Fruit and vegetable intake and breast cancer prognosis: a meta-analysis of prospective cohort studies

AbstractThe effect of fruit and vegetable intake on breast cancer prognosis is controversial. Thus, a meta-analysis was carried out to explore their associations. A comprehensive search was conducted in PubMed, Web of Science, OVID, ProQuest and Chinese databases from inception to April 2016. The summary hazard ratios (HR) and 95 % CI were estimated using a random effects model if substantial heterogeneity existed and using a fixed effects model if not. Subgroup analyses and sensitivity analyses were also performed. In total, twelve studies comprising 41 185 participants were included in the meta-analysis. Comparing the highest with the lowest, the summary HR for all-cause mortality were 1·01 (95 % CI 0·72, 1·42) for fruits and vegetables combined, 0·96 (95 % CI 0·83, 1·12) for total vegetable intake, 0·99 (95 % CI 0·89, 1·11) for cruciferous vegetable intake and 0·88 (95 % CI 0·74, 1·05) for fruit intake; those for breast cancer-specific mortality were 1·05 (95 % CI 0·77, 1·43) for total vegetable intake and 0·94 (95 % CI 0·69, 1·26) for fruit intake; and those for breast cancer recurrence were 0·89 (95 % CI 0·53, 1·50) for total vegetable intake and 0·98 (95 % CI 0·76, 1·26) for cruciferous vegetable intake. This meta-analysis found no significant associations between fruit and vegetable intake and breast cancer prognosis.

Download Full-text

Fruit and vegetable intake and bones: A systematic review and meta-analysis

PLoS ONE ◽

10.1371/journal.pone.0217223 ◽

2019 ◽

Vol 14 (5) ◽

pp. e0217223 ◽

Cited By ~ 1

Author(s):

Juliana E. Brondani ◽

Fabio V. Comim ◽

Liziane M. Flores ◽

Lígia Araújo Martini ◽

Melissa O. Premaor

Keyword(s):

Systematic Review ◽

Vegetable Intake ◽

Meta Analysis ◽

Fruit And Vegetable Intake ◽

Fruit And Vegetable

Download Full-text

Fruit and Vegetable Intake and the Risk of Chronic Obstructive Pulmonary Disease: A Dose-Response Meta-Analysis of Observational Studies

BioMed Research International ◽

10.1155/2020/3783481 ◽

2020 ◽

Vol 2020 ◽

pp. 1-12

Author(s):

Hongrui Zhai ◽

Yu Wang ◽

Wenjie Jiang

Keyword(s):

Chronic Obstructive Pulmonary Disease ◽

Dose Response ◽

Vegetable Intake ◽

Meta Analysis ◽

Fruit And Vegetable Intake ◽

Chronic Obstructive ◽

Response Relationship ◽

Fruit And Vegetable ◽

Dose Response Relationship ◽

Obstructive Pulmonary Disease

Object. Results on the associations of fruit and vegetable intake with risk of chronic obstructive pulmonary disease (COPD) are still in conflict. Hence, we conducted a meta-analysis to quantitatively evaluate the association between fruit and vegetable intake and the risk of COPD. Methods. PubMed, Web of Science, and China National Knowledge Infrastructure (CNKI) were searched for relevant studies published up to September 2019. Combined relative risks (RRs) and 95% confidence intervals (CIs) were calculated with the random effects model (REM). Dose-response relationship was assessed by the restricted cubic spline model. Results. There are 8 studies involving 5,787 COPD cases among 244,154 participants included in this meta-analysis. For the highest versus the lowest level, the pooled RR of COPD was 0.75 (95% CI, 0.68–0.84; I2 = 46.7%) for fruits plus vegetables, 0.72 (95% CI, 0.66–0.79; I2 = 1.3%) for fruits, and 0.76 (95% CI, 0.63–0.92; I2 = 62.7%) for vegetables. In subgroup analysis of fruit plus vegetable intake and COPD risk, the inverse association exists in all three study designs. A nonlinear dose-response relationship was found for COPD risk with fruit (Pnon−linearity<0.01). Conclusions. This meta-analysis indicates that fruit and vegetable intake might be related to a lower risk of COPD.

Download Full-text

Fruit and vegetable intake and incidence of type 2 diabetes mellitus: systematic review and meta-analysis

BMJ ◽

10.1136/bmj.c4229 ◽

2010 ◽

Vol 341 (aug18 4) ◽

pp. c4229-c4229 ◽

Cited By ~ 427

Author(s):

P. Carter ◽

L. J. Gray ◽

J. Troughton ◽

K. Khunti ◽

M. J. Davies

Keyword(s):

Diabetes Mellitus ◽

Systematic Review ◽

Type 2 Diabetes ◽

Type 2 Diabetes Mellitus ◽

Vegetable Intake ◽

Meta Analysis ◽

Fruit And Vegetable Intake ◽

Fruit And Vegetable

Download Full-text

Fruit and vegetable intake and risk of wheezing and asthma: a systematic review and meta-analysis

Nutrition Reviews ◽

10.1111/nure.12121 ◽

2014 ◽

Vol 72 (7) ◽

pp. 411-428 ◽

Cited By ~ 44

Author(s):

Ensiyeh Seyedrezazadeh ◽

Masoud Pour Moghaddam ◽

Khalil Ansarin ◽

Mohammad Reza Vafa ◽

Sangita Sharma ◽

...

Keyword(s):

Systematic Review ◽

Vegetable Intake ◽

Meta Analysis ◽

Fruit And Vegetable Intake ◽

Fruit And Vegetable

Download Full-text

Abstract 5325A: Fruit and vegetable intake and risk of breast cancer: Pooled analysis of the Nurses’ Health Study and the Nurses’ Health Study II

10.1158/1538-7445.am2017-5325a ◽

2017 ◽

Author(s):

Maryam S. Farvid ◽

Walter C. Willett ◽

A. Heather Eliassen

Keyword(s):

Breast Cancer ◽

Vegetable Intake ◽

Pooled Analysis ◽

Fruit And Vegetable Intake ◽

Health Study ◽

Fruit And Vegetable

Download Full-text

Relationships Between Food Security, Fruit and Vegetable Availability, and Fruit and Vegetable Intake in Elementary Children and Their Parents

Current Developments in Nutrition ◽

10.1093/cdn/nzaa043_136 ◽

2020 ◽

Vol 4 (Supplement_2) ◽

pp. 285-285

Author(s):

Michaela Sossamon ◽

Derek Miketinas

Keyword(s):

Food Security ◽

Vegetable Intake ◽

Fruit And Vegetable Intake ◽

Elementary Children ◽

Fruit Intake ◽

Fruit And Vegetable ◽

School Garden ◽

Cross Sectional ◽

Fruit Availability ◽

At Home

Abstract Objectives The purpose of this cross-sectional analysis is to explore baseline findings on the relationships between food security, fruit and vegetable availability, and fruit and vegetable intake in elementary children and their parents before the start of a school-garden program. Methods Third-grade students (n = 154) and their parents were recruited from a Texas elementary school that participates in a school-garden program. Prior to the start of the program, student participants along with one of their parents completed the National Cancer Institute's All-Day Screener to assess fruit, juice, and vegetable intake. Parent participants also completed other validated questionnaires to assess home availability of fruits and vegetables and food security. Regression and ANOVA were used to examine the relationships between food security, fruit and vegetable availability at home, and fruit and vegetable intake in parent and student participants. Results A total of 64 students provided consent, and 39 students (∼58% female), each with one parent (∼97% female), completed the questionnaires. Parents who reported low food security had significantly greater total fruit and vegetable intake (4.7 servings/day) along with their children (6.0 servings/day) compared with parents (2.8 servings/day) and children (3.3 servings/day) with high food security. Fruit availability at home was positively correlated with fruit intake in parents (β = 0.18; P = .0261; R2 = 0.13; ) but not children (P = .8931). No significant associations were found between vegetable availability and vegetable intake in student or parent participants. Conclusions These baseline findings indicate greater fruit and vegetable intake for children and parents with low food security, which may be due to differences in fruit intake rather than vegetable intake. Although greater fruit intake was associated with fruit availability in the home for parents, this association was not observed for children. Funding Sources None.

Download Full-text

A free-produce stand on campus: impact on fruit and vegetable intake in Dutch university students

Public Health Nutrition ◽

10.1017/s1368980019003574 ◽

2020 ◽

Vol 23 (5) ◽

pp. 924-934

Author(s):

Nicole van den Bogerd ◽

Herman Peppelenbos ◽

Roos Leufkens ◽

Jacob C Seidell ◽

Jolanda Maas ◽

...

Keyword(s):

Vegetable Intake ◽

Fruit And Vegetable Intake ◽

Test Design ◽

Fruit Intake ◽

Regression Analyses ◽

Fruit And Vegetable ◽

Potted Plants ◽

Subgroup Analyses ◽

Post Test ◽

Pass Through

AbstractObjective:To investigate the effects of providing free fruit and snack vegetables at a university on students’ fruit intake, snack vegetable intake and total vegetable intake.Design:Free fruit and raw snack vegetables (e.g. bite-sized tomatoes) were provided in a stand in the form of a miniature wooden house located in the central hall of the university’s main building, which students regularly pass through on their way to lectures and the cafeteria. Three interventions tested with a pre-test/post-test design were performed. In these three interventions, small changes to the appearance of the stand were made, such as placing potted plants around it. Demographic characteristics and fruit and vegetable intakes were assessed with questionnaires.Setting:A Dutch university of applied science.Participants:Intervention 1 included 124 students; Intervention 2 included ninety-two students; Intervention 3 included 237 students.Results:Longitudinal linear regression analyses showed that post-test snack vegetable intake was consistently higher compared with pre-test. In the three interventions, post-test snack vegetable intakes were between 11 and 14 g/d higher than at the pre-test, which is comparable to three bite-sized tomatoes. No differences in fruit intake or total vegetable intake were found. Subgroup analyses showed that, in all three interventions, students with the lowest pre-test fruit intake and total vegetable intake reported the largest increase in fruit intake and snack vegetable intake after the interventions.Conclusions:Providing free fruit and vegetables to students at their university might be beneficial for those with low habitual intakes.

Download Full-text

Expression of CXCR4 and breast cancer prognosis: a systematic review and meta-analysis

BMC Cancer ◽

10.1186/1471-2407-14-49 ◽

2014 ◽

Vol 14 (1) ◽

Cited By ~ 54

Author(s):

Zhigang Zhang ◽

Chao Ni ◽

Wuzhen Chen ◽

Ping Wu ◽

Zhen Wang ◽

...

Keyword(s):

Breast Cancer ◽

Systematic Review ◽

Meta Analysis ◽

Breast Cancer Prognosis ◽

Cancer Prognosis

Download Full-text

Fruit and Vegetable Intake in Adolescents: Association with Socioeconomic Status and Exposure to Supermarkets and Fast Food Outlets

Journal of Nutrition and Metabolism ◽

10.1155/2012/185484 ◽

2012 ◽

Vol 2012 ◽

pp. 1-9 ◽

Cited By ~ 15

Author(s):

Chalida M. Svastisalee ◽

Bjørn E. Holstein ◽

Pernille Due

Keyword(s):

Social Class ◽

Fast Food ◽

Vegetable Intake ◽

Fruit And Vegetable Intake ◽

Fruit Intake ◽

Food Outlet ◽

Fruit And Vegetable ◽

Older Children ◽

Fast Food Outlet ◽

Outlet Concentration

Background. We investigated differences in family social class associations between food outlet exposure and fruit and vegetable intake.Methods. We supplemented data from the 2006 Health Behavior in School Aged Children Study (n=6,096) with geocoded food outlet information surrounding schools (n=80). We used multilevel logistic regression to examine associations between infrequent fruit and vegetable intake and supermarket and fast food outlet concentration, stratified by family social class.Results. Boys and older children were most likely to eat fruit and vegetables infrequently. High fast food outlet exposure was marginally significant for low fruit intake in low social class children only. Children from middle and low social class backgrounds attending schools with combined high fast food outlet/low supermarket exposure were most likely to report infrequent fruit intake (ORlow=1.60;CI: 1.02–2.45;ORmid=1.40;CI: 1.03–190). Children from low social class backgrounds were also likely to report infrequent vegetable intake, given low supermarket and high fast food outlet exposure (OR=1.79;CI: 0.99–3.21).Conclusion. Our findings suggest social class modifies the relationship between intake and food outlet concentration. School interventions improving fruit and vegetable intake should consider neighborhood surroundings, targetting older children from low social class backgrounds.

Download Full-text