Variable Duration of Viral Shedding in Cancer Patients with COVID-19

Abstract In this retrospective study of 105 SARS COV-2 infected cancer patients with longitudinal nasopharyngeal sampling, the duration of viral shedding and time to attain cycle threshold >30 was longer in patients with hematologic malignancy than those with solid tumors. These findings have important public health implications.

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Characteristics and outcomes of cancer patients ≥80 years treated with chemotherapy at a comprehensive cancer center

Journal of Clinical Oncology ◽

10.1200/jco.2006.24.18_suppl.8548 ◽

2006 ◽

Vol 24 (18_suppl) ◽

pp. 8548-8548

Author(s):

P. Jiang ◽

M. Choi ◽

D. Smith ◽

L. Heilbrun ◽

S. M. Gadgeel

Keyword(s):

Cancer Patients ◽

Solid Tumors ◽

Solid Tumor ◽

Hematologic Malignancy ◽

Survival Rates ◽

The United States ◽

Comprehensive Cancer Center ◽

Cancer Center ◽

Tumor Patients ◽

Hematologic Cancer

8548 Background: The percentage of cancer patients ≥ 80 years old is expected to rise in the United States. However data are limited on use of chemotherapy in this group of patients. Methods: Retrospective identification of patients who received systemic chemotherapy at our cancer center between 1/1/2000 to 12/31/2004 was performed using the computer generated pharmacy data and medical records. Patients who had diagnosis of cancer and ≥ 80 years were included in the study; patients receiving only supportive care, hormonal therapy, or oral chemotherapy were excluded. The protocol for this study was approved by the Wayne State University IRB. Results: A total of 133 patients ≥ 80 years who received chemotherapy was analyzed. The median age was 83 and 31% of the patients were ≥ 85 years. There were more females (61%) than males (39%). The gender distribution was more even (47% v. 53%) after excluding gender specific tumors. The racial distribution was diverse- Whites 65 (49%); Blacks 41 (31%); Other 18 (13%); Unknown 9 (7%). 16% of the patients had hematologic malignancy and 84% had solid tumors. Gynecological cancers (32%) followed by aerodigestive cancers (26%) were the most common solid tumors. Solid tumor patients primarily had regional (48%) or distant (45%) disease. During the first regimen, 512 cycles of chemotherapy was delivered with a median of 3 cycles per patient (range 1–24 cycles); 40% of patients received only 2 cycles of chemotherapy. 64% of patients were able to receive chemotherapy without 2nd cycle delay. The distribution of single or multidrug regimens was fairly similar; Solid tumors 52% v. 48%; Hematologic cancers 43% v. 57%. Carboplatin and paclitaxel (22%) was the most common regimen among solid tumor patients. 26% of all patients received a second regimen. The 1 year survival rates among hematologic cancer and solid tumor patients were 65% and 48%, respectively. Stage of disease was the only statistically significant factor predicting survival. Conclusions: In this diverse group of cancer patients ≥ 80 years old and selected for chemotherapy, the treatment was feasible. The survival outcomes in this elderly population were comparable to those of a younger patient population suggesting that the treatment is beneficial. No significant financial relationships to disclose.

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High-dose fluconazole therapy for cancer patients with solid tumors and candidemia: an observational, noncomparative retrospective study

Supportive Care in Cancer ◽

10.1007/s00520-004-0601-x ◽

2004 ◽

Vol 12 (7) ◽

Cited By ~ 14

Author(s):

H.A. Torres ◽

D.P. Kontoyiannis ◽

K.V.I. Rolston

Keyword(s):

Retrospective Study ◽

Cancer Patients ◽

Solid Tumors ◽

High Dose ◽

Fluconazole Therapy

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Study of Prescription Pattern of Analgesics in Terminally Ill Cancer Patients with Solid Tumors in a Tertiary Care Centre: A Retrospective Study

Indian Journal of Anaesthesia and Analgesia ◽

10.21088/ijaa.2349.8471.5218.22 ◽

2018 ◽

Vol 5 (2) ◽

pp. 283-288

Author(s):

Thomas George ◽

◽

Princy L. Palatty ◽

Soniya Abraham ◽

Karadka Ramdas Thilakchand ◽

...

Keyword(s):

Retrospective Study ◽

Cancer Patients ◽

Solid Tumors ◽

Tertiary Care ◽

Terminally Ill ◽

Care Centre ◽

Tertiary Care Centre ◽

Prescription Pattern ◽

Terminally Ill Cancer Patients

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Skin Carotenoids in Public Health and Nutricosmetics: The Emerging Roles and Applications of the UV Radiation-Absorbing Colourless Carotenoids Phytoene and Phytofluene

Nutrients ◽

10.3390/nu11051093 ◽

2019 ◽

Vol 11 (5) ◽

pp. 1093 ◽

Cited By ~ 17

Author(s):

Antonio J. Meléndez-Martínez ◽

Carla M. Stinco ◽

Paula Mapelli-Brahm

Keyword(s):

Public Health ◽

Uv Radiation ◽

Light Absorption ◽

Science And Technology ◽

Food Science ◽

Important Public Health ◽

Health Implications ◽

Health Promoting

In this work, the importance of dietary carotenoids in skin health and appearance is comprehensively reviewed and discussed. References are made to their applications in health-promoting and nutricosmetic products and the important public health implications that can be derived. Attention is focused on the colourless UV radiation (UVR)-absorbing dietary carotenoids phytoene and phytofluene, which are attracting increased interest in food science and technology, nutrition, health and cosmetics. These compounds are major dietary carotenoids, readily bioavailable, and have been shown to be involved in several health-promoting actions, as pinpointed in recent reviews. The growing evidence that these unique UVR-absorbing carotenoids with distinctive structures, properties (light absorption, susceptibility to oxidation, rigidity, tendency to aggregation, or even fluorescence, in the case of phytofluene) and activities can be beneficial in these contexts is highlighted. Additionally, the recommendation that the levels of these carotenoids are considered in properly assessing skin carotenoid status is made.

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Stillbirth rate in Bhutan: a retrospective facility-based study

Bhutan Health Journal ◽

10.47811/bhj.66 ◽

2018 ◽

Vol 4 (2) ◽

pp. 35-38

Author(s):

Pema Lethro ◽

Kinga Jamphel ◽

Vandana Joshi ◽

Chandralal Mongar ◽

Lobzang Tshering ◽

...

Keyword(s):

Public Health ◽

Information System ◽

Retrospective Study ◽

Health Concern ◽

Stillbirth Rate ◽

Public Health Concern ◽

Data Set ◽

Important Public Health ◽

Live Births ◽

One Year

Introduction: Stillbirth is an important public health concern; yet there is no reliable stillbirth rate for Bhutan. Hence the aim of this study was to estimate the stillbirth rate for Bhutan. Methods: A retrospective study was carried out for live and stillbirths recorded in delivery registers of all 253 health facilities across the country for a period of one year commencing 1st January till 31st December 2015. Results: There were a total of 11,126 live births and 108 stillbirths documented in delivery registers. The stillbirth rate from this data set was 10 per 1000 live births. Conclusions: The stillbirth rate for Bhutan from this study is 10 per 1000 live births lower than 16 per 1000 live births estimated in Lancet Series 2015. In order to find the true burden of stillbirths in the country, a surveillance may be instituted which can facilitate the prevention efforts while at the same time enable to strengthen information system.

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