Congenital anomalies and assisted reproductive technologies

2011 ◽  
pp. 283-290
Author(s):  
Mona Aboulghar
Keyword(s):  
Congenital Anomalies ◽  
Assisted Reproductive Technologies ◽  
Reproductive Technologies

scholarly journals Assisted Reproductive Technology and Anorectal Malformation: A Single-Center Experience

2021 ◽  
Vol 9 ◽  
Author(s):  
Chiara Iacusso ◽  
Barbara Daniela Iacobelli ◽  
Francesco Morini ◽  
Giorgia Totonelli ◽  
Milena Viggiano ◽  
...  
Keyword(s):  
Congenital Anomalies ◽  
Anorectal Malformation ◽  
Assisted Reproductive Technologies ◽  
Reproductive Technologies ◽  
Single Center ◽  
Retrospective Case ◽  
Single Center Experience ◽  
Potential Association ◽  
The Relationship ◽  
Control Study

Background: Assisted reproductive technologies (ART) are becoming widespread, accounting for approximately 2% of all births in the western countries. Concerns exist on the potential association of ART with congenital anomalies. Few studies have addressed if a relationship exists between ART and the development of anorectal malformation (ARM). Our aim was to analyze the relationship between ARM and ART.Methods: Single-center retrospective case control study of all patients treated for ARM between 2010 and 2017. Patients with bronchiolitis treated since 2014 were used as controls. Variables analyzed include the following: prevalence of ART, gestational age, birth weight, and maternal age. Patients with ARM born after ART were also compared with those naturally conceived for disease complexity. Fisher's exact and Mann-Whitney U-tests were used as appropriate.Results: Three hundred sixty-nine patients were analyzed (143 cases and 226 controls). Prevalence of ART was significantly higher in ARM patients than in controls [7.6 vs. 3.0%; odds ratio: 2.59 (95% CI, 0.98–0.68); p = 0.05]. Among ARM patients, incidence of VACTERL association (17%) is more frequent in ART babies.Conclusion: Patients with ARM were more likely to be conceived following ART as compared with controls without congenital anomalies. Disease complexity of patients with ARM born after ART seems greater that those born after nonassisted conception.

Intrauterine development of fetus in the conditions of oil technogenesis

2021 ◽  
pp. 56-64
Author(s):  
M. K. Ivanova ◽  
A. N. Bakshaeva ◽  
E. P. Kuznetsova ◽  
E. V. Osipova ◽  
E. V. Mikhajlova ◽  
...  
Keyword(s):  
Congenital Anomalies ◽  
Assisted Reproductive Technologies ◽  
Negative Impact ◽  
Soil Surface ◽  
Reproductive Technologies ◽  
Medical Documentation ◽  
Observation Group ◽  
Intrauterine Development ◽  
Underground Waters ◽  
Musculoskeletal Systems

The oil industry is a leader in the negative impact on all areas of the natural environment. Polluting the atmospheric air, soil, surface and underground waters, oil production processes expose the population living in the adjacent territory to the dangerous effects of xenobiotics. The reproductive system is the most sensitive to environmental problems.The aim of the study was to identify the features of the intrauterine development of fetuses of women living in the territory of oil technogenesis in comparison with the fetuses of women living in a territory without it. A comparative assessment of the frequency of blastogenesis defects in the studied groups was carried out as a result of the analysis of embryological protocols of women who received infertility treatment using methods of assisted reproductive technologies. In order to assess the frequency and structure of defects in embryogenesis and fetogenesis, an analysis of cases of congenital malformations was carried out according to the data of the primary medical documentation of the Medical Genetic Consultation.The identification of differences in the development of embryos was determined by the Pearson agreement criterion. Assessment of statistically significant differences in indicators in the study of the frequency and structure of congenital anomalies in fetuses identified by ultrasound and in newborns, the structure of factors that influenced the mother during pregnancy, which could lead to the development of congenital anomalies and complications of the course of pregnancy, was carried out using t-Student's criterion. Defects of cleavage and blastulation of embryos of women in the observation group were revealed. It was found that the frequency of birth of children with congenital anomalies in the territories of oil technogenesis is statistically significantly higher than in the territories without it. In the observation group, congenital anomalies of the respiratory system detected by ultrasound examination of the fetus, congenital anomalies of the genitals, urinary organs, musculoskeletal systems, multiple malformations revealed antenatally are statistically significantly more common.

Re-imagining Reproduction: Unsettling Metaphors in the History of Imperial Science and Commercial Surrogacy in India

Somatechnics ◽  
2015 ◽  
Vol 5 (1) ◽  
pp. 88-103 ◽  
Author(s):  
Kalindi Vora
Keyword(s):  
Assisted Reproductive Technologies ◽  
Reproductive Technologies ◽  
The Body ◽  
Body Parts ◽  
Colonial History ◽  
Women's Bodies ◽  
Commercial Surrogacy ◽  
Art Practices ◽  
History Of ◽  
Travel Industry

This paper provides an analysis of how cultural notions of the body and kinship conveyed through Western medical technologies and practices in Assisted Reproductive Technologies (ART) bring together India's colonial history and its economic development through outsourcing, globalisation and instrumentalised notions of the reproductive body in transnational commercial surrogacy. Essential to this industry is the concept of the disembodied uterus that has arisen in scientific and medical practice, which allows for the logic of the ‘gestational carrier’ as a functional role in ART practices, and therefore in transnational medical fertility travel to India. Highlighting the instrumentalisation of the uterus as an alienable component of a body and subject – and therefore of women's bodies in surrogacy – helps elucidate some of the material and political stakes that accompany the growth of the fertility travel industry in India, where histories of privilege and difference converge. I conclude that the metaphors we use to structure our understanding of bodies and body parts impact how we imagine appropriate roles for people and their bodies in ways that are still deeply entangled with imperial histories of science, and these histories shape the contemporary disparities found in access to medical and legal protections among participants in transnational surrogacy arrangements.

The role of the growth hormone in assisted reproductive technologies cycles

GYNECOLOGY ◽  
2019 ◽  
Vol 21 (4) ◽  
pp. 6-8
Author(s):  
Andrey Y Romanov ◽  
Anastasiya G Syrkasheva ◽  
Nataliya V Dolgushina ◽  
Elena A Kalinina
Keyword(s):  
Growth Hormone ◽  
Live Birth ◽  
Ovarian Stimulation ◽  
Assisted Reproductive Technologies ◽  
Polycystic Ovary ◽  
Live Birth Rate ◽  
Reproductive Technologies ◽  
Blood Levels ◽  
Main Research ◽  
Poor Ovarian Responders

The paper analyzes the literature data on the use of the growth hormone (GH) in ovarian stimulation in assisted reproductive technologies (ART). Routine use of GH in ovarian stimulation in patients with a normal GH level does not increase pregnancy and childbirth rates in ART. Also, no benefits of using GH have been identified for patients with polycystic ovary syndrome, despite the increase in insulin and IGF-1 blood levels. The main research focus is to study the use of GH in patients with poor ovarian response. According to the meta-analysis conducted by X.-L. Li et al. (2017), GH in ovarian stimulation of poor ovarian responders increases the number of received oocytes, mature oocytes number, reduces the embryo transfer cancellation rate and does not affect the fertilization rate. The pregnancy and live birth rates are significantly higher in the group of GH use - by 1.65 (95% CI 1.23-2.22) and 1.73 (95% CI 1.25-2.40) times, respectively. Thus, it is advisable to use GH in ovarian stimulation in poor ovarian responders, since it allows to increases live birth rate in ART. However, further studies should determine the optimal GH dose and assesse it`s safety in ART programs.

The efficacy of assisted reproductive technologies in patients with uterine fibroids (review)

GYNECOLOGY ◽  
2015 ◽  
pp. 60-64
Author(s):  
N.M. Podzolkova ◽  
◽  
Yu.A. Koloda ◽  
V.V. Korennaya ◽  
K.N. Kayibkhanova ◽  
...  
Keyword(s):  
Assisted Reproductive Technologies ◽  
Uterine Fibroids ◽  
Reproductive Technologies
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