P-182 The Impact of Linear Ablations on the Functional Properties of Left Atrium in Patients with Paroxysmal Atrial Fibrillation

2009 ◽  
Vol 4 ◽  
pp. S103
Author(s):  
Hsuan-Ming Tsao ◽  
Wei-Chih Hu ◽  
Mei-Han Wu ◽  
Shih-Ann Chen
Keyword(s):  
Atrial Fibrillation ◽  
Left Atrium ◽  
Functional Properties ◽  
Paroxysmal Atrial Fibrillation ◽  
The Impact

Changes of QT interval in the acute phase after pulmonary vein isolation for paroxysmal atrial fibrillation

2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
A Chikata ◽  
T Kato ◽  
K Ududa ◽  
S Fujita ◽  
K Otowa ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Pulmonary Vein ◽  
Female Patient ◽  
Pulmonary Vein Isolation ◽  
Acute Phase ◽  
Paroxysmal Atrial Fibrillation ◽  
Qt Interval ◽  
Qt Prolongation ◽  
Qtc Interval ◽  
The Impact

Abstract Introduction Pulmonary vein isolation (PVI) affects ganglionated plexi (GP) around the atrium, leading to a modification of the intrinsic cardiac autonomic system (ANS). In animal models, GP ablation has a potential risk of QT prolongation and ventricular arrhythmias. However, the impact of PVI on QT intervals in humans remains unclear. Purpose This study aims to evaluate the Impact of PVI on QT interval in patients with paroxysmal atrial fibrillation. Methods We analyzed consecutive 117 PAF patients for their first PVI procedures. 12-lead ECG was evaluated at baseline, 4 hr, day 1, 1 month, and 3 months after ablation. Only patients with sinus rhythm on 12-lead ECG at each evaluation point without antiarrhythmic drugs were included. Results Heart rate significantly increased at 4 hr, day 1, and 1 month. Raw QT interval prolonged at 4 hr (417.1±41.6 ms, P<0.001) but shortened at day 1 (376.4±34.1 ms, P<0.001), 1 month (382.2±31.5 ms, P<0.001), and 3 months (385.1±32.8 ms, P<0.001) compared to baseline (391.6±31.4 ms). Bazett- and Fridericia- corrected QTc intervals significantly prolonged at 4hr (Bazett: 430.8±27.9 ms, P<0.001; Fridericia: 425.8±27.4 ms, P<0.001), day1 (Bazett: 434.8±22.3 ms, P<0.001; Fridericia: 414.1±23.7 ms, P<0.001), 1M (Bazett: 434.8±22.3 ms, P<0.001; Fridericia: 408.2±21.0 ms, P<0.05), and 3M (Bazett: 420.1±21.8 ms, P<0.001; Fridericia: 407.8±21.1 ms, P<0.05) compared to baseline (Bazett: 404.9±25.2 ms; Fridericia: 400.0±22.6 ms). On the other hand, Framingham- and Hodges- corrected QTc interval significantly prolonged only at 4hr (Framingham: 424.1±26.6 ms, P<0.001; Hodges: 426.8±28.4 ms, P<0.001) and at day1 (Framingham: 412.3±29.3 ms, P<0.01; Hodges: 410.6±40.2 ms, P<0.05) compared to baseline (Framingham: 399.2±22.7 ms; Hodges: 400.7±22.8 ms). At 4 hr after ablation, raw QT and QTc of all formulas significantly prolonged than baseline. Raw QT and QTc prolongation at 4hr after ablation were more frequently observed in female patients. Multiple regression analysis revealed that female patient is a significant predictor of raw QT and QTc interval prolongation of all formulas 4hr after PVI. Conclusions Raw QT and QTc prolonged after PVI, especially in the acute phase. Female patient is a risk factor for QT prolongation in the acute phase after PVI. Funding Acknowledgement Type of funding source: None

P1415Wide antral circumferential pulmonary vein isolation ablation using a novel balloon cryoablation catheter

EP Europace ◽  
2020 ◽  
Vol 22 (Supplement_1) ◽  
Author(s):  
A P Martin ◽  
M Fowler ◽  
N Lever
Keyword(s):  
Atrial Fibrillation ◽  
Left Atrium ◽  
Pulmonary Vein ◽  
Pulmonary Vein Isolation ◽  
Paroxysmal Atrial Fibrillation ◽  
Left Atrial ◽  
Pulmonary Veins ◽  
Posterior Wall ◽  
The Novel ◽  
Median Treatment

Abstract Background Pulmonary vein isolation using cryotherapy is an established treatment for the management of patients with paroxysmal atrial fibrillation. Ablation using the commercially available balloon cryocatheter has been shown to create wide antral pulmonary vein isolation. A novel balloon cryocatheter (BCC) has been designed to maintain uniform pressure and size during ablation, potentially improving contact with the antral anatomy. The extent of ablation created using the novel BCC has not previously been established. Purpose To determine the anatomical extent of pulmonary vein isolation using electroanatomical mapping when performing catheter ablation for paroxysmal atrial fibrillation using the novel BCC. Methods Nine consecutive patients underwent pre-procedure computed tomography angiography of the left atrium to quantify the chamber dimensions. An electroanatomical map was created using the cryoablation system mapping catheter and a high definition mapping system. A bipolar voltage map was obtained following ablation to determine the extent of pulmonary vein isolation ablation. A volumetric technique was used to quantify the extent of vein and posterior wall electrical isolation in addition to traditional techniques for proving entrance and exit block. Results All patients had paroxysmal atrial fibrillation, mean age 56 years, 7 (78%) male. Electrical isolation was achieved for 100% of the pulmonary veins; mean total procedure time was 109 min (+/- 26 SD), and fluoroscopy time 14.9 min (+/- 2.4 SD). The median treatment applications per vein was one (range one - four), and median treatment duration 180 sec (range 180 -240). Left atrial volume 32 mL/m2 (+/- 7 SD), and mean left atrial posterior wall area 22 cm2 (+/- 4 SD). Data was available for quantitative assessment of the extent of ablation for eight patients. No lesions (0 of 32) were ostial in nature. The antral surface area of ablation was not statistically different between the left and right sided pulmonary veins (p 0.63), which were 5.9 (1.6 SD) and 5.4 (2.1 SD) cm2 respectively. In total 50% of the posterior left atrial wall was ablated.  Conclusion Pulmonary vein isolation using a novel BCC provides a wide and antral lesion set. There is significant debulking of the posterior wall of the left atrium. Abstract Figure.

scholarly journals The effects of different preventive counseling programs on stress level in patients with paroxysmal atrial fibrillation after catheter ablation

2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
N Pogosova ◽  
Y.M Yufereva ◽  
A.I Ovchinnikova ◽  
O.Y Sokolova ◽  
K.V Davtyan
Keyword(s):  
Atrial Fibrillation ◽  
Catheter Ablation ◽  
Stress Level ◽  
Paroxysmal Atrial Fibrillation ◽  
Stressful Life Events ◽  
Controlled Study ◽  
Counseling Programs ◽  
Preventive Counseling ◽  
Group 2 ◽  
The Impact

Abstract Background Stressful life events may trigger paroxysmal atrial fibrillation (AF) and chronic stress is known to negatively affect long-term outcomes in cardiovascular diseases. Purpose To assess the impact of different preventive counseling programs on stress level in patients (pts) after catheter ablation (CA) performed for paroxysmal AF. Methods This is a prospective randomized controlled study with 3 parallel groups of pts with paroxysmal AF after CA (radiofrequency or cryoablation). Pts were randomized into 3 groups in 1:1:1 ratio. During hospitalization for CA pts from all groups received single-session preventive counseling with focus on their individual cardiovascular risk factors profile. After discharge pts from Group 1 received remote preventive counseling by phone and pts from Group 2 by email every two weeks for the first 3 months after enrollment (a total of 6 sessions). Group 3 received usual care. All pts underwent stress assessment using a 10-point visual analogue scale (VAS) at baseline and at 12 months after CA. Results A total of 135 pts aged 35 to 80 years were enrolled (mean age 57.3±9.1 years, 51.8% men). The groups were well balanced according to demographic and clinical features. At 1 year of follow-up there was a significant reduction of average stress level in both intervention groups vs. control (Table). Conclusions Preventive counseling followed by 3 months of remote support via phone and email reduced the stress level in AF pts after CA. Funding Acknowledgement Type of funding source: None

scholarly journals Huge Hiatal Hernia Mimicking a Mass with Compressive Effects on the Left Atrium Causing Paroxysmal Atrial Fibrillation

2019 ◽  
Author(s):  
Murat Akçay ◽  
İlkay Çamlıdağ
Keyword(s):  
Atrial Fibrillation ◽  
Left Atrium ◽  
Hiatal Hernia ◽  
Paroxysmal Atrial Fibrillation ◽  
Valsalva Maneuver ◽  
Cardiac Computed Tomography ◽  
High Rate ◽  
Hernia Surgery ◽  
Mass Size

An 82-year-old female patient presented with complaints of dyspnea and increasing palpitations caused by food reflux. There was no risk factor except hypertension. On physical examination, the heart rate was 120 beats/min and arrhythmic and blood pressure was 130/80 mmHg. Electrocardiography showed high-rate atrial fibrillation. Laboratory parameters were unremarkable. Echocardiography illustrated a hyperechogenic and well-circumscribed mass, 40×55 mm size, in the posterior left atrium (Figure 1, Video 1). The mass size increased with breathing and the Valsalva maneuver. There was no pathology on chest radiography. The atrial fibrillation returned to sinus rhythm spontaneously, but paroxysmal atrial fibrillation attacks were observed, which were related to food reflux at follow-up. Subsequently, cardiac computed tomography, performed to determine the etiology, failed to demonstrate any pathological findings involving the left atrium. However, there was a sliding hernia in the paraesophageal region compressing the left atrium from the inferior-posterior region (Figure 2). Hiatal hernia surgery was recommended on account of the intermittently repeating symptoms. The patient refused the operation, and she is under follow-up with medical treatment.

The impact of climatological parameters on the incidence of paroxysmal atrial fibrillation

2006 ◽  
Vol 13 (Supplement 1) ◽  
pp. S26
Author(s):  
A Douras ◽  
K Tsatiris ◽  
K Pikros ◽  
T Kirlidis ◽  
D Kapsalas ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Paroxysmal Atrial Fibrillation ◽  
The Impact
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