abstract #343: Vibration Perception vs Age in Non-diabetic Patients

2006 ◽  
Vol 12 ◽  
pp. 9
Author(s):  
David S. Oyer ◽  
Ajul Shah
Keyword(s):  
Diabetic Patients ◽  
Vibration Perception

scholarly journals The relationship between vibration perception disorder and body sway on type 2 diabetic patients

2017 ◽  
Vol 8 (1) ◽  
pp. 1-5
Author(s):  
Daisuke Iwaki ◽  
Toshihiro Kawae ◽  
Koki Fukuhara ◽  
Yuki Nakashima ◽  
Kenichi Fudeyasu ◽  
...  
Keyword(s):  
Body Sway ◽  
Diabetic Patients ◽  
Type 2 Diabetic Patients ◽  
The Relationship ◽  
Vibration Perception ◽  
Type 2 Diabetic ◽  
Perception Disorder

scholarly journals Fear of Falling Is Prevalent in Older Adults with Diabetes Mellitus But Is Unrelated to Level of Neuropathy

2013 ◽  
Vol 103 (6) ◽  
pp. 480-488 ◽  
Author(s):  
Carolyn Kelly ◽  
Adam Fleischer ◽  
Sai Yalla ◽  
Gurtej S. Grewal ◽  
Rachel Albright ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Older Adults ◽  
Hemoglobin A1c ◽  
Fear Of Falling ◽  
Sensor Technology ◽  
Diabetic Patients ◽  
Perception Threshold ◽  
Vibration Perception Threshold ◽  
Increased Risk ◽  
Vibration Perception

Background: Patients with diabetic peripheral neuropathy (DPN) demonstrate gait alterations compared with their nonneuropathic counterparts, which may place them at increased risk for falling. However, it is uncertain whether patients with DPN also have a greater fear of falling. Methods: A voluntary group of older adults with diabetes was asked to complete a validated fear of falling questionnaire (Falls Efficacy Scale International [FES-I]) and instructed to walk 20 m in their habitual shoes at their habitual speed. Spatiotemporal parameters of gait (eg, stride velocity and gait speed variability) were collected using a validated body-worn sensor technology. Balance during walking was also assessed using sacral motion in the mediolateral and anteroposterior directions. The level of DPN was quantified using vibration perception threshold from the great toe. Results: Thirty-four diabetic patients (mean ± SD: age, 67.6 ± 9.2 years; body mass index, 30.9 ± 5.7; hemoglobin A1c, 7.9% ± 2.3%) with varying levels of neuropathy (mean ± SD vibration perception threshold, 34.6 ± 22.9 V) were recruited. Most participants (28 of 34, 82%) demonstrated moderate to high concern about falling based on their FES-I score. Age (r = 0.6), hemoglobin A1c level (r = 0.39), number of steps required to reach steady-state walking (ie, gait initiation) (r = 0.4), and duration of double support (r = 0.44) were each positively correlated with neuropathy severity (P < .05). Participants with a greater fear of falling also walked with slower stride velocities and shorter stride lengths (r = −0.3 for both, P < .05). However, no correlation was observed between level of DPN and the participant’s actual concern about falling. Conclusions: Fear of falling is prevalent in older adults with diabetes mellitus but is unrelated to level of neuropathy. (J Am Podiatr Med Assoc 103(6): 480–488, 2013)

Screening by Trained Nurses for Peripheral Vascular Disease in Continuous Ambulatory Peritoneal Dialysis Patients with and without Diabetes

2003 ◽  
Vol 23 (2_suppl) ◽  
pp. 134-138 ◽  
Author(s):  
Suk-Yi Ng ◽  
Suk-Wai Cheng ◽  
Wai-Ling Chu ◽  
Sing-Leung Lui ◽  
Wai-Kei Lo
Keyword(s):  
Peritoneal Dialysis ◽  
Vascular Disease ◽  
Peripheral Vascular Disease ◽  
Continuous Ambulatory Peritoneal Dialysis ◽  
Doppler Ultrasound ◽  
Systolic Pressure ◽  
Vascular Complications ◽  
Diabetic Patients ◽  
Peripheral Vascular ◽  
Vibration Perception

Objective We studied the effectiveness of a screening program for peripheral vascular disease (PVD) carried out by trained renal nurses in patients with and without diabetes on continuous ambulatory peritoneal dialysis (CAPD). Patients and Methods We recruited 30 stable diabetic and 30 stable non diabetic CAPD patients into this cross-sectional study. Trained renal nurses measured the patients’ ankle-to-brachial systolic pressure index (ABI) using a Doppler ultrasound machine and their foot vibration perception (VPT) using a biothesiometer, and administered a questionnaire on foot symptoms. An ABI < 1.0 was regarded as abnormal and suggestive of the presence of PVD. An ABI < 0.7 or > 1.3 was regarded as severely abnormal. Findings for VPT were classified as normal or abnormal. Patients were then followed for 1 year for any overt development of clinical PVD, leg complications, and other vascular complications and for clinical outcome. Results The mean age of the patients was 63 ± 9 years, and the ratio of men to women was 1:1.3. An abnormal ABI was seen in 22 patients (37%). The questionnaire detected clinical PVD symptoms in 3 patients. Abnormal ABI and VPT findings were more frequent in diabetic patients. After 12 months of follow-up, patients with an abnormal ABI (and particularly those with a severely abnormal ABI) were more likely to develop leg complications and any type of cardiovascular disease than were patients with a normal ABI. Foot vibration perception had no predictive value on subsequent development of leg complications. When risk factors including age, ABI, and VPT were analyzed by logistic regression, only ABI was a significant independent predictor of subsequent lower-limb vascular complications [odds ratio (OR): 21.0; 95% confidence interval (CI): 2.35 to 187.0; p = 0.00064]. The OR for moderately abnormal ABI was 13.0 (95% CI: 1.015 to 166.3); for severely abnormal ABI, it was 27.4 (95% CI: 2.35 to 187.0, p = 0.0045). Conclusions Measurement of ABI by Doppler ultrasound is a useful and effective screening test for PVD in CAPD patients. In this study, VPT was not shown to be predicative of future leg complications, indicating that peripheral neuropathy plays a less important role in the development of such complications. Our results proved that trained renal nurses can play an active role in detecting foot problems in renal patients by ABI measurement.

Vibration Perception Thresholds in 279 Diabetic Patients

1988 ◽  
Vol 33 (5) ◽  
pp. 334-335 ◽  
Author(s):  
G.M. McKillop ◽  
G.A. Jamal ◽  
C.M. Kesson
Keyword(s):  
Nerve Conduction ◽  
Clinical Evidence ◽  
Early Stage ◽  
Interventional Therapy ◽  
Nerve Conduction Studies ◽  
Diabetic Patients ◽  
Perception Threshold ◽  
Feasible Option ◽  
Nerve Dysfunction ◽  
Vibration Perception

Generalised peripheral neuropathy is a well recognised complication of diabetes mellitus and early detection is important in order that morbidity can be reduced by interventional therapy at an early stage. Since nerve conduction studies are not a feasible option in a busy diabetic clinic, an alternative technique of detection, superior to clinical examination, is beneficial. in this study vibration perception thresholds were measured in 279 diabetic outpatients. Seventy-eight patients (28%) had abnormal results but only 35 (13%) had clinical evidence of neuropathy. While nerve conduction studies remain the most sensitive technique to detect nerve dysfunction, vibration perception threshold determination is a useful screening test to detect subclinical peripheral nerve dysfunction in a routine diabetic outpatient clinic.

Intramuscular Nerve and Neuromuscular Junction Alteration In Extraocular Muscles of Diabetic Mice

1985 ◽  
Vol 43 ◽  
pp. 682-683
Author(s):  
Bruce R. Pachter
Keyword(s):  
Diabetes Mellitus ◽  
Peripheral Nerves ◽  
Sudden Onset ◽  
Extraocular Muscles ◽  
Diabetic Patients ◽  
Oculomotor Palsy ◽  
Third Nerve Palsy ◽  
Patients With Diabetes ◽  
Intramuscular Nerve ◽  
Oculomotor Nerves

Diabetes mellitus is one of the commonest causes of neuropathy. Diabetic neuropathy is a heterogeneous group of neuropathic disorders to which patients with diabetes mellitus are susceptible; more than one kind of neuropathy can frequently occur in the same individual. Abnormalities are also known to occur in nearly every anatomic subdivision of the eye in diabetic patients. Oculomotor palsy appears to be common in diabetes mellitus for their occurrence in isolation to suggest diabetes. Nerves to the external ocular muscles are most commonly affected, particularly the oculomotor or third cranial nerve. The third nerve palsy of diabetes is characteristic, being of sudden onset, accompanied by orbital and retro-orbital pain, often associated with complete involvement of the external ocular muscles innervated by the nerve. While the human and experimental animal literature is replete with studies on the peripheral nerves in diabetes mellitus, there is but a paucity of reported studies dealing with the oculomotor nerves and their associated extraocular muscles (EOMs).

A Comparison Between Sterological Point Counting and Digitizing Tablets

1985 ◽  
Vol 43 ◽  
pp. 666-667
Author(s):  
John M. Basgen ◽  
Eileen N. Ellis ◽  
S. Michael Mauer ◽  
Michael W. Steffes
Keyword(s):  
Electron Microscopy ◽  
Kidney Tissue ◽  
Volume Density ◽  
Diabetic Patients ◽  
Normal Kidney ◽  
Point Counting ◽  
Normal Kidney Tissue ◽  
Biopsy Specimens ◽  
Mitochondrial Volume ◽  
Kidney Lesions

To determine the efficiency of methods of quantitation of the volume density of components within kidney biopsies, techniques involving a semi-automatic digitizing tablet and stereological point counting were compared.Volume density (Vv) is a parameter reflecting the volume of a component to the volume that contains the component, e.g., the fraction of cell volume that is made up of mitochondrial volume. The units of Vv are μm3 /μm3.Kidney biopsies from 15 patients were used. Five were donor biopsies performed at the time of kidney transplantation (patients 1-5, TABLE 1) and were considered normal kidney tissue. The remaining biopsies were obtained from diabetic patients with a spectrum of diabetic kidney lesions. The biopsy specimens were fixed and embedded according to routine electron microscogy protocols. Three glomeruli from each patient were selected randomly for electron microscopy. An average of 12 unbiased and systematic micrographs were obtained from each glomerulus and printed at a final magnification of x18,000.

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