scholarly journals Analysis of hyaluronic acid concentration in rat vocal folds during estral and gravidic puerperal cycles

2009 ◽  
Vol 75 (5) ◽  
pp. 654-659
Author(s):  
José Eduardo de Sá Pedroso ◽  
Osíris Camponês do Brasil ◽  
João Roberto Maciel Martins ◽  
Helena Bociane Nader ◽  
Manuel de Jesus Simões
Keyword(s):  
Hyaluronic Acid ◽  
Acid Concentration ◽  
Vocal Folds

scholarly journals Analysis of hyaluronic acid concentration in rat vocal folds during estral and gravidic puerperal cycles

2009 ◽  
Vol 75 (5) ◽  
pp. 654-659 ◽  
Author(s):  
José Eduardo de Sá Pedroso ◽  
Osíris Camponês do Brasil ◽  
João Roberto Maciel Martins ◽  
Helena Bociane Nader ◽  
Manuel de Jesus Simões
Keyword(s):  
Hyaluronic Acid ◽  
Acid Concentration ◽  
Vocal Folds

Histologic Characterization of Rat Vocal Fold Scarring

2005 ◽  
Vol 114 (3) ◽  
pp. 183-191 ◽  
Author(s):  
Tomoko Tateya ◽  
Jin Ho Sohn ◽  
Ichiro Tateya ◽  
Diane M. Bless
Keyword(s):  
Hyaluronic Acid ◽  
Vocal Fold ◽  
Type I Collagen ◽  
Collagen Type ◽  
Control Level ◽  
Vocal Folds ◽  
Collagen Type I ◽  
Type I ◽  
Type Iii ◽  
Blue Stain

This study aimed to clarify the characteristics of rat vocal fold scarring by examining the alteration of key components in the extracellular matrix: hyaluronic acid, collagen, and fibronectin. Under monitoring with a 1.9-mm-diameter telescope, unilateral vocal fold stripping was performed, and larynges were harvested at 2, 4, 8, and 12 weeks after operation. The vocal folds were histologically analyzed with Alcian blue stain, trichrome stain, and immunofluorescence of collagen type I, collagen type III, and fibronectin. The scarred vocal folds showed less hyaluronic acid and more collagen types I and III than did the controls at all time points. Type III was stable for 12 weeks, while type I declined until 8 weeks and thereafter remained unchanged. Fibronectin increased for 4 weeks and then decreased; it was close to the control level at 8 and 12 weeks. These results suggest that the tissue remodeling process in scarred vocal folds slows down around 2 months after wounding.

Hyaluronic acid filler vascular complication management: an updated and easy-to-follow emergency protocol

2021 ◽  
Vol 10 (Sup1) ◽  
pp. 34-38
Author(s):  
Erick Santaella-Sosa
Keyword(s):  
Hyaluronic Acid ◽  
Acid Concentration ◽  
Current Literature ◽  
Vascular Complication ◽  
Complication Management ◽  
Biophysical Properties ◽  
Product Characteristics ◽  
Physiochemical Properties ◽  
Molecular Weights

With the breadth and variety of hyaluronic acid hydrogels available, it can be challenging to understand the evolving product characteristics and associated terminology. Similarly, different hyaluronic acid hydrogels can share the same indication, and yet consist of different rheological and physiochemical properties. In this paper, hyaluronic acid biophysical properties, such as molecular weights, stabilisation (crosslinking), modification and hyaluronic acid concentration, are explored in relation to findings from current literature. The significance for these specific properties is explored in relation to specific indications and anti-ageing benefits.

In vitro synthesis of glycosaminoglycans in endocrine ophthalmopathy

1992 ◽  
Vol 127 (5) ◽  
pp. 397-402 ◽  
Author(s):  
G Kahaly ◽  
C Stover ◽  
J Beyer ◽  
E Otto
Keyword(s):  
Hyaluronic Acid ◽  
Acid Concentration ◽  
Cetylpyridinium Chloride ◽  
Acid Synthesis ◽  
Cell Mediated Immunity ◽  
Glycosaminoglycan Synthesis ◽  
In Vitro Synthesis ◽  
Significant Difference ◽  
Endocrine Ophthalmopathy

The effects of humoral and cell-mediated immunity on the glycosaminoglycan synthesis of retrobulbar fibroblasts was evaluated in patients with endocrine ophthalmopathy. After incubation with IgG and sera, secreted glycosaminoglycans, radiolabeled with D-6-3H-glucosamine and 35sulfate, were precipitated with cetylpyridinium chloride and ethanol. Hyaluronic acid synthesis of human retrobulbar fibroblasts after incubation with sera and IgG and after co-culture with lymphocytes was assessed by means of a radiometric test. Patients' IgG, compared to controls', accounted for a higher secretory stimulation of porcine retrobulbar fibroblasts (as measured by cetylpyridinium chloride precipitation) after 24 and 48 h. Contrasting with 24 h incubation time, glycosaminoglycan values after 48 h were increased two to threefold. Patients' and controls' sera caused earlier and stronger, yet indistinguishable glycosaminoglycan production. Non-sulfated hyaluronic acid was the preponderant glycosaminoglycan secreted into the media by retrobulbar fibroblasts. As assessed with the radiometric test, incubation with patients' and controls' sera and IgG did not reveal a significant difference in stimulating the hyaluronic synthesis of patients' and controls' retrobulbar fibroblasts. When measuring the hyaluronic acid synthesis of controls' and patients' retrobulbar fibroblasts after co-cultivation of lymphocytes, however, patients' lymphocytes had a marked ability to increase the hyaluronic acid concentration compared to controls' lymphocytes. The hyaluronic acid concentration after incubation of a patient's retrobulbar fibroblasts with autologous lymphocytes was markedly more elevated than the intrinsic hyaluronic acid production of retrobulbar fibroblasts. In conclusion, though a significant in vitro influence of patients' IgG and sera on the glycosaminoglycan release of both porcine and human (patients' as well as controls') retrobulbar fibroblasts could not be observed in this study, the indications of a marked stimulatory influence of lymphocytes on the hyaluronic acid secretion of retrobulbar fibroblasts demand further investigation.

Hyaluronic acid concentration of diabetic rats’ vaginas treated with soybean isoflavones or 17β-estradiol

Maturitas ◽  
2015 ◽  
Vol 82 (3) ◽  
pp. 318
Author(s):  
A.A.F. Carbonel ◽  
C.R.A. Bertoncini ◽  
V.C. do Amaral ◽  
P.L. da Silva ◽  
R.S. Simoes
Keyword(s):  
Hyaluronic Acid ◽  
Acid Concentration ◽  
Diabetic Rats ◽  
Soybean Isoflavones ◽  
17Β Estradiol

THE CONCENTRATION AND SYNTHESIS OF GLYCOSAMINOGLYCANS IN THE SKIN AND TRACHEAL CARTILAGE OF NORMAL AND ORCHIDECTOMIZED RATS INJECTED WITH TESTOSTERONE

1970 ◽  
Vol 63 (2) ◽  
pp. 193-198 ◽  
Author(s):  
J. A. Kofoed ◽  
C. E. Bozzini ◽  
A. A. Tocci
Keyword(s):  
Hyaluronic Acid ◽  
Acid Concentration ◽  
Specific Effect ◽  
Tracheal Cartilage ◽  
Acidic Glycosaminoglycans

ABSTRACT Normal and orchidectomized rats were injected on alternate days with 10 mg of testosterone for 20 days in order to study the effect of the hormone on both the distribution and the rate of synthesis of glycosaminoglycans in the skin and tracheal cartilage. Testosterone exerts a very specific effect on the acidic glycosaminoglycans by increasing the hyaluronic acid concentration more than twice. The sulphated fractions do not appear to be affected. The above increase in probably due to an augmentation of synthesis of hyaluronate, as evidenced by an increased uptake of 14C acetate by this fraction.

Preservation of Viscoelastic Properties of Rabbit Vocal Folds after Implantation of Hyaluronic Acid-Based Biomaterials

2012 ◽  
Vol 147 (3) ◽  
pp. 515-521 ◽  
Author(s):  
Jeong-Seok Choi ◽  
Nahn Ju Kim ◽  
Sarah Klemuk ◽  
Yun Ho Jang ◽  
In Suh Park ◽  
...  
Keyword(s):  
Hyaluronic Acid ◽  
Viscoelastic Properties ◽  
Vocal Folds

scholarly journals Рівень гіалуронату та загальної гіалуронат-зв’язувальної активності білків за умов розвитку експериментального хронічного гепатиту С та лікування альфа-кетоглутаратом

2010 ◽  
Vol 1 (2) ◽  
pp. 85-89
Author(s):  
O. Z. Fomenko ◽  
G. A. Ushakova ◽  
S. G. Pierzynowski
Keyword(s):  
Chronic Hepatitis ◽  
Hyaluronic Acid ◽  
Hepatitis C ◽  
Blood Serum ◽  
Chronic Hepatitis C ◽  
Acid Concentration ◽  
Normal Condition ◽  
Binding Activity ◽  
Experimental Chronic Hepatitis ◽  
The Absolute

The increase of hyaluronic acid concentration in the blood serum of rats during modelling of chronic hepatitis C is presented. The research of changes in the absolute and relative hyaluronate-binding activity of cytosolic proteins in the rats’ cerebellum and hippocampus under normal condition, experimental chronic hepatitis C and with the alfa-ketoglutarate treatment was carried out.

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