scholarly journals Integrating dissemination and implementation sciences within Clinical and Translational Science Award programs to advance translational research: Recommendations to national and local leaders – ERRATUM

2021 ◽  
Vol 5 (1) ◽  
Author(s):  
Tara G. Mehta ◽  
Jane Mahoney ◽  
Aaron L. Leppin ◽  
Kathleen R. Stevens ◽  
Reza Yousefi-Nooraie ◽  
...  
2019 ◽  
Vol 3 (6) ◽  
pp. 291-294
Author(s):  
Carol Feghali-Bostwick ◽  
Jillian Harvey ◽  
Carissa Hasseler ◽  
Diana Lee-Chavarria ◽  
Perry Halushka

AbstractThe mission of the National Center for Advancing Translational Science (NCATS) is to catalyze the generation of innovative methods and technologies that will enhance the development, testing, and implementation of diagnostics and therapeutics across a wide range of human diseases and conditions.1 NCATS funded a predoctoral TL1 training grant at our institution. We developed a novel team-based Translational Journal Club utilizing three-member teams to find a basic science paper and two clinical study papers that covered a single therapeutic, either a pivotal study or a dissemination and implementation study; one member of the team presented a paper on the above topics in successive weeks. In addition, the trainees attended lectures on: how to design a pivotal clinical trial, dissemination and implementation, and drug development from a basic science discovery through its approval. From these presentations, the trainees appreciated the T0 to T3/4 continuum and its challenges. They also attended sessions on how to present scientific concepts, making them better communicators. The trainees found the Translational Journal club to be very rewarding, illuminating, and providing a much better understanding of the translational research processes required to develop new therapies.


2019 ◽  
Vol 4 (3) ◽  
pp. 152-158 ◽  
Author(s):  
Aaron L. Leppin ◽  
Jane E. Mahoney ◽  
Kathleen R. Stevens ◽  
Stephen J. Bartels ◽  
Laura-Mae Baldwin ◽  
...  

AbstractThe efficient and effective movement of research into practice is acknowledged as crucial to improving population health and assuring return on investment in healthcare research. The National Center for Advancing Translational Science which sponsors Clinical and Translational Science Awards (CTSA) recognizes that dissemination and implementation (D&I) sciences have matured over the last 15 years and are central to its goals to shift academic health institutions to better align with this reality. In 2016, the CTSA Collaboration and Engagement Domain Task Force chartered a D&I Science Workgroup to explore the role of D&I sciences across the translational research spectrum. This special communication discusses the conceptual distinctions and purposes of dissemination, implementation, and translational sciences. We propose an integrated framework and provide real-world examples for articulating the role of D&I sciences within and across all of the translational research spectrum. The framework’s major proposition is that it situates D&I sciences as targeted “sub-sciences” of translational science to be used by CTSAs, and others, to identify and investigate coherent strategies for more routinely and proactively accelerating research translation. The framework highlights the importance of D&I thought leaders in extending D&I principles to all research stages.


2020 ◽  
Vol 4 (3) ◽  
pp. 168-175 ◽  
Author(s):  
Reza Yousefi Nooraie ◽  
Bethany M. Kwan ◽  
Elizabeth Cohn ◽  
Mona AuYoung ◽  
Megan Clarke Roberts ◽  
...  

AbstractDissemination and implementation (D&I) science is dedicated to studying how to effectively translate and apply research in real-world contexts. There has been increasing interest in health equity within the D&I field to ensure the equitable implementation of evidence-based programs/practices across a range of diverse populations and settings. At the same time, health equity researchers recognize the potential of D&I science to promote the more widespread dissemination, implementation, and sustainment of evidence-based interventions to address health inequities. The National Center for Accelerating Clinical and Translational Science Clinical and Translational Science Award (CTSA) Program has been a champion for community engagement and translational scholarship in its mission to improve individual and population health. The overall CTSA infrastructure and resources within and among CTSA hubs are well-equipped to facilitate a health equity focus to D&I across the phases of translational research. This paper proposes a framework that demonstrates the interaction and opportunities between health equity and D&I science and highlights how CTSAs can support and facilitate wider efforts in translational research with a focus on equitable D&I.


2020 ◽  
Vol 4 (4) ◽  
pp. 371-371
Author(s):  
Aaron L. Leppin ◽  
Jane E. Mahoney ◽  
Kathleen R. Stevens ◽  
Stephen J. Bartels ◽  
Laura-Mae Baldwin ◽  
...  

2010 ◽  
Vol 24 (1) ◽  
pp. 9-24 ◽  
Author(s):  
Nancy Fugate Woods ◽  
Diane L. Magyary

The heightened demand for benefit from scientific contributions has driven scientific initiatives such as the NIH Roadmap, the recently established Clinical Translational Science Awards, and requests for applications for funding by the National Institutes of Health (NIH) and Agency for Health Research and Quality (AHRQ) to support studies of translational efforts. Our article focuses on a rapidly developing area—translational research—and the value, if not necessity, of nursing’s contributions to interdisciplinary efforts. Our objectives are to: 1. Relate the changing nature of research (and clinical practice) to the need for interdisciplinary efforts in translational research; 2. Delineate the skills necessary for translation of research to clinical and community-based practice; 3. Review nursing’s contributions to national interdisciplinary initiatives; 4. Identify critical areas for nursing leadership in translational research and consequences of our absence from these efforts; and 5. Propose a translational research agenda for nursing.


2019 ◽  
Vol 22 (1) ◽  
pp. 63-71
Author(s):  
Tiffany L. Young ◽  
Lori Carter-Edwards ◽  
Leah Frerichs ◽  
Melissa A. Green ◽  
Kristen Hassmiller-Lich ◽  
...  

Cultivating strong partnerships among community and academic stakeholders expedites the translation of research findings into practice and communities by enhancing opportunities for research dissemination and implementation. However, the lack of systematic methods for community stakeholder engagement may decelerate the translational research process. The North Carolina Translational Research and Clinical Sciences Institute implemented an innovative approach to community engagement called the Action Learning Cohort (ALC) Series. The ALC Series, a workgroup extension of a professional conference, used action learning and systems thinking strategies to conceptualize and develop a product aimed at preventing, treating, and controlling hypertension in eastern North Carolina. We evaluated the acceptability and practicality of the ALC Series using survey, focus group, and interview pilot data. Action learning and systems thinking strategies led ALC stakeholders to develop and disseminate The Empathy Building Resource Guide: A Toolkit for Enhancing Patient–Provider Relationships in the Treatment, Management, and Prevention of Hypertension. Stakeholders rated the Series as satisfactory and acknowledged gains in knowledge and desire for engagement with fellow ALC stakeholders beyond the Series. The ALC Series approach is a potentially practical and acceptable model for systematically engaging community stakeholders in translating knowledge into a product that addresses health topics like hypertension.


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