Th-W58:3 Cardiovascular risk factors in childhood and carotid artery intima-media thickness in adulthood: The childhood determinants of adult health study

2006 ◽  
Vol 7 (3) ◽  
pp. 483-484
Author(s):  
C.G. Magnussen ◽  
A. Venn ◽  
T. Dwyer ◽  
O.T. Raitakari
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Carotid Artery ◽  
Cardiovascular Risk Factors ◽  
Intima Media Thickness ◽  
Health Study ◽  
Adult Health ◽  
Media Thickness

The Effects of an Intensive Lifestyle Modification Program on Carotid Artery Intima-Media Thickness: A Randomized Trial

2007 ◽  
Vol 21 (6) ◽  
pp. 510-516 ◽  
Author(s):  
Steven G. Aldana ◽  
Roger Greenlaw ◽  
Audrey Salberg ◽  
Ray M. Merrill ◽  
Ron Hager ◽  
...  
Keyword(s):  
Risk Factors ◽  
Heart Disease ◽  
Cardiovascular Risk ◽  
Carotid Artery ◽  
Cardiac Rehabilitation ◽  
Cardiovascular Risk Factors ◽  
Dietary Habits ◽  
Intima Media Thickness ◽  
Media Thickness ◽  
Number Of Patients

Purpose. This study evaluated the effect of the Dr. Dean Ornish Program for Reversing Heart Disease on cardiovascular disease as measured by the intima-media thickness of the common carotid artery and compared this effect to outcomes from patients participating in traditional cardiac rehabilitation. Design. Randomized clinical trial. Setting. SwedishAmerican Health System. Subjects. Ninety three patients with clinically confirmed coronary artery disease were randomly assigned to the intervention (n = 46) or traditional cardiac rehabilitation (n = 47). Intervention. Dr. Dean Ornish Program for Reversing Heart Disease. Measures. Ultrasound of the carotid artery and other cardiovascular risk factors were measured at baseline, 6, and 12 months. Analysis. Intent-to-treat analysis. Results. There was no significant reduction in the carotid intima-media thickness of the carotid artery in the Ornish group or the cardiac rehabilitation group. Ornish Program participants had significantly improved dietary habits (p < .001), weight (p < .001), and body mass index (p < .001) as compared with the rehabilitation group. The decrease in the number of patients with angina from baseline to 12 months was 44% in Ornish and 12% in cardiac rehabilitation. Conclusions. The Ornish Program appears to causes improvements in cardiovascular risk factors but does not appear to change the atherosclerotic process as it affects the carotid artery.

Association Between Carotid Artery Intima-Media Thickness and Cardiovascular Risk Factors in CKD

2005 ◽  
Vol 46 (5) ◽  
pp. 856-862 ◽  
Author(s):  
Emma Preston ◽  
Mary R. Ellis ◽  
Elena Kulinskaya ◽  
Alun H. Davies ◽  
Edwina A. Brown
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Carotid Artery ◽  
Cardiovascular Risk Factors ◽  
Intima Media Thickness ◽  
Media Thickness

scholarly journals Sex modifies the association between body mass index and carotid artery intima media thickness in the multi-ethnic Singapore population

2021 ◽  
Vol 42 (Supplement_1) ◽  
Author(s):  
R Dalan ◽  
T Mina ◽  
N A Nur Azizah ◽  
T Tong ◽  
M Loh ◽  
...  
Keyword(s):  
Risk Factors ◽  
Body Mass Index ◽  
Cardiovascular Risk ◽  
Carotid Artery ◽  
Cardiovascular Risk Factors ◽  
Body Mass ◽  
Intima Media Thickness ◽  
Cvd Risk ◽  
Media Thickness ◽  
Healthy Participants

Abstract Background and aims Globally cardiovascular disease (CVD) risk is higher in men than in women in the younger age group but the risk is attenuated in later life with an unexpected higher risk in women in some populations. A better understanding of sex differences in CVD is needed. Carotid artery intima-media thickness (CIMT) has been proposed for CVD risk assessment in individuals at intermediate risk. We study the gender interactions in the associations of the traditional cardiovascular risk factors with CIMT. Methods We performed carotid ultrasonography in the large population health study-HELIOS conducted in Singapore. Measurements were performed as per Mannheim consensus, at the far wall of bilateral common carotid artery at 8 sites in each participant. We report the average of all measurements (avgCIMT) and maximum value (maxCIMT). We analysed 2061 healthy participants recruited between 2018–2020. Inclusion criteria for this analysis: non-smokers, not known to have diabetes, hypertension, hyperlipidemia or ischemic heart disease. Individuals with systolic blood pressure &gt;160 mm Hg or fasting glucose &gt;7.0 mmol/L on recruitment were excluded. Multivariable linear regression analysis was performed to examine the association between CIMT and cardiovascular risk factors in the healthy population adjusting for age, sex and ethnicity. All analysis was performed using Stata version 16.0. Results After exclusion, 1407 healthy participants were included in the analysis. Median (IQR) avgCIMT: 0.56 (0.50, 0.65) in men; 0.54 (0.50, 0.58) in women. Median (IQR) maxCIMT: 0.64 (0.57, 0.76) in men; 0.61 (0.54, 0.70) in women. The avgCIMT and the maxCIMT were higher in males when compared to women and all traditional cardiovascular risk factors associated with CIMT after adjustment for age, sex and ethnicity (P&lt;0.05) (Table 1). Interaction tests in multivariable model adjusted for age, ethnicity, pulse pressure, non HDL-C and HbA1c showed a significant interaction between sex and body mass index (BMI) with predicted effects on avgCIMT and maxCIMT being relatively higher in males at the same BMI when compared to females (P-interaction &lt;0.01) (Figure 1). Conclusion Sex modifies the relationship between BMI and CIMT in Singapore's multi-ethnic population. Understanding the intermediary mechanisms involved will help in developing personalized preventive strategies. FUNDunding Acknowledgement Type of funding sources: None. Figure 1

scholarly journals Cardiovascular Risk Factors in Childhood and Carotid Artery Intima-Media Thickness in Adulthood

JAMA ◽  
2003 ◽  
Vol 290 (17) ◽  
pp. 2277 ◽  
Author(s):  
Olli T. Raitakari ◽  
Markus Juonala ◽  
Mika Kähönen ◽  
Leena Taittonen ◽  
Tomi Laitinen ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Carotid Artery ◽  
Cardiovascular Risk Factors ◽  
Intima Media Thickness ◽  
Media Thickness

scholarly journals Carotid artery intima media thickness in obese children : relation with cardiovascular risk factors

2007 ◽  
Vol 50 (11) ◽  
pp. 1091
Author(s):  
Jin Lee ◽  
Hyo Jin Kwon ◽  
Moon Ho Park ◽  
Ki Young Jang ◽  
Kee-Hyoung Lee ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Carotid Artery ◽  
Cardiovascular Risk Factors ◽  
Intima Media Thickness ◽  
Obese Children ◽  
Media Thickness

scholarly journals Circulating Estradiol Is an Independent Predictor of Progression of Carotid Artery Intima-Media Thickness in Middle-Aged Men

2006 ◽  
Vol 91 (11) ◽  
pp. 4433-4437 ◽  
Author(s):  
Åsa Tivesten ◽  
Johannes Hulthe ◽  
Karin Wallenfeldt ◽  
John Wikstrand ◽  
Claes Ohlsson ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Carotid Artery ◽  
Cardiovascular Risk Factors ◽  
Density Lipoprotein ◽  
Intima Media Thickness ◽  
Middle Aged ◽  
Media Thickness ◽  
Cardiovascular Morbidity And Mortality

Abstract Context: Estrogen treatment of men with prostate cancer is associated with increased cardiovascular morbidity and mortality; however, the role of endogenous estrogen levels for atherosclerotic disease in men is unknown. Objective: The objective of the study was to determine whether endogenous serum estradiol (E2) levels predict the progression of carotid artery intima-media thickness in men. Design, Setting and Participants: This was a population-based, prospective cohort study (the Atherosclerosis and Insulin Resistance study) conducted in Göteborg, Sweden, among 313 Caucasian men without cardiovascular or other clinically overt diseases. Carotid artery intima-media thickness, an index of preclinical atherosclerosis, was measured by ultrasound at baseline (58 yr of age) and after 3 yr of follow-up. Serum sex hormone levels and cardiovascular risk factors (body mass index, waist to hip ratio, systolic blood pressure, serum triglycerides, plasma c-peptide, and smoking status) were assessed at study entry. Intervention: There was no intervention. Main Outcome Measures: Association between baseline total and free E2 levels and progression of carotid intima-media thickness over 3 yr with adjustments for cardiovascular risk factors was measured. Results: In univariate analyses, both total and free E2 levels at baseline were positively associated with the annual change in intima-media thickness. In linear regression models including E2 and cardiovascular risk factors, low-density lipoprotein and high-density lipoprotein cholesterol and E2 were identified as independent predictors of progression of carotid artery intima-media thickness (total E2 beta = 0.187, P = 0.001; and free E2 beta = 0.183, P = 0.003). Conclusions: Circulating E2 is a predictor of progression of carotid artery intima-media thickness in middle-aged men. Further studies are needed to investigate the role of endogenous E2 for incident cardiovascular disease events.

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